Holger Grohganz

Holger Grohganz

Associate Professor


  1. 2020
  2. Published

    Influence of polymer addition on the amorphization, dissolution and physical stability of co-amorphous systems

    Liu, J., Grohganz, Holger & Rades, Thomas, 2020, In: International Journal of Pharmaceutics. 588, p. 1-9 9 p., 119768.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Preparation of Co-Amorphous Systems by Freeze-Drying

    Wostry, M., Plappert, H. & Grohganz, Holger, 2020, In: Pharmaceutics. 12, 10, 12 p., 941.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. 2019
  5. Published

    In situ co-amorphisation in coated tablets – The combination of carvedilol with aspartic acid during immersion in an acidic medium

    Petry, I., Löbmann, Korbinian, Grohganz, Holger, Rades, Thomas & Leopold, C. S., 10 Mar 2019, In: International Journal of Pharmaceutics. 558, p. 357-366 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Transformations between Co-Amorphous and Co-Crystal Systems and Their Influence on the Formation and Physical Stability of Co-Amorphous Systems

    Wu, W., Wang, Y., Löbmann, Korbinian, Grohganz, Holger & Rades, Thomas, 4 Mar 2019, In: Molecular Pharmaceutics. 16, 3, p. 1294-1304 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Whey proteins as stabilizers in amorphous solid dispersions

    Mishra, J., Bohr, A., Rades, Thomas, Grohganz, Holger & Löbmann, Korbinian, 1 Feb 2019, In: European Journal of Pharmaceutical Sciences. 128, p. 144-151 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Process Optimization and Upscaling of Spray-Dried Drug-Amino acid Co-Amorphous Formulations

    Kasten, G., Duarte, Í., Paisana, M., Löbmann, Korbinian, Rades, Thomas & Grohganz, Holger, 9 Jan 2019, In: Pharmaceutics. 11, 1, 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Characterising glass transition temperatures and glass dynamics in mesoporous silica-based amorphous drugs

    Kissi, E. O., Ruggiero, M. T., Hempel, N. J., Song, Z., Grohganz, Holger, Rades, Thomas & Löbmann, Korbinian, 1 Jan 2019, In: Physical Chemistry Chemical Physics. 21, 35, p. 19686-19694 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Dipeptides as co-formers in co-amorphous systems

    Wu, W., Löbmann, Korbinian, Schnitzkewitz, J., Knuhtsen, A., Pedersen, D. S., Rades, Thomas & Grohganz, Holger, 1 Jan 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 134, p. 68-76 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Influence of Glass Forming Ability on the Physical Stability of Supersaturated Amorphous Solid Dispersions

    Blaabjerg, L. I., Bulduk, B., Lindenberg, E., Löbmann, Korbinian, Rades, Thomas & Grohganz, Holger, 1 Jan 2019, In: Journal of Pharmaceutical Sciences. 108, 8, p. 2561-2569

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    A co-amorphous form of a substance and a protein

    Mishra, J., Bohr, A., Berg, T. H. A., Löbmann, Korbinian, Rades, Thomas, Grohganz, Holger & Water, J. J., 2019, Patent No. US201903078886A1

    Research output: Patent

  13. Published

    Co-former selection for co-amorphous drug-amino acid formulations

    Kasten, G., Löbmann, Korbinian, Grohganz, Holger & Rades, Thomas, 2019, In: International Journal of Pharmaceutics. 557, p. 366-373

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Efflux Inhibitor Bicalutamide Increases Oral Bioavailability of the Poorly Soluble Efflux Substrate Docetaxel in Co-Amorphous Anti-Cancer Combination Therapy

    Bohr, A., Nascimento, T. L., Harmankaya, N., Weisser, J. J., Wang, Y., Grohganz, Holger, Rades, Thomas & Löbmann, Korbinian, 2019, In: Molecules. 24, 2, 13 p., 266.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Exploring the chemical space for freeze-drying excipients

    Meng-Lund, H., Holm, T. P., Poso, A., Jørgensen, Lene, Rantanen, Jukka & Grohganz, Holger, 2019, In: International Journal of Pharmaceutics. 566, p. 254-263 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Using dextran of different molecular weights to achieve faster freeze-drying and improved storage stability of lactate dehydrogenase

