Christian Aalkjær
Emeritus
- 2007
- Published
A model of smooth muscle cell synchronization in the arterial wall.
Jacobsen, Jens Christian Brings, Aalkjær, Christian, Nilsson, H., Matchkov, V. V., Freiberg, J. & von Holstein-Rathlou, Niels-Henrik, 2007, In: American Journal of Physiology: Heart and Circulatory Physiology. 293, 1, p. H229-37Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Activation of a cGMP-sensitive calcium-dependent chloride channel may cause transition from calcium waves to whole cell oscillations in smooth muscle cells.
Jacobsen, Jens Christian Brings, Aalkjær, Christian, Nilsson, H., Matchkov, V. V., Freiberg, J. & von Holstein-Rathlou, Niels-Henrik, 2007, In: American Journal of Physiology: Heart and Circulatory Physiology. 293, 1, p. H215-28Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Variable involvement of the perivascular retinal tissue in carbonic anhydrase inhibitor induced relaxation of porcine retinal arterioles in vitro.
Kehler, A. K., Holmgaard, K., Hessellund, A., Aalkjær, Christian, Bek, T. & Toft-Kehler, A. K., 1 Oct 2007, In: Investigative Ophthalmology & Visual Science. 48, 10, p. 4688-4693 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2008
- Published
Heterogeneity and weak coupling may explain the synchronization characteristics of cells in the arterial wall.
Jacobsen, Jens Christian Brings, Aalkjær, Christian, Matchkov, V. V., Nilsson, H., von Holstein-Rathlou, Niels-Henrik & Freiberg, J. J., 2008, In: Philosophical Transactions. Series A : Mathematical, physical, and engineering science. 366, 1880, p. 3483-502 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2009
- Published
Smoking cessation early in pregnancy and birth weight, length, head circumference, and endothelial nitric oxide synthase activity in umbilical and chorionic vessels: an observational study of healthy singleton pregnancies
Andersen, M. R., Simonsen, U., Uldbjerg, N., Stender, Steen & Aalkjær, Christian, 2009, In: Circulation. 119, 6, p. 857-64 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2010
- Published
Human thoracic duct in vitro: diameter-tension properties, spontaneous and evoked contractile activity
Telinius, N., Drewsen, N., Pilegaard, H., Kold-Petersen, H., de Leval, M., Aalkjær, Christian, Hjortdal, Vibeke Elisabeth & Boedtkjer, D. B., Sep 2010, In: A J P: Heart and Circulatory Physiology (Online). 299, 3, p. H811-8Research output: Contribution to journal › Journal article › Research › peer-review
- Published
NBCn1 and NHE1 expression and activity in DeltaNErbB2 receptor-expressing MCF-7 breast cancer cells: contributions to pHi regulation and chemotherapy resistance
Lauritzen, G., Jensen, M. B. F., Bødtkjer, E., Dybboe, R., Aalkjær, Christian, Nylandsted, J. & Pedersen, Stine Helene Falsig, 10 Sep 2010, In: Experimental Cell Research. 316, 15, p. 2538-53 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2011
- Published
Maternal smoking and impaired endothelium-dependent nitric oxide-mediated relaxation of uterine small arteries in vitro
Andersen, M. R., Uldbjerg, N., Stender, Steen, Sandager, K. P. & Aalkjær, Christian, 2011, In: American Journal of Obstetrics and Gynecology. 204, 2, p. 177.e1–177.e7Research output: Contribution to journal › Journal article › Research › peer-review
- 2012
NHE1 knockout reduces blood pressure and arterial media/lumen ratio with no effect on resting pH(i) in the vascular wall
Boedtkjer, E., Damkier, H. H. & Aalkjær, Christian, 15 Apr 2012, In: The Journal of Physiology. 590, Pt 8, p. 1895-906 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2013
- Published
Protection against high intravascular pressure in giraffe legs
Petersen, K. K., Hørlyck, A., Østergaard, K. H., Andresen, J., Brøgger, T. H., Jensen, N. S., Telinius, N., Laher, I., Bertelsen, Mads Frost, Grøndahl, C., Smerup, M. H., Secher, Niels H., Brøndum, E. T., Hasenkam, J. M., Wang, T., Baandrup, U. & Aalkjær, Christian, 2013, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 305, 9, p. R1021-R1030 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
- Published
The human thoracic duct is functionally innervated by adrenergic nerves
Telinius, N., Baandrup, U., Rumessen, J., Pilegaard, H., Hjortdal, Vibeke Elisabeth, Aalkjær, Christian & Boedtkjer, D. B., 15 Jan 2014, In: A J P: Heart and Circulatory Physiology (Online). 306, 2, p. H206-13Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The contribution of K(+) channels to human thoracic duct contractility
