Christian Aalkjær

Christian Aalkjær

Emeritus

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    1. Published

      4-Aminopyridine: a pan voltage-gated potassium channel inhibitor that enhances K7.4 currents and inhibits noradrenaline-mediated contraction of rat mesenteric small arteries

      Khammy, M. M., Kim, S., Bentzen, Bo Hjorth, Lee, S., Choi, I., Aalkjær, Christian & Jepps, Thomas Andrew Qvistgaard, Feb 2018, In: British Journal of Pharmacology. 175, 3, p. 501-516 16 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    2. Published

      A model of smooth muscle cell synchronization in the arterial wall.

      Jacobsen, Jens Christian Brings, Aalkjær, Christian, Nilsson, H., Matchkov, V. V., Freiberg, J. & von Holstein-Rathlou, Niels-Henrik, 2007, In: American Journal of Physiology: Heart and Circulatory Physiology. 293, 1, p. H229-37

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      Abnormal neurovascular coupling as a cause of excess cerebral vasodilaion in familial migarine

      Staehr, C., Rajanathan, R., Postnov, D. D., Hangaard, L., Bouzinova, E., Lykke-Hartmann, K., Bach, F. W., Sandow, S. L., Aalkjær, Christian & Matchkov, V. V., 2020, In: Cardiovascular Research. 116, 12, p. 2009-2020 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      Activation of a cGMP-sensitive calcium-dependent chloride channel may cause transition from calcium waves to whole cell oscillations in smooth muscle cells.

      Jacobsen, Jens Christian Brings, Aalkjær, Christian, Nilsson, H., Matchkov, V. V., Freiberg, J. & von Holstein-Rathlou, Niels-Henrik, 2007, In: American Journal of Physiology: Heart and Circulatory Physiology. 293, 1, p. H215-28

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      Acute, pro-contractile effects of prorenin on rat mesenteric arteries

      Rognant, Salomé, Baldwin, S. N., Pritchard, H. A. T., Greenstein, A., Callø, Kirstine, Aalkjær, Christian & Jepps, Thomas Andrew Qvistgaard, 2023, In: FASEB Journal. 37, 12, 18 p., e23282.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      Brain capillary pericytes and neurovascular coupling

      Grubb, Søren, Lauritzen, Martin & Aalkjær, Christian, 2021, In: Comparative Biochemistry and Physiology - Part A: Molecular & Integrative Physiology. 254, 7 p., 110893.

      Research output: Contribution to journal › Review › Research › peer-review

    7. Published

      Colchicine enhances β adrenoceptor-mediated vasodilation in men with essential hypertension

      Ehlers, T. S., van der Horst, Jennifer, Møller, S., Piil, P. K., Gliemann, Lasse, Aalkjær, Christian, Jepps, Thomas Andrew Qvistgaard & Hellsten, Ylva, 2023, In: British Journal of Clinical Pharmacology. 89, 7, p. 2179-2189 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      Dynein coordinates β2-adrenoceptor-mediated relaxation in normotensive and hypertensive rat mesenteric arteries

      van der Horst, Jennifer, Rognant, Salomé, Hellsten, Ylva, Aalkjær, Christian & Jepps, Thomas Andrew Qvistgaard, 2022, In: Hypertension. 79, 10, p. 2214-2227 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Dynein regulates Kv7.4 channel trafficking from the cell membrane

      van der Horst, Jennifer, Rognant, Salomé, Abbott, G. W., Ozhathil, Lijo Cherian, Hägglund, Per Mårten, Barrese, V., Chuang, Christine, Jespersen, Thomas, Davies, Michael J., Greenwood, I. A., Gourdon, Pontus Emanuel, Aalkjær, Christian & Jepps, Thomas Andrew Qvistgaard, 2021, In: Journal of General Physiology. 153, 3, 19 p., e202012760.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      Extracellular Calcium-Dependent Modulation of Endothelium Relaxation in Rat Mesenteric Small Artery: The Role of Potassium Signaling

      Hangaard, L., Jessen, P. B., Kamaev, D., Aalkjær, Christian & Matchkov, V. V., 2015, In: BioMed Research International. 2015, p. 1-11 11 p., 758346.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      From pitfalls and pressures to culturing curiosity and creativity in early career physiologists

      Bailey, D. M., Fischer, Mads, Aalkjær, Christian & Secher, Niels H., 2023, In: The Physiological Society Magazine. 130, p. 11-11

      Research output: Contribution to journal › Comment/debate › Communication

    12. Published

      GLP-1 and its Analogue Liraglutide Affects Human Endothelial Cell Signaling by Reducing VEGF-A Induced Ca2+ Signaling and Activating Protein Kinases

      Rotbøl, C. E., Hansen, A., Tritsaris, Katerina, Xu, J., Aalkjær, Christian & Dissing, Steen, Apr 2015, In: F A S E B Journal. 29, 1 supplement, 1 p., 642.7.

      Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

    13. Published

      GLP-1 inhibits VEGFA-mediated signaling in isolated human endothelial cells and VEGFA-induced dilation of rat mesenteric arteries

      Rotbøl, C. E., Khammy, M. M., Dalsgaard, T., Mazur, A., Tritsaris, Katerina, Hansen, A. J., Aalkjær, Christian & Dissing, Steen, 1 Nov 2016, In: American Journal of Physiology: Heart and Circulatory Physiology. 311, 5, p. H1214-H1224

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      Heterogeneity and weak coupling may explain the synchronization characteristics of cells in the arterial wall.