    Larsen, B. S., Skytte, J., Svagan, A. J., Meng-Lund, H., Grohganz, Holger & Löbmann, Korbinian, 2019, In: Pharmaceutical Development and Technology. 24, 3, p. 323-328

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. 2018
  18. Published

    In situ co-amorphisation of arginine with indomethacin or furosemide during immersion in an acidic medium – A proof of concept study

    Petry, I., Löbmann, Korbinian, Grohganz, Holger, Rades, Thomas & Leopold, C. S., 1 Dec 2018, In: European Journal of Pharmaceutics and Biopharmaceutics. 133, p. 151-160 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Influence of preparation technique on co-amorphization of carvedilol with acidic amino acids

    Mishra, J., Löbmann, Korbinian, Grohganz, Holger & Rades, Thomas, 1 Dec 2018, In: International Journal of Pharmaceutics. 552, 1-2, p. 407-413

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    In vitro and in vivo comparison between crystalline and co-amorphous salts of naproxen-arginine

    Kasten, G., Lobo, L., Dengale, S., Grohganz, Holger, Rades, Thomas & Löbmann, Korbinian, 1 Nov 2018, In: European Journal of Pharmaceutics and Biopharmaceutics. 132, p. 192-199 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Aspartame as a co-former in co-amorphous systems

    Wu, W., Löbmann, Korbinian, Schnitzkewitz, J., Knuhtsen, A., Pedersen, D. S., Grohganz, Holger & Rades, Thomas, 5 Oct 2018, In: International Journal of Pharmaceutics. 549, 1-2, p. 380-387

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Organic acids as co-formers for co-amorphous systems - Influence of variation in molar ratio on the physicochemical properties of the co-amorphous systems

    Wu, W., Ueda, H., Lobmann, K., Rades, Thomas & Grohganz, Holger, Oct 2018, In: European Journal of Pharmaceutics and Biopharmaceutics. 131, p. 25-32

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    The Influence of Polymers on the Supersaturation Potential of Poor and Good Glass Formers

    Blaabjerg, L. I., Grohganz, Holger, Lindenberg, E., Löbmann, Korbinian, Mullertz, Anette & Rades, Thomas, 21 Sep 2018, In: Pharmaceutics. 10, 4, 14 p., 164.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    The Role of Glass Transition Temperatures in Coamorphous Drug-Amino Acid Formulations

    Kissi, E. O., Kasten, G., Löbmann, Korbinian, Rades, Thomas & Grohganz, Holger, 4 Sep 2018, In: Molecular Pharmaceutics. 15, 9, p. 4247–4256

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    The use of molecular descriptors in the development of co-amorphous formulations

    Meng-Lund, H. M. L., Korgaard, G. K., Jensen, K. B. T., Poso, A., Pantsar, T., Rades, Thomas, Rantanen, Jukka & Grohganz, Holger, 1 Jul 2018, In: European Journal of Pharmaceutical Sciences. 119, p. 31 38 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Application of a Salt Coformer in a Co-Amorphous Drug System Dramatically Enhances the Glass Transition Temperature: A Case Study of the Ternary System Carbamazepine, Citric Acid, and L-Arginine

    Ueda, H., Wu, W., Löbmann, Korbinian, Grohganz, Holger, Mullertz, Anette & Rades, Thomas, May 2018, In: Molecular Pharmaceutics. 15, 5, p. 2036-2044

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Influence of Solvent Composition on the Performance of Spray-Dried Co-Amorphous Formulations

    Mishra, J., Rades, Thomas, Löbmann, Korbinian & Grohganz, Holger, 12 Apr 2018, In: Pharmaceutics. 10, 2, p. 1-13

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Glass-Transition Temperature of the β-Relaxation as the Major Predictive Parameter for Recrystallization of Neat Amorphous Drugs

    Kissi, E. O., Grohganz, Holger, Löbmann, Korbinian, Ruggiero, M. T., Zeitler, J. A. & Rades, Thomas, 15 Mar 2018, In: Journal of Physical Chemistry Part B: Condensed Matter, Materials, Surfaces, Interfaces & Biophysical. 122, 10, p. 2803-2808 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 1421411