Zebrafish as A Model for Fish Diseases in Aquaculture
Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt
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Zebrafish as A Model for Fish Diseases in Aquaculture. / Jørgensen, Louise von Gersdorff.
I: Pathogens, Bind 9, Nr. 8, 609, 2020.Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt
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TY - JOUR
T1 - Zebrafish as A Model for Fish Diseases in Aquaculture
AU - Jørgensen, Louise von Gersdorff
PY - 2020
Y1 - 2020
N2 - The use of zebrafish as a model for human conditions is widely recognized. Within the last couple of decades, the zebrafish has furthermore increasingly been utilized as a model for diseases in aquacultured fish species. The unique tools available in zebrafish present advantages compared to other animal models and unprecedented in vivo imaging and the use of transgenic zebrafish lines have contributed with novel knowledge to this field. In this review, investigations conducted in zebrafish on economically important diseases in aquacultured fish species are included. Studies are summarized on bacterial, viral and parasitic diseases and described in relation to prophylactic approaches, immunology and infection biology. Considerable attention has been assigned to innate and adaptive immunological responses. Finally, advantages and drawbacks of using the zebrafish as a model for aquacultured fish species are discussed
AB - The use of zebrafish as a model for human conditions is widely recognized. Within the last couple of decades, the zebrafish has furthermore increasingly been utilized as a model for diseases in aquacultured fish species. The unique tools available in zebrafish present advantages compared to other animal models and unprecedented in vivo imaging and the use of transgenic zebrafish lines have contributed with novel knowledge to this field. In this review, investigations conducted in zebrafish on economically important diseases in aquacultured fish species are included. Studies are summarized on bacterial, viral and parasitic diseases and described in relation to prophylactic approaches, immunology and infection biology. Considerable attention has been assigned to innate and adaptive immunological responses. Finally, advantages and drawbacks of using the zebrafish as a model for aquacultured fish species are discussed
U2 - 10.3390/pathogens9080609
DO - 10.3390/pathogens9080609
M3 - Review
C2 - 32726918
VL - 9
JO - Pathogens
JF - Pathogens
SN - 2076-0817
IS - 8
M1 - 609
ER -
ID: 242653390