TY - JOUR

T1 - Transcatheter Intervention for Coarctation of the Aorta

T2 - A Nordic Population-Based Registry With Long-Term Follow-Up

AU - Eriksson, Peter

AU - Pihkala, Jaana

AU - Jensen, Annette S.

AU - Dohlen, Gaute

AU - Liuba, Petru

AU - Wahlander, Hakan

AU - Sjoberg, Gunnar

AU - Hlebowicz, Joanna

AU - Furenas, Eva

AU - Leirgul, Elisabeth

AU - Settergren, Magnus

AU - Vithessonthi, Kanyalak

AU - Nielsen, Niels Erik

AU - Christersson, Christina

AU - Sondergaard, Lars

AU - Sinisalo, Juha

AU - Nielsen-Kudsk, Jens Erik

AU - Dellborg, Mikael

AU - Larsen, Signe H.

N1 - Publisher Copyright: © 2023 American College of Cardiology Foundation

PY - 2023

Y1 - 2023

N2 - Background: Coarctation of the aorta (CoA), a congenital narrowing of the proximal descending thoracic aorta, is a relatively common form of congenital heart disease. Untreated significant CoA has a major impact on morbidity and mortality. In the past 3 decades, transcatheter intervention (TCI) for CoA has evolved as an alternative to surgery. Objectives: The authors report on all TCIs for CoA performed from 2000 to 2016 in 4 countries covering 25 million inhabitants, with a mean follow-up duration of 6.9 years. Methods: During the study period, 683 interventions were performed on 542 patients. Results: The procedural success rate was 88%, with 9% considered partly successful. Complications at the intervention site occurred in 3.5% of interventions and at the access site in 3.5%. There was no in-hospital mortality. During follow-up, TCI for CoA reduced the presence of hypertension significantly from 73% to 34%, but despite this, many patients remained hypertensive and in need of continuous antihypertensive treatment. Moreover, 8% to 9% of patients needed aortic and/or aortic valve surgery during follow-up. Conclusions: TCI for CoA can be performed with a low risk for complications. Lifetime follow-up after TCI for CoA seems warranted.

AB - Background: Coarctation of the aorta (CoA), a congenital narrowing of the proximal descending thoracic aorta, is a relatively common form of congenital heart disease. Untreated significant CoA has a major impact on morbidity and mortality. In the past 3 decades, transcatheter intervention (TCI) for CoA has evolved as an alternative to surgery. Objectives: The authors report on all TCIs for CoA performed from 2000 to 2016 in 4 countries covering 25 million inhabitants, with a mean follow-up duration of 6.9 years. Methods: During the study period, 683 interventions were performed on 542 patients. Results: The procedural success rate was 88%, with 9% considered partly successful. Complications at the intervention site occurred in 3.5% of interventions and at the access site in 3.5%. There was no in-hospital mortality. During follow-up, TCI for CoA reduced the presence of hypertension significantly from 73% to 34%, but despite this, many patients remained hypertensive and in need of continuous antihypertensive treatment. Moreover, 8% to 9% of patients needed aortic and/or aortic valve surgery during follow-up. Conclusions: TCI for CoA can be performed with a low risk for complications. Lifetime follow-up after TCI for CoA seems warranted.

KW - catheter intervention

KW - coarctation of Aorta

KW - congenital heart disease

UR - http://www.scopus.com/inward/record.url?scp=85148647929&partnerID=8YFLogxK

U2 - 10.1016/j.jcin.2022.11.007

DO - 10.1016/j.jcin.2022.11.007

M3 - Journal article

C2 - 36858664

AN - SCOPUS:85148647929

VL - 16

SP - 444

EP - 453

JO - J A C C: Cardiovascular Interventions

JF - J A C C: Cardiovascular Interventions

SN - 1936-8798

IS - 4

ER -