The utility of pharmacogenetics testing in psychiatric populations
Publikation: Bidrag til tidsskrift › Leder › Forskning › fagfællebedømt
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The utility of pharmacogenetics testing in psychiatric populations. / Jürgens, Gesche.
I: Journal of Personalized Medicine, Bind 11, Nr. 12, 1262, 2021.Publikation: Bidrag til tidsskrift › Leder › Forskning › fagfællebedømt
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TY - JOUR
T1 - The utility of pharmacogenetics testing in psychiatric populations
AU - Jürgens, Gesche
N1 - Publisher Copyright: © 2021 by the author. Licensee MDPI, Basel, Switzerland.
PY - 2021
Y1 - 2021
N2 - The implementation of pharmacogenetic tests including multiple gene variants has shown promising potential as a decision-making tool for optimizing psychopharmacological treatment regimens and reducing treatment costs. However, the varying clinical validity of gene variants included in pharmacogenetic test batteries, and inconsistencies in their translation into medical recommendations between commercially available pharmacogenetic tests, complicates their rational implementation. Thus, there is a need for well-designed, reproducible studies documenting the clinical significance of the various genetic variants.
AB - The implementation of pharmacogenetic tests including multiple gene variants has shown promising potential as a decision-making tool for optimizing psychopharmacological treatment regimens and reducing treatment costs. However, the varying clinical validity of gene variants included in pharmacogenetic test batteries, and inconsistencies in their translation into medical recommendations between commercially available pharmacogenetic tests, complicates their rational implementation. Thus, there is a need for well-designed, reproducible studies documenting the clinical significance of the various genetic variants.
KW - Pharmacogenetic testing
KW - Pharmacotherapy
KW - Psychiatric disorders
U2 - 10.3390/jpm11121262
DO - 10.3390/jpm11121262
M3 - Editorial
C2 - 34945734
AN - SCOPUS:85120805596
VL - 11
JO - Journal of Personalized Medicine
JF - Journal of Personalized Medicine
SN - 2075-4426
IS - 12
M1 - 1262
ER -
ID: 305555592