The undesirable effects of neuromuscular blocking drugs

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Standard

The undesirable effects of neuromuscular blocking drugs. / Claudius, C; Garvey, L H; Viby-Mogensen, J.

I: Anaesthesia, Bind 64 Suppl 1, 2009, s. 10-21.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Claudius, C, Garvey, LH & Viby-Mogensen, J 2009, 'The undesirable effects of neuromuscular blocking drugs', Anaesthesia, bind 64 Suppl 1, s. 10-21. https://doi.org/10.1111/j.1365-2044.2008.05866.x

APA

Claudius, C., Garvey, L. H., & Viby-Mogensen, J. (2009). The undesirable effects of neuromuscular blocking drugs. Anaesthesia, 64 Suppl 1, 10-21. https://doi.org/10.1111/j.1365-2044.2008.05866.x

Vancouver

Claudius C, Garvey LH, Viby-Mogensen J. The undesirable effects of neuromuscular blocking drugs. Anaesthesia. 2009;64 Suppl 1:10-21. https://doi.org/10.1111/j.1365-2044.2008.05866.x

Author

Claudius, C ; Garvey, L H ; Viby-Mogensen, J. / The undesirable effects of neuromuscular blocking drugs. I: Anaesthesia. 2009 ; Bind 64 Suppl 1. s. 10-21.

Bibtex

@article{b429049067db11df928f000ea68e967b,
title = "The undesirable effects of neuromuscular blocking drugs",
abstract = "Neuromuscular blocking drugs are designed to bind to the nicotinic receptor at the neuromuscular junction. However, they also interact with other acetylcholine receptors in the body. Binding to these receptors causes adverse effects that vary with the specificity for the cholinergic receptor in question. Moreover, all neuromuscular blocking drugs may cause hypersensitivity reactions. Often the symptoms are mild and self-limiting but massive histamine release can cause systematic reactions with circulatory and respiratory symptoms and signs. At the end of anaesthesia, no residual effect of a neuromuscular blocking drug should be present. However, the huge variability in response to neuromuscular blocking drugs makes it impossible to predict which patient will suffer postoperative residual curarization. This article discusses the undesirable effects of the currently available neuromuscular blocking drugs including the definitions, diagnosis and causes of hypersensitivity reactions and postoperative residual curarisation.",
author = "C Claudius and Garvey, {L H} and J Viby-Mogensen",
note = "Keywords: Anesthesia Recovery Period; Drug Hypersensitivity; Humans; Neuromuscular Blockade; Neuromuscular Blocking Agents; Neuromuscular Junction",
year = "2009",
doi = "10.1111/j.1365-2044.2008.05866.x",
language = "English",
volume = "64 Suppl 1",
pages = "10--21",
journal = "Anaesthesia",
issn = "0003-2409",
publisher = "Wiley-Blackwell",

}

RIS

TY - JOUR

T1 - The undesirable effects of neuromuscular blocking drugs

AU - Claudius, C

AU - Garvey, L H

AU - Viby-Mogensen, J

N1 - Keywords: Anesthesia Recovery Period; Drug Hypersensitivity; Humans; Neuromuscular Blockade; Neuromuscular Blocking Agents; Neuromuscular Junction

PY - 2009

Y1 - 2009

N2 - Neuromuscular blocking drugs are designed to bind to the nicotinic receptor at the neuromuscular junction. However, they also interact with other acetylcholine receptors in the body. Binding to these receptors causes adverse effects that vary with the specificity for the cholinergic receptor in question. Moreover, all neuromuscular blocking drugs may cause hypersensitivity reactions. Often the symptoms are mild and self-limiting but massive histamine release can cause systematic reactions with circulatory and respiratory symptoms and signs. At the end of anaesthesia, no residual effect of a neuromuscular blocking drug should be present. However, the huge variability in response to neuromuscular blocking drugs makes it impossible to predict which patient will suffer postoperative residual curarization. This article discusses the undesirable effects of the currently available neuromuscular blocking drugs including the definitions, diagnosis and causes of hypersensitivity reactions and postoperative residual curarisation.

AB - Neuromuscular blocking drugs are designed to bind to the nicotinic receptor at the neuromuscular junction. However, they also interact with other acetylcholine receptors in the body. Binding to these receptors causes adverse effects that vary with the specificity for the cholinergic receptor in question. Moreover, all neuromuscular blocking drugs may cause hypersensitivity reactions. Often the symptoms are mild and self-limiting but massive histamine release can cause systematic reactions with circulatory and respiratory symptoms and signs. At the end of anaesthesia, no residual effect of a neuromuscular blocking drug should be present. However, the huge variability in response to neuromuscular blocking drugs makes it impossible to predict which patient will suffer postoperative residual curarization. This article discusses the undesirable effects of the currently available neuromuscular blocking drugs including the definitions, diagnosis and causes of hypersensitivity reactions and postoperative residual curarisation.

U2 - 10.1111/j.1365-2044.2008.05866.x

DO - 10.1111/j.1365-2044.2008.05866.x

M3 - Journal article

C2 - 19222427

VL - 64 Suppl 1

SP - 10

EP - 21

JO - Anaesthesia

JF - Anaesthesia

SN - 0003-2409

ER -

ID: 19952241