Telinius, N., Kim, S., Pilegaard, H., Pahle, E., Nielsen, J., Hjortdal, Vibeke Elisabeth, Aalkjær, Christian & Boedtkjer, D. B., 1 Jul 2014, In: A J P: Heart and Circulatory Physiology (Online). 307, 1, p. H33-43Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human lymphatic vessel contractile activity is inhibited in vitro but not in vivo by the calcium channel blocker nifedipine
Telinius, N., Mohanakumar, S., Majgaard, J., Kim, S., Pilegaard, H., Pahle, E., Nielsen, J., de Leval, M., Aalkjær, Christian, Hjortdal, Vibeke Elisabeth & Boedtkjer, D. B., 1 Nov 2014, In: The Journal of Physiology. 592, 21, p. 4697-714 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
- Published
Extracellular Calcium-Dependent Modulation of Endothelium Relaxation in Rat Mesenteric Small Artery: The Role of Potassium Signaling
Hangaard, L., Jessen, P. B., Kamaev, D., Aalkjær, Christian & Matchkov, V. V., 2015, In: BioMed Research International. 2015, p. 1-11 11 p., 758346.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The giraffe kidney tolerates high arterial blood pressure by high renal interstitial pressure and low glomerular filtration rate
Damkjær, M., Wang, T., Brøndum, E., Østergaard, K. H., Baandrup, U., Hørlyck, A., Hasenkam, J. M., Smerup, M., Funder, J., Marcussen, N., Danielsen, C. C., Bertelsen, Mads Frost, Grøndahl, C., Pedersen, M., Agger, P., Candy, G., Aalkjær, Christian & Bie, P., 2015, In: Acta Physiologica (Print). 214, 4, p. 497-510 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP-1 and its Analogue Liraglutide Affects Human Endothelial Cell Signaling by Reducing VEGF-A Induced Ca2+ Signaling and Activating Protein Kinases
Rotbøl, C. E., Hansen, A., Tritsaris, Katerina, Xu, J., Aalkjær, Christian & Dissing, Steen, Apr 2015, In: F A S E B Journal. 29, 1 supplement, 1 p., 642.7.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Role of peripheral vascular resistance for the association between major depression and cardiovascular disease
Bouzinova, E. V., Wiborg, O., Aalkjær, Christian & Matchkov, V. V., Apr 2015, In: Journal of Cardiovascular Pharmacology. 65, 4, p. 299-307 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Voltage-gated sodium channels contribute to action potentials and spontaneous contractility in isolated human lymphatic vessels
Telinius, N., Majgaard, J., Kim, S., Katballe, N., Pahle, E., Nielsen, J., Hjortdal, Vibeke Elisabeth, Aalkjær, Christian & Boedtkjer, D. B., 15 Jul 2015, In: The Journal of Physiology. 593, 14, p. 3109-22 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
- Published
The thick left ventricular wall of the giraffe heart normalises wall tension, but limits stroke volume and cardiac output
Smerup, M., Damkjær, M., Brøndum, E. T., Baandrup, U. T., Kristiansen, S. B., Nygaard, H., Funder, J. A., Aalkjær, Christian, Sauer, C., Buchanan, R., Bertelsen, Mads Frost, Østergaard, K. H., Grøndahl, C., Candy, G., Hasenkam, J. M., Secher, Niels H., Bie, P. & Wang, T., 2016, In: The Journal of Experimental Biology. 219, 3, p. 457-463 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Negative News: Cl- and HCO3- in the Vascular Wall
Bødtkjer, E., Matchkov, V. V., Boedtkjer, D. M. B. & Aalkjær, Christian, Sep 2016, In: Physiology. 31, 5, p. 370-383 14 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
GLP-1 inhibits VEGFA-mediated signaling in isolated human endothelial cells and VEGFA-induced dilation of rat mesenteric arteries
Rotbøl, C. E., Khammy, M. M., Dalsgaard, T., Mazur, A., Tritsaris, Katerina, Hansen, A. J., Aalkjær, Christian & Dissing, Steen, 1 Nov 2016, In: American Journal of Physiology: Heart and Circulatory Physiology. 311, 5, p. H1214-H1224Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
Increased NBCn1 expression, Na+/HCO- 3 co-transport and intracellular pH in human vascular smooth muscle cells with a risk allele for hypertension
Ng, F. L., Boedtkjer, E., Witkowska, K., Ren, M., Zhang, R., Tucker, A., Aalkjær, Christian, Caulfield, M. J. & Ye, S., 2017, In: Human Molecular Genetics. 26, 5, p. 989-1002 14 p., ddx015.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Intravital investigation of rat mesenteric small artery tone and blood flow
Nyvad, J., Mazur, A., Postnov, D. D., Straarup, M. S., Soendergaard, A. M., Staehr, C., Brøndum, E., Aalkjær, Christian & Matchkov, V. V., 2017, In: Journal of Physiology. 595, 15, p. 5037-5053 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
