Kristine Holgersen

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• CV
• Research outputs
• Prizes
• Activities
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Education

PhD, 11 February 2015, Novo Nordisk A/S and University of Copenhagen

MSc in Veterinary Medicine (DVM), 22 August 2011, University of Copenhagen

BSc in Veterinary Medicine, 30 June 2008, University of Copenhagen

Positions

Jan 2024 – Jan 2025: Postdoc at Comparative Pediatric and Nutrition, Dept. of Veterinary and Animal Sciences, University of Copenhagen

• Study responsible for in vivo studies in preterm pigs, e.g. investigating the effects of:
• Different milk caseins on gut and immune maturation. Collaboration with Arla Food Ingredients and Aarhus University (the BMCIII and Casgut projects)
• Absorption of extracellular vesicles in the intestine. Collaboration with Arla Food Ingredients and Aarhus University (GutBioMod project)

 

Jan 2021 – Dec 2023: Scientist at Odense University Hospital, Region of Southern Denmark

• Human infant studies: Analyses of the metabolic profile, amino acids and early growth in very preterm infants fed fortified human breast milk from the FortiColos Trial.

 

Jan 2019 – Dec 2021: Postdoc at Comparative Pediatric and Nutrition, Dept. of Veterinary and Animal Sciences, University of Copenhagen

• Study responsible for studies investigating the effects of exogenous systemic IGF-1 treatment on growth and organ development in preterm pigs. A collaboration with Takeda Pharmaceuticals.

 

May  2015 – Nov 2018: Compliance Consultant at Epista Life Science

• Projects at CMC Development and Biopharm, Novo Nordisk A/S - testing and qualification of systems used in the GMP-regulated area for manufacturing drugs for clinical trials.

Nov. 2014 - April 2015: Scientific assistant at University of Southern Denmark

• Establishment of an experimental mouse model of colitis with a humanized gut microbiota
• DNA extraction and analysis of material from inflammatory bowel disease patients.

Sep 2011 – Oct 2014: PhD student at the Novo Nordisk – LIFE In Vivo Pharmacology Centre (LIFEPHARM). Dept. of Immunopharmacology, Novo Nordisk A/S and Dept. of Veterinary Disease Biology, Faculty of Health and Medical Sciences, University of Copenhagen.

• Implementation and characterization of experimental mouse models of colitis and preclinical drug screening. PhD project entitled Piroxicam-accelerated colitis in interleukin-10 knockout mice; an in vivo model mimicking human inflammatory bowel disease.

 

Sep 2013- Dec 2013: Academic Visitor at the University of Oxford. Nuffield Department of Medicine, Translational Gastroenterology Unit, Powrie Laboratory.

• Preclinical testing of a new Novo Nordisk lead compound in a mouse model of chronic colitis.

Teaching and supervision

• Practical and theoretical courses in laboratory animal science for Bachelor-, Master- and PhD students.
• Lecture on Bachelor course ‘Sygdomslære og farmakologi’ at University of Copenhagen
• Co- supervising 5 veterinary master students during their master thesis project and 2 laboratory technician trainees in practical experimental work and during their final project.

Academic awards and honours:

• Runner-up, Best poster presentation, IVP annual meeting, Marts 2014.

SHARE Young Scientist Research Award for outstanding achievement poster presentation, Nov 2011

Other scientific  skills

Poster and oral presentation; I have presented at several scientific congresses and academic meetings, incl.:

• jENS Meeting, Rome 2023
• ESPGHAN, Copenhagen 2022
• Digestive Disease Week, Chicago 2014
• Congress of the European Crohn’s and Colitis Organisation (ECCO), Barcelona 2012/Vienna 2013
• European Medicines Research Training Network (EMTRAIN) PhD Workshop, Stevenage (GSK) 2013

• European Congress of Immunology, Glasgow 2012.

 

Training courses:

• Statistical methods for science (SmS), SCIENCE, University of Copenhagen
• Data Integrity. Requirement for a GMP-compliant Data Life Cycle. European Compliance Academy
• The 3-year In Vivo Pharmacology Research Training Programme. Faculty of Health and Medical sciences, University of Copenhagen as a collaboration with the pharmaceutical industry
• In Vivo Pharmacology - Biologic variation, reproducibility and predictability in preclinical drug testing in lab. animals. Faculty of Health and Medical sciences, University of Copenhagen
• Practical course in cellular immunology. Faculty of Health and Medical sciences, University of Copenhagen
• Statistics for Veterinarians. Faculty of Health and Medical sciences, University of Copenhagen
• Laboratory Animal Science - Cat. C Course. Faculty of Health and Medical sciences, University of Copenhagen.
• Home Office, ANIMALS (SCIENTIFIC PROCEDURES) ACT 1986, personal licence, UK Government.

Excellent Microsoft Office Skills (Excel, Powerpoint, Word, Adobe Acrobat, Outlook etc.)

Language skills; Danish is native and English is fluent (written and spoken).