Ultrasound of Subtalar Joint Synovitis in Patients with Rheumatoid Arthritis: Results of an OMERACT Reliability Exercise Using Consensual Definitions
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Ultrasound of Subtalar Joint Synovitis in Patients with Rheumatoid Arthritis : Results of an OMERACT Reliability Exercise Using Consensual Definitions. / Bruyn, George A W; Siddle, Heidi J; Hanova, Petra; Costantino, Félicie; Iagnocco, Annamaria; Sedie, Andrea Delle; Gutierrez, Marwin; Hammer, Hilde B; Jernberg, Elizabeth; Loeille, Damien; Micu, Mihaela C; Moller, Ingrid; Pineda, Carlos; Richards, Bethan; Stoenoiu, Maria S; Suzuki, Takeshi; Terslev, Lene; Vlad, Violeta; Wonink, Robert; d'Agostino, Maria-Antonietta; Wakefield, Richard J.
I: Journal of Rheumatology, Bind 46, Nr. 4, 2019, s. 351-359.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Ultrasound of Subtalar Joint Synovitis in Patients with Rheumatoid Arthritis
T2 - Results of an OMERACT Reliability Exercise Using Consensual Definitions
AU - Bruyn, George A W
AU - Siddle, Heidi J
AU - Hanova, Petra
AU - Costantino, Félicie
AU - Iagnocco, Annamaria
AU - Sedie, Andrea Delle
AU - Gutierrez, Marwin
AU - Hammer, Hilde B
AU - Jernberg, Elizabeth
AU - Loeille, Damien
AU - Micu, Mihaela C
AU - Moller, Ingrid
AU - Pineda, Carlos
AU - Richards, Bethan
AU - Stoenoiu, Maria S
AU - Suzuki, Takeshi
AU - Terslev, Lene
AU - Vlad, Violeta
AU - Wonink, Robert
AU - d'Agostino, Maria-Antonietta
AU - Wakefield, Richard J
PY - 2019
Y1 - 2019
N2 - OBJECTIVE: To evaluate the intraobserver and interobserver reliability of the ultrasonographic (US) assessment of subtalar joint (STJ) synovitis in patients with rheumatoid arthritis (RA).METHODS: Following a Delphi process, 12 sonographers conducted an US reliability exercise on 10 RA patients with hindfoot pain. The anteromedial, posteromedial, and posterolateral STJ was assessed using B-mode and power Doppler (PD) techniques according to an agreed US protocol and using a 4-grade semiquantitative grading score for synovitis [synovial hypertrophy (SH) and signal] and a dichotomous score for the presence of joint effusion (JE). Intraobserver and interobserver reliability were computed by Cohen's and Light's κ. Weighted κ coefficients with absolute weighting were computed for B-mode and PD signal.RESULTS: Mean weighted Cohen's κ for SH, PD, and JE were 0.80 (95% CI 0.62-0.98), 0.61 (95% CI 0.48-0.73), and 0.52 (95% CI 0.36-0.67), respectively. Weighted Cohen's κ for SH, PD, and JE in the anteromedial, posteromedial, and posterolateral STJ were -0.04 to 0.79, 0.42-0.95, and 0.28-0.77; 0.31-1, -0.05 to 0.65, and -0.2 to 0.69; 0.66-1, 0.52-1, and 0.42-0.88, respectively. Weighted Light's κ for SH was 0.67 (95% CI 0.58-0.74), 0.46 (95% CI 0.35-0.59) for PD, and 0.16 (95% CI 0.08-0.27) for JE. Weighted Light's κ for SH, PD, and JE were 0.63 (95% CI 0.45-0.82), 0.33 (95% CI 0.19-0.42), and 0.09 (95% CI -0.01 to 0.19), for the anteromedial; 0.49 (95% CI 0.27-0.64), 0.35 (95% CI 0.27-0.4), and 0.04 (95% CI -0.06 to 0.1) for posteromedial; and 0.82 (95% CI 0.75-0.89), 0.66 (95% CI 0.56-0.8), and 0.18 (95% CI 0.04-0.34) for posterolateral STJ, respectively.CONCLUSION: Using a multisite assessment, US appears to be a reliable tool for assessing synovitis of STJ in RA.
AB - OBJECTIVE: To evaluate the intraobserver and interobserver reliability of the ultrasonographic (US) assessment of subtalar joint (STJ) synovitis in patients with rheumatoid arthritis (RA).METHODS: Following a Delphi process, 12 sonographers conducted an US reliability exercise on 10 RA patients with hindfoot pain. The anteromedial, posteromedial, and posterolateral STJ was assessed using B-mode and power Doppler (PD) techniques according to an agreed US protocol and using a 4-grade semiquantitative grading score for synovitis [synovial hypertrophy (SH) and signal] and a dichotomous score for the presence of joint effusion (JE). Intraobserver and interobserver reliability were computed by Cohen's and Light's κ. Weighted κ coefficients with absolute weighting were computed for B-mode and PD signal.RESULTS: Mean weighted Cohen's κ for SH, PD, and JE were 0.80 (95% CI 0.62-0.98), 0.61 (95% CI 0.48-0.73), and 0.52 (95% CI 0.36-0.67), respectively. Weighted Cohen's κ for SH, PD, and JE in the anteromedial, posteromedial, and posterolateral STJ were -0.04 to 0.79, 0.42-0.95, and 0.28-0.77; 0.31-1, -0.05 to 0.65, and -0.2 to 0.69; 0.66-1, 0.52-1, and 0.42-0.88, respectively. Weighted Light's κ for SH was 0.67 (95% CI 0.58-0.74), 0.46 (95% CI 0.35-0.59) for PD, and 0.16 (95% CI 0.08-0.27) for JE. Weighted Light's κ for SH, PD, and JE were 0.63 (95% CI 0.45-0.82), 0.33 (95% CI 0.19-0.42), and 0.09 (95% CI -0.01 to 0.19), for the anteromedial; 0.49 (95% CI 0.27-0.64), 0.35 (95% CI 0.27-0.4), and 0.04 (95% CI -0.06 to 0.1) for posteromedial; and 0.82 (95% CI 0.75-0.89), 0.66 (95% CI 0.56-0.8), and 0.18 (95% CI 0.04-0.34) for posterolateral STJ, respectively.CONCLUSION: Using a multisite assessment, US appears to be a reliable tool for assessing synovitis of STJ in RA.
U2 - 10.3899/jrheum.171490
DO - 10.3899/jrheum.171490
M3 - Journal article
C2 - 30385707
VL - 46
SP - 351
EP - 359
JO - Journal of Rheumatology
JF - Journal of Rheumatology
SN - 0315-162X
IS - 4
ER -
ID: 241011558