Thin or early melanoma, risk factors and associated mortality
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Thin or early melanoma, risk factors and associated mortality. / Steding-Jessen, Marianne; Hölmich, Lisbet Rosenkrantz; Chakera, Annette H.; Klausen, Siri; Hovaldt, Hanna Birkbak; Møller, Henrik.
I: Danish Medical Journal, Bind 69, Nr. 9, 01220020, 2022.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Thin or early melanoma, risk factors and associated mortality
AU - Steding-Jessen, Marianne
AU - Hölmich, Lisbet Rosenkrantz
AU - Chakera, Annette H.
AU - Klausen, Siri
AU - Hovaldt, Hanna Birkbak
AU - Møller, Henrik
PY - 2022
Y1 - 2022
N2 - INTRODUCTION. The incidence of thin and early-stage melanoma is increasing in many populations, but the clinical significance of these lesions remains partly unknown. METHODS. Firstly, melanoma deaths in Denmark (2009-2018) were followed back to establish melanoma debut in these persons. Secondly, using national registries of cancer incidence and mortality, 27,036 persons with thin or early-stage melanoma were followed-up for melanoma death. RESULTS. It is estimated that in 11% of the persons who died from melanoma, the debut was a thin or early-stage melanoma. On follow-up of persons with thin or early-stage melanoma, the 20-year risk of dying from melanoma was 3%. CONCLUSION. The absolute risk of melanoma death after a diagnosis with thin or early-stage melanoma is low. A subgroup of patients who are at a high risk may possibly be identified by a combination of stage, thickness, ulceration and dermal mitoses.
AB - INTRODUCTION. The incidence of thin and early-stage melanoma is increasing in many populations, but the clinical significance of these lesions remains partly unknown. METHODS. Firstly, melanoma deaths in Denmark (2009-2018) were followed back to establish melanoma debut in these persons. Secondly, using national registries of cancer incidence and mortality, 27,036 persons with thin or early-stage melanoma were followed-up for melanoma death. RESULTS. It is estimated that in 11% of the persons who died from melanoma, the debut was a thin or early-stage melanoma. On follow-up of persons with thin or early-stage melanoma, the 20-year risk of dying from melanoma was 3%. CONCLUSION. The absolute risk of melanoma death after a diagnosis with thin or early-stage melanoma is low. A subgroup of patients who are at a high risk may possibly be identified by a combination of stage, thickness, ulceration and dermal mitoses.
KW - SEVERE HYPOGLYCEMIA
KW - IMPAIRED AWARENESS
KW - INVASIVE MELANOMA
KW - INSULIN ANALOGS
KW - IN-SITU
KW - TYPE-1
KW - QUEENSLAND
KW - FREQUENCY
KW - SURVIVAL
KW - RATES
M3 - Journal article
VL - 69
JO - Danish Medical Journal
JF - Danish Medical Journal
SN - 2245-1919
IS - 9
M1 - 01220020
ER -
ID: 325706993