Spontaneous and Evoked Contractility of Human Intestinal Lymphatic Vessels
Telinius, N., Majgaard, J., Mohanakumar, S., Pahle, E., Nielsen, J., Hjortdal, Vibeke Elisabeth, Aalkjær, Christian & Boedtkjer, D. B., Mar 2017, In: Lymphatic Research and Biology. 15, 1, p. 17-22 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Na-K-ATPase regulates intercellular communication in the vascular wall via CSRC Kinase-Dependent connexin43 phosphorylation
Hangaard, L., Bouzinova, E. V., Staehr, C., Dam, V. S., Kim, S., Xie, Z., Aalkjær, Christian & Matchkov, V. V., Apr 2017, In: American Journal of Physiology - Cell Physiology. 312, 4, p. C385-C397Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Phosphodiesterase 1a inhibition elicits cGMP-dependent relaxation of rat mesenteric arteries
Khammy, M. M., Dalsgaard, T., Larsen, P. H., Christoffersen, C. T., Clausen, D., Rasmussen, L. K., Folkersen, L., Grunnet, Morten, Kehler, J., Aalkjær, Christian & Nielsen, J., Nov 2017, In: British Journal of Pharmacology. 174, 22, p. 4186-4198 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Loss-of-activity-mutation in the cardiac chloride-bicarbonate exchanger AE3 causes short QT syndrome
Thorsen, K., Dam, V. S., Kjaer-Sorensen, K., Pedersen, L. N., Skeberdis, V. A., Jurevicius, J., Treinys, R., Petersen, I. M. B. S., Nielsen, Morten Schak, Oxvig, C., Morth, J. P., Matchkov, V. V., Aalkjær, Christian, Bundgård, Henning & Jensen, H. K., 22 Nov 2017, In: Nature Communications. 8, 10 p., 1696.Research output: Contribution to journal › Journal article › Research › peer-review
- 2018
- Published
4-Aminopyridine: a pan voltage-gated potassium channel inhibitor that enhances K7.4 currents and inhibits noradrenaline-mediated contraction of rat mesenteric small arteries
Khammy, M. M., Kim, S., Bentzen, Bo Hjorth, Lee, S., Choi, I., Aalkjær, Christian & Jepps, Thomas Andrew Qvistgaard, Feb 2018, In: British Journal of Pharmacology. 175, 3, p. 501-516 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Microtubule Regulation of Kv7 Channels Orchestrates cAMP-Mediated Vasorelaxations in Rat Arterial Smooth Muscle
Lindman, J., Khammy, M. M., Lundegaard, Pia Rengtved, Aalkjær, Christian & Jepps, Thomas Andrew Qvistgaard, Feb 2018, In: Hypertension. 71, 2, p. 336-345 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
Perivascular Adipose Tissue Contributes to the Modulation of Vascular Tone in vivo
Saxton, S. N., Withers, S. B., Nyvad, J., Mazur, A., Matchkov, V., Heagerty, A. M. & Aalkjær, Christian, 2019, In: Journal of Vascular Research. 56, 6, p. 320-332Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rat mesenteric small artery neurogenic dilatation is predominantly mediated by beta(1)-adrenoceptors in vivo
Sondergaard, A. M., Overgaard, C. B., Mazur, A., Postnov, D. D., Matchkov, V. V. & Aalkjær, Christian, 2019, In: The Journal of Physiology. 597, 7, p. 1819-1831Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
Abnormal neurovascular coupling as a cause of excess cerebral vasodilaion in familial migarine
Staehr, C., Rajanathan, R., Postnov, D. D., Hangaard, L., Bouzinova, E., Lykke-Hartmann, K., Bach, F. W., Sandow, S. L., Aalkjær, Christian & Matchkov, V. V., 2020, In: Cardiovascular Research. 116, 12, p. 2009-2020 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
Brain capillary pericytes and neurovascular coupling
Grubb, Søren, Lauritzen, Martin & Aalkjær, Christian, 2021, In: Comparative Biochemistry and Physiology - Part A: Molecular & Integrative Physiology. 254, 7 p., 110893.Research output: Contribution to journal › Review › Research › peer-review
- Published
Dynein regulates Kv7.4 channel trafficking from the cell membrane
van der Horst, Jennifer, Rognant, Salomé, Abbott, G. W., Ozhathil, Lijo Cherian, Hägglund, Per Mårten, Barrese, V., Chuang, Christine, Jespersen, Thomas, Davies, Michael J., Greenwood, I. A., Gourdon, Pontus Emanuel, Aalkjær, Christian & Jepps, Thomas Andrew Qvistgaard, 2021, In: Journal of General Physiology. 153, 3, 19 p., e202012760.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mechanism and Consequence of Vasomotion
Jacobsen, Jens Christian Brings & Aalkjær, Christian, 2021, Physics of Biological Oscillators: New Insights into Non-Equilibrium and Non-Autonomous Systems. Springer, p. 261-272 (Understanding Complex Systems).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