      Jacobsen, Jens Christian Brings, Aalkjær, Christian, Matchkov, V. V., Nilsson, H., von Holstein-Rathlou, Niels-Henrik & Freiberg, J. J., 2008, In: Philosophical Transactions. Series A : Mathematical, physical, and engineering science. 366, 1880, p. 3483-502 19 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      Human lymphatic vessel contractile activity is inhibited in vitro but not in vivo by the calcium channel blocker nifedipine

      Telinius, N., Mohanakumar, S., Majgaard, J., Kim, S., Pilegaard, H., Pahle, E., Nielsen, J., de Leval, M., Aalkjær, Christian, Hjortdal, Vibeke Elisabeth & Boedtkjer, D. B., 1 Nov 2014, In: The Journal of Physiology. 592, 21, p. 4697-714 18 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      Human thoracic duct in vitro: diameter-tension properties, spontaneous and evoked contractile activity

      Telinius, N., Drewsen, N., Pilegaard, H., Kold-Petersen, H., de Leval, M., Aalkjær, Christian, Hjortdal, Vibeke Elisabeth & Boedtkjer, D. B., Sep 2010, In: A J P: Heart and Circulatory Physiology (Online). 299, 3, p. H811-8

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      Identification of novel proteins and mechanistic pathways associated with early-onset hypertension by deep proteomic mapping of resistance arteries

      Bastrup, Joakim Armstrong, Aalkjær, Christian & Jepps, Thomas Andrew Qvistgaard, 2022, In: Journal of Biological Chemistry. 298, 1, 17 p., 101512.

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      Increased NBCn1 expression, Na+/HCO- 3 co-transport and intracellular pH in human vascular smooth muscle cells with a risk allele for hypertension

      Ng, F. L., Boedtkjer, E., Witkowska, K., Ren, M., Zhang, R., Tucker, A., Aalkjær, Christian, Caulfield, M. J. & Ye, S., 2017, In: Human Molecular Genetics. 26, 5, p. 989-1002 14 p., ddx015.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      Intravital investigation of rat mesenteric small artery tone and blood flow

      Nyvad, J., Mazur, A., Postnov, D. D., Straarup, M. S., Soendergaard, A. M., Staehr, C., Brøndum, E., Aalkjær, Christian & Matchkov, V. V., 2017, In: Journal of Physiology. 595, 15, p. 5037-5053 17 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      Loss-of-activity-mutation in the cardiac chloride-bicarbonate exchanger AE3 causes short QT syndrome

      Thorsen, K., Dam, V. S., Kjaer-Sorensen, K., Pedersen, L. N., Skeberdis, V. A., Jurevicius, J., Treinys, R., Petersen, I. M. B. S., Nielsen, Morten Schak, Oxvig, C., Morth, J. P., Matchkov, V. V., Aalkjær, Christian, Bundgård, Henning & Jensen, H. K., 22 Nov 2017, In: Nature Communications. 8, 10 p., 1696.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      Maternal smoking and impaired endothelium-dependent nitric oxide-mediated relaxation of uterine small arteries in vitro

      Andersen, M. R., Uldbjerg, N., Stender, Steen, Sandager, K. P. & Aalkjær, Christian, 2011, In: American Journal of Obstetrics and Gynecology. 204, 2, p. 177.e1–177.e7

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      Mechanism and Consequence of Vasomotion

      Jacobsen, Jens Christian Brings & Aalkjær, Christian, 2021, Physics of Biological Oscillators: New Insights into Non-Equilibrium and Non-Autonomous Systems. Springer, p. 261-272 (Understanding Complex Systems).

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    23. Published

      Microtubule Regulation of Kv7 Channels Orchestrates cAMP-Mediated Vasorelaxations in Rat Arterial Smooth Muscle

      Lindman, J., Khammy, M. M., Lundegaard, Pia Rengtved, Aalkjær, Christian & Jepps, Thomas Andrew Qvistgaard, Feb 2018, In: Hypertension. 71, 2, p. 336-345 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      Migraine-Associated Mutation in the Na,K-ATPase Leads to Disturbances in Cardiac Metabolism and Reduced Cardiac Function

      Staehr, C., Rohde, P. D., Krarup, N. T., Ringgaard, S., Laustsen, C., Johnsen, J., Nielsen, R., Beck, H. C., Morth, J. P., Lykke-Hartmann, K., Jespersen, N. R., Abramochkin, D., Nyegaard, M., Botker, H. E., Aalkjær, Christian & Matchkov, V., 2022, In: Journal of the American Heart Association. 11, 7, 47 p., 021814.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      NBCn1 and NHE1 expression and activity in DeltaNErbB2 receptor-expressing MCF-7 breast cancer cells: contributions to pHi regulation and chemotherapy resistance

      Lauritzen, G., Jensen, M. B. F., Bødtkjer, E., Dybboe, R., Aalkjær, Christian, Nylandsted, J. & Pedersen, Stine Helene Falsig, 10 Sep 2010, In: Experimental Cell Research. 316, 15, p. 2538-53 16 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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