Xerosis is Associated with Atopic Dermatitis, Hand Eczema and Contact Sensitization Independent of Filaggrin Gene Mutations

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Standard

Xerosis is Associated with Atopic Dermatitis, Hand Eczema and Contact Sensitization Independent of Filaggrin Gene Mutations. / Thyssen, Jacob P; Johansen, Jeanne D; Zachariae, Claus; Menné, Torkil; Linneberg, Allan.

I: Acta Dermatovenereologica, 2013.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Thyssen, JP, Johansen, JD, Zachariae, C, Menné, T & Linneberg, A 2013, 'Xerosis is Associated with Atopic Dermatitis, Hand Eczema and Contact Sensitization Independent of Filaggrin Gene Mutations', Acta Dermatovenereologica. https://doi.org/10.2340/00015555-1539

APA

Thyssen, J. P., Johansen, J. D., Zachariae, C., Menné, T., & Linneberg, A. (2013). Xerosis is Associated with Atopic Dermatitis, Hand Eczema and Contact Sensitization Independent of Filaggrin Gene Mutations. Acta Dermatovenereologica. https://doi.org/10.2340/00015555-1539

Vancouver

Thyssen JP, Johansen JD, Zachariae C, Menné T, Linneberg A. Xerosis is Associated with Atopic Dermatitis, Hand Eczema and Contact Sensitization Independent of Filaggrin Gene Mutations. Acta Dermatovenereologica. 2013. https://doi.org/10.2340/00015555-1539

Author

Thyssen, Jacob P ; Johansen, Jeanne D ; Zachariae, Claus ; Menné, Torkil ; Linneberg, Allan. / Xerosis is Associated with Atopic Dermatitis, Hand Eczema and Contact Sensitization Independent of Filaggrin Gene Mutations. I: Acta Dermatovenereologica. 2013.

Bibtex

@article{eeb52d6a139243dc8aaabd09500bf3a8,
title = "Xerosis is Associated with Atopic Dermatitis, Hand Eczema and Contact Sensitization Independent of Filaggrin Gene Mutations",
abstract = "Atopic dermatitis, hand eczema and contact sensitization are prevalent disorders, and may, in many cases, be secondary to skin barrier abnormality. The aim of this study was to investigate the association between self-reported generalized xerosis, atopic dermatitis, hand eczema and contact sensitization, taking filaggrin gene mutations into account. Questionnaire data were collected from a cross-sectional study performed in a general population in Copenhagen. A total of 3,460 18-69-year-olds were patch-tested and 3,335 were genotyped for the 2282del4 and R501X mutations in the filaggrin gene. Atopic dermatitis and hand eczema were significantly associated with generalized xerosis, whereas contact sensitization (not nickel) showed only a borderline significant association. These results suggest that generalized xerosis may increase the risk of common skin disorders.",
author = "Thyssen, {Jacob P} and Johansen, {Jeanne D} and Claus Zachariae and Torkil Menn{\'e} and Allan Linneberg",
year = "2013",
doi = "10.2340/00015555-1539",
language = "English",
journal = "Acta Dermato-Venereologica",
issn = "0001-5555",
publisher = "Society for the Publication of Acta Dermato - Venereologica",

}

RIS

TY - JOUR

T1 - Xerosis is Associated with Atopic Dermatitis, Hand Eczema and Contact Sensitization Independent of Filaggrin Gene Mutations

AU - Thyssen, Jacob P

AU - Johansen, Jeanne D

AU - Zachariae, Claus

AU - Menné, Torkil

AU - Linneberg, Allan

PY - 2013

Y1 - 2013

N2 - Atopic dermatitis, hand eczema and contact sensitization are prevalent disorders, and may, in many cases, be secondary to skin barrier abnormality. The aim of this study was to investigate the association between self-reported generalized xerosis, atopic dermatitis, hand eczema and contact sensitization, taking filaggrin gene mutations into account. Questionnaire data were collected from a cross-sectional study performed in a general population in Copenhagen. A total of 3,460 18-69-year-olds were patch-tested and 3,335 were genotyped for the 2282del4 and R501X mutations in the filaggrin gene. Atopic dermatitis and hand eczema were significantly associated with generalized xerosis, whereas contact sensitization (not nickel) showed only a borderline significant association. These results suggest that generalized xerosis may increase the risk of common skin disorders.

AB - Atopic dermatitis, hand eczema and contact sensitization are prevalent disorders, and may, in many cases, be secondary to skin barrier abnormality. The aim of this study was to investigate the association between self-reported generalized xerosis, atopic dermatitis, hand eczema and contact sensitization, taking filaggrin gene mutations into account. Questionnaire data were collected from a cross-sectional study performed in a general population in Copenhagen. A total of 3,460 18-69-year-olds were patch-tested and 3,335 were genotyped for the 2282del4 and R501X mutations in the filaggrin gene. Atopic dermatitis and hand eczema were significantly associated with generalized xerosis, whereas contact sensitization (not nickel) showed only a borderline significant association. These results suggest that generalized xerosis may increase the risk of common skin disorders.

U2 - 10.2340/00015555-1539

DO - 10.2340/00015555-1539

M3 - Journal article

C2 - 23420336

JO - Acta Dermato-Venereologica

JF - Acta Dermato-Venereologica

SN - 0001-5555

ER -

ID: 48481149