Two intestinal specific nuclear factors binding to the lactase-phlorizin hydrolase and sucrase-isomaltase promoters are functionally related oligomeric molecules.

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Standard

Two intestinal specific nuclear factors binding to the lactase-phlorizin hydrolase and sucrase-isomaltase promoters are functionally related oligomeric molecules. / Troelsen, J T; Mitchelmore, C; Sjöström, H; Norén, O; Olsen, Jørgen; Hansen, Gert Helge.

I: FEBS Letters, Bind 342, Nr. 3, 1994, s. 297-301.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Troelsen, JT, Mitchelmore, C, Sjöström, H, Norén, O, Olsen, J & Hansen, GH 1994, 'Two intestinal specific nuclear factors binding to the lactase-phlorizin hydrolase and sucrase-isomaltase promoters are functionally related oligomeric molecules.', FEBS Letters, bind 342, nr. 3, s. 297-301.

APA

Troelsen, J. T., Mitchelmore, C., Sjöström, H., Norén, O., Olsen, J., & Hansen, G. H. (1994). Two intestinal specific nuclear factors binding to the lactase-phlorizin hydrolase and sucrase-isomaltase promoters are functionally related oligomeric molecules. FEBS Letters, 342(3), 297-301.

Vancouver

Troelsen JT, Mitchelmore C, Sjöström H, Norén O, Olsen J, Hansen GH. Two intestinal specific nuclear factors binding to the lactase-phlorizin hydrolase and sucrase-isomaltase promoters are functionally related oligomeric molecules. FEBS Letters. 1994;342(3):297-301.

Author

Troelsen, J T ; Mitchelmore, C ; Sjöström, H ; Norén, O ; Olsen, Jørgen ; Hansen, Gert Helge. / Two intestinal specific nuclear factors binding to the lactase-phlorizin hydrolase and sucrase-isomaltase promoters are functionally related oligomeric molecules. I: FEBS Letters. 1994 ; Bind 342, Nr. 3. s. 297-301.

Bibtex

@article{8c81f0f099fb11dd86a6000ea68e967b,
title = "Two intestinal specific nuclear factors binding to the lactase-phlorizin hydrolase and sucrase-isomaltase promoters are functionally related oligomeric molecules.",
abstract = "Lactase-phlorizin hydrolase (LPH) and sucrase-isomaltase (SI) are enterocyte-specific gene products. The identification of regulatory cis-elements in the promoter of these two genes has enabled us to carry out comparative studies of the corresponding intestinal-specific nuclear factors (NF-LPH1 and SIF1-BP). Electrophoretic mobility shift assays demonstrated that the two nuclear factors compete for binding on the same cis-elements. The molecular size of the DNA binding polypeptide is estimated to be approximately 50 kDa for both factors. In the native form the factors are found as 250 kDa oligomeric complexes. Based on these results NF-LPH1 and SIF1-BP are suggested to be either identical or closely related molecules.",
author = "Troelsen, {J T} and C Mitchelmore and H Sj{\"o}str{\"o}m and O Nor{\'e}n and J{\o}rgen Olsen and Hansen, {Gert Helge}",
note = "Keywords: Base Sequence; Cell Line; DNA-Binding Proteins; Gene Expression Regulation; Glycosylceramidase; Humans; Molecular Sequence Data; Molecular Weight; Nuclear Proteins; Oligodeoxyribonucleotides; Promoter Regions (Genetics); RNA, Messenger; Sucrase-Isomaltase Complex; Transcription Factors",
year = "1994",
language = "English",
volume = "342",
pages = "297--301",
journal = "F E B S Letters",
issn = "0014-5793",
publisher = "JohnWiley & Sons Ltd",
number = "3",

}

RIS

TY - JOUR

T1 - Two intestinal specific nuclear factors binding to the lactase-phlorizin hydrolase and sucrase-isomaltase promoters are functionally related oligomeric molecules.

AU - Troelsen, J T

AU - Mitchelmore, C

AU - Sjöström, H

AU - Norén, O

AU - Olsen, Jørgen

AU - Hansen, Gert Helge

N1 - Keywords: Base Sequence; Cell Line; DNA-Binding Proteins; Gene Expression Regulation; Glycosylceramidase; Humans; Molecular Sequence Data; Molecular Weight; Nuclear Proteins; Oligodeoxyribonucleotides; Promoter Regions (Genetics); RNA, Messenger; Sucrase-Isomaltase Complex; Transcription Factors

PY - 1994

Y1 - 1994

N2 - Lactase-phlorizin hydrolase (LPH) and sucrase-isomaltase (SI) are enterocyte-specific gene products. The identification of regulatory cis-elements in the promoter of these two genes has enabled us to carry out comparative studies of the corresponding intestinal-specific nuclear factors (NF-LPH1 and SIF1-BP). Electrophoretic mobility shift assays demonstrated that the two nuclear factors compete for binding on the same cis-elements. The molecular size of the DNA binding polypeptide is estimated to be approximately 50 kDa for both factors. In the native form the factors are found as 250 kDa oligomeric complexes. Based on these results NF-LPH1 and SIF1-BP are suggested to be either identical or closely related molecules.

AB - Lactase-phlorizin hydrolase (LPH) and sucrase-isomaltase (SI) are enterocyte-specific gene products. The identification of regulatory cis-elements in the promoter of these two genes has enabled us to carry out comparative studies of the corresponding intestinal-specific nuclear factors (NF-LPH1 and SIF1-BP). Electrophoretic mobility shift assays demonstrated that the two nuclear factors compete for binding on the same cis-elements. The molecular size of the DNA binding polypeptide is estimated to be approximately 50 kDa for both factors. In the native form the factors are found as 250 kDa oligomeric complexes. Based on these results NF-LPH1 and SIF1-BP are suggested to be either identical or closely related molecules.

M3 - Journal article

C2 - 8150088

VL - 342

SP - 297

EP - 301

JO - F E B S Letters

JF - F E B S Letters

SN - 0014-5793

IS - 3

ER -

ID: 6586676