Kristine Holgersen
Postdoc
Comparative Pediatrics and Nutrition
Dyrlægevej 68
1870 Frederiksberg C
Education
PhD, 11 February 2015, Novo Nordisk A/S and University of Copenhagen
MSc in Veterinary Medicine (DVM), 22 August 2011, University of Copenhagen
BSc in Veterinary Medicine, 30 June 2008, University of Copenhagen
Positions
Jan 2024 – Jan 2025: Postdoc at Comparative Pediatric and Nutrition, Dept. of Veterinary and Animal Sciences, University of Copenhagen
- Study responsible for in vivo studies in preterm pigs, e.g. investigating the effects of:
- Different milk caseins on gut and immune maturation. Collaboration with Arla Food Ingredients and Aarhus University (the BMCIII and Casgut projects)
- Absorption of extracellular vesicles in the intestine. Collaboration with Arla Food Ingredients and Aarhus University (GutBioMod project)
Jan 2021 – Dec 2023: Scientist at Odense University Hospital, Region of Southern Denmark
- Human infant studies: Analyses of the metabolic profile, amino acids and early growth in very preterm infants fed fortified human breast milk from the FortiColos Trial.
Jan 2019 – Dec 2021: Postdoc at Comparative Pediatric and Nutrition, Dept. of Veterinary and Animal Sciences, University of Copenhagen
- Study responsible for studies investigating the effects of exogenous systemic IGF-1 treatment on growth and organ development in preterm pigs. A collaboration with Takeda Pharmaceuticals.
May 2015 – Nov 2018: Compliance Consultant at Epista Life Science
- Projects at CMC Development and Biopharm, Novo Nordisk A/S - testing and qualification of systems used in the GMP-regulated area for manufacturing drugs for clinical trials.
Nov. 2014 - April 2015: Scientific assistant at University of Southern Denmark
- Establishment of an experimental mouse model of colitis with a humanized gut microbiota
- DNA extraction and analysis of material from inflammatory bowel disease patients.
Sep 2011 – Oct 2014: PhD student at the Novo Nordisk – LIFE In Vivo Pharmacology Centre (LIFEPHARM). Dept. of Immunopharmacology, Novo Nordisk A/S and Dept. of Veterinary Disease Biology, Faculty of Health and Medical Sciences, University of Copenhagen.
- Implementation and characterization of experimental mouse models of colitis and preclinical drug screening. PhD project entitled Piroxicam-accelerated colitis in interleukin-10 knockout mice; an in vivo model mimicking human inflammatory bowel disease.
Sep 2013- Dec 2013: Academic Visitor at the University of Oxford. Nuffield Department of Medicine, Translational Gastroenterology Unit, Powrie Laboratory.
- Preclinical testing of a new Novo Nordisk lead compound in a mouse model of chronic colitis.
Teaching and supervision
- Practical and theoretical courses in laboratory animal science for Bachelor-, Master- and PhD students.
- Lecture on Bachelor course ‘Sygdomslære og farmakologi’ at University of Copenhagen
- Co- supervising 5 veterinary master students during their master thesis project and 2 laboratory technician trainees in practical experimental work and during their final project.
Academic awards and honours:
- Runner-up, Best poster presentation, IVP annual meeting, Marts 2014.
SHARE Young Scientist Research Award for outstanding achievement poster presentation, Nov 2011
Other scientific skills
Poster and oral presentation; I have presented at several scientific congresses and academic meetings, incl.:
- jENS Meeting, Rome 2023
- ESPGHAN, Copenhagen 2022
- Digestive Disease Week, Chicago 2014
- Congress of the European Crohn’s and Colitis Organisation (ECCO), Barcelona 2012/Vienna 2013
- European Medicines Research Training Network (EMTRAIN) PhD Workshop, Stevenage (GSK) 2013
- European Congress of Immunology, Glasgow 2012.
Training courses:
- Statistical methods for science (SmS), SCIENCE, University of Copenhagen
- Data Integrity. Requirement for a GMP-compliant Data Life Cycle. European Compliance Academy
- The 3-year In Vivo Pharmacology Research Training Programme. Faculty of Health and Medical sciences, University of Copenhagen as a collaboration with the pharmaceutical industry
- In Vivo Pharmacology - Biologic variation, reproducibility and predictability in preclinical drug testing in lab. animals. Faculty of Health and Medical sciences, University of Copenhagen
- Practical course in cellular immunology. Faculty of Health and Medical sciences, University of Copenhagen
- Statistics for Veterinarians. Faculty of Health and Medical sciences, University of Copenhagen
- Laboratory Animal Science - Cat. C Course. Faculty of Health and Medical sciences, University of Copenhagen.
- Home Office, ANIMALS (SCIENTIFIC PROCEDURES) ACT 1986, personal licence, UK Government.
Excellent Microsoft Office Skills (Excel, Powerpoint, Word, Adobe Acrobat, Outlook etc.)
Language skills; Danish is native and English is fluent (written and spoken).
ID: 388261863
Most downloads
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619
downloads
Validation of Piroxicam-Accelerated Colitis in the Interleukin-10 Knock out Mouse - a Preclinical Model Mimicking Human Inflammatory Bowel Disease
Research output: Contribution to conference › Poster › Research › peer-review
Published -
115
downloads
Evaluating IL-21 as a Potential Therapeutic Target in Crohn's Disease
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
38
downloads
Supplemental Insulin-Like Growth Factor-1 and Necrotizing Enterocolitis in Preterm Pigs
Research output: Contribution to journal › Journal article › Research › peer-review
Published