The Remarkable Cardiovascular System of Giraffes
Aalkjær, Christian & Wang, T., 2021, In: Annual Review of Physiology. 83, p. 1-15Research output: Contribution to journal › Review › Research › peer-review
- 2022
- Published
Dynein coordinates β2-adrenoceptor-mediated relaxation in normotensive and hypertensive rat mesenteric arteries
van der Horst, Jennifer, Rognant, Salomé, Hellsten, Ylva, Aalkjær, Christian & Jepps, Thomas Andrew Qvistgaard, 2022, In: Hypertension. 79, 10, p. 2214-2227 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of novel proteins and mechanistic pathways associated with early-onset hypertension by deep proteomic mapping of resistance arteries
Bastrup, Joakim Armstrong, Aalkjær, Christian & Jepps, Thomas Andrew Qvistgaard, 2022, In: Journal of Biological Chemistry. 298, 1, 17 p., 101512.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Migraine-Associated Mutation in the Na,K-ATPase Leads to Disturbances in Cardiac Metabolism and Reduced Cardiac Function
Staehr, C., Rohde, P. D., Krarup, N. T., Ringgaard, S., Laustsen, C., Johnsen, J., Nielsen, R., Beck, H. C., Morth, J. P., Lykke-Hartmann, K., Jespersen, N. R., Abramochkin, D., Nyegaard, M., Botker, H. E., Aalkjær, Christian & Matchkov, V., 2022, In: Journal of the American Heart Association. 11, 7, 47 p., 021814.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
No guidelines for vascular nerves?
De Mey, J. G. R., Simonsen, U. & Aalkjær, Christian, 2022, In: American Journal of Physiology - Heart and Circulatory Physiology. 322, 4, p. H681-H682Research output: Contribution to journal › Letter › Research › peer-review
- Published
The microtubule network enables Src kinase interaction with the Na,K-ATPase to generate Ca2+ flashes in smooth muscle cells
Rognant, Salomé, Kravtsova, V. V., Bouzinova, E. V., Melnikova, E. V., Krivoi, I. I., Pierre, S. V., Aalkjær, Christian, Jepps, Thomas Andrew Qvistgaard & Matchkov, V. V., 2022, In: Frontiers in Physiology. 13, 14 p., 1007340.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The solution to bicarbonate
Boedtkjer, E. & Aalkjær, Christian, 2022, In: American Journal of Physiology - Heart and Circulatory Physiology. 322, 4, p. H685-H686Research output: Contribution to journal › Letter › Research › peer-review
- 2023
- Published
Acute, pro-contractile effects of prorenin on rat mesenteric arteries
Rognant, Salomé, Baldwin, S. N., Pritchard, H. A. T., Greenstein, A., Callø, Kirstine, Aalkjær, Christian & Jepps, Thomas Andrew Qvistgaard, 2023, In: FASEB Journal. 37, 12, 18 p., e23282.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Colchicine enhances β adrenoceptor-mediated vasodilation in men with essential hypertension
Ehlers, T. S., van der Horst, Jennifer, Møller, S., Piil, P. K., Gliemann, Lasse, Aalkjær, Christian, Jepps, Thomas Andrew Qvistgaard & Hellsten, Ylva, 2023, In: British Journal of Clinical Pharmacology. 89, 7, p. 2179-2189 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
From pitfalls and pressures to culturing curiosity and creativity in early career physiologists
Bailey, D. M., Fischer, Mads, Aalkjær, Christian & Secher, Niels H., 2023, In: The Physiological Society Magazine. 130, p. 11-11Research output: Contribution to journal › Comment/debate › Communication
- Published
Professor Niels Henry Secher: Celebrating success from boat to bench to bedside
Aalkjær, Christian, Fischer, Mads & Bailey, D. M., 2023, In: Experimental Physiology. 108, 10, p. 1233-1234Research output: Contribution to journal › Journal article › Communication
- Published
The cardiovascular challenges in giraffes
Aalkjær, Christian & Wang, T., 2023, In: Journal of Muscle Research and Cell Motility. 44, p. 53–60 8 p.Research output: Contribution to journal › Review › Research › peer-review
ID: 40980311
Most downloads
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240
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Loss-of-activity-mutation in the cardiac chloride-bicarbonate exchanger AE3 causes short QT syndrome
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
208
downloads
Increased NBCn1 expression, Na+/HCO- 3 co-transport and intracellular pH in human vascular smooth muscle cells with a risk allele for hypertension
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
36
downloads
Dynein regulates Kv7.4 channel trafficking from the cell membrane
Research output: Contribution to journal › Journal article › Research › peer-review
Published