Transcatheter Intervention for Coarctation of the Aorta: A Nordic Population-Based Registry With Long-Term Follow-Up
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Background: Coarctation of the aorta (CoA), a congenital narrowing of the proximal descending thoracic aorta, is a relatively common form of congenital heart disease. Untreated significant CoA has a major impact on morbidity and mortality. In the past 3 decades, transcatheter intervention (TCI) for CoA has evolved as an alternative to surgery. Objectives: The authors report on all TCIs for CoA performed from 2000 to 2016 in 4 countries covering 25 million inhabitants, with a mean follow-up duration of 6.9 years. Methods: During the study period, 683 interventions were performed on 542 patients. Results: The procedural success rate was 88%, with 9% considered partly successful. Complications at the intervention site occurred in 3.5% of interventions and at the access site in 3.5%. There was no in-hospital mortality. During follow-up, TCI for CoA reduced the presence of hypertension significantly from 73% to 34%, but despite this, many patients remained hypertensive and in need of continuous antihypertensive treatment. Moreover, 8% to 9% of patients needed aortic and/or aortic valve surgery during follow-up. Conclusions: TCI for CoA can be performed with a low risk for complications. Lifetime follow-up after TCI for CoA seems warranted.
Originalsprog | Engelsk |
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Tidsskrift | JACC: Cardiovascular Interventions |
Vol/bind | 16 |
Udgave nummer | 4 |
Sider (fra-til) | 444-453 |
Antal sider | 10 |
ISSN | 1936-8798 |
DOI | |
Status | Udgivet - 2023 |
Bibliografisk note
Funding Information:
The technical assistance of study coordinators Helena Dellborg and Gorel Hultsberg-Olsson is gratefully acknowledged. The authors thank Hugh McGonigle, of Edanz (https://www.edanz.com/ac), for editing a draft of the manuscript.
Publisher Copyright:
© 2023 American College of Cardiology Foundation
ID: 370202476