The relationship of alcohol consumption to total immunoglobulin E and the development of immunoglobulin E sensitization: the Copenhagen Allergy Study

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Standard

The relationship of alcohol consumption to total immunoglobulin E and the development of immunoglobulin E sensitization : the Copenhagen Allergy Study. / Linneberg, A; Petersen, J; Nielsen, N H; Madsen, F; Frølund, L; Dirksen, A; Jørgensen, T.

I: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, Bind 33, Nr. 2, 02.2003, s. 192-8.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Linneberg, A, Petersen, J, Nielsen, NH, Madsen, F, Frølund, L, Dirksen, A & Jørgensen, T 2003, 'The relationship of alcohol consumption to total immunoglobulin E and the development of immunoglobulin E sensitization: the Copenhagen Allergy Study', Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, bind 33, nr. 2, s. 192-8.

APA

Linneberg, A., Petersen, J., Nielsen, N. H., Madsen, F., Frølund, L., Dirksen, A., & Jørgensen, T. (2003). The relationship of alcohol consumption to total immunoglobulin E and the development of immunoglobulin E sensitization: the Copenhagen Allergy Study. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 33(2), 192-8.

Vancouver

Linneberg A, Petersen J, Nielsen NH, Madsen F, Frølund L, Dirksen A o.a. The relationship of alcohol consumption to total immunoglobulin E and the development of immunoglobulin E sensitization: the Copenhagen Allergy Study. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. 2003 feb.;33(2):192-8.

Author

Linneberg, A ; Petersen, J ; Nielsen, N H ; Madsen, F ; Frølund, L ; Dirksen, A ; Jørgensen, T. / The relationship of alcohol consumption to total immunoglobulin E and the development of immunoglobulin E sensitization : the Copenhagen Allergy Study. I: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. 2003 ; Bind 33, Nr. 2. s. 192-8.

Bibtex

@article{a671f1ef4935409daa9e27738f75c461,
title = "The relationship of alcohol consumption to total immunoglobulin E and the development of immunoglobulin E sensitization: the Copenhagen Allergy Study",
abstract = "BACKGROUND: Several studies in patient populations have reported a positive association between alcohol consumption and serum total IgE. Furthermore, we have previously reported a positive association between alcohol consumption and the prevalence of skin prick test (SPT positivity) to inhalant allergens in a population-based cross-sectional study.OBJECTIVE: To investigate the relationship of alcohol consumption to levels of serum total IgE and the development of IgE sensitization to inhalant allergens.METHODS: In 1990, self-reported consumption of alcohol, serum total IgE, SPT positivity and specific IgE positivity to inhalant allergens were assessed in 1112 subjects, aged 15-69 years, participating in a population-based cross-sectional study in Copenhagen, Denmark. In 1998, they were invited to a follow-up and 734 were re-examined (participation rate 69.0%). Adjustment for potential confounders was performed by using multivariable regression analyses.RESULTS: In non-atopic (specific IgE negative) subjects there was a positive association between alcohol consumption and the concentration of total IgE (P = 0.001). During the follow-up period, 45 and 33 subjects developed SPT positivity and specific IgE positivity, respectively. There was no significant association between alcohol consumption and the development of SPT positivity or specific IgE positivity. However, the risk of developing SPT positivity tended to increase with increasing consumption of alcohol (P = 0.055).CONCLUSIONS: This epidemiological study confirms that alcohol consumption has an influence on levels of serum total IgE. A significant association between alcohol consumption and the development of IgE sensitization was not established. However, there seems to be a lack epidemiological data on this issue.",
keywords = "Adolescent, Adult, Aged, Alcohol Drinking, Allergens, Ethanol, Follow-Up Studies, Humans, Hypersensitivity, Immediate, Immunoglobulin E, Linear Models, Middle Aged, Odds Ratio, Skin Tests, Journal Article, Research Support, Non-U.S. Gov't",
author = "A Linneberg and J Petersen and Nielsen, {N H} and F Madsen and L Fr{\o}lund and A Dirksen and T J{\o}rgensen",
year = "2003",
month = feb,
language = "English",
volume = "33",
pages = "192--8",
journal = "Clinical Allergy",
issn = "0954-7894",
publisher = "Wiley-Blackwell",
number = "2",

}

RIS

TY - JOUR

T1 - The relationship of alcohol consumption to total immunoglobulin E and the development of immunoglobulin E sensitization

T2 - the Copenhagen Allergy Study

AU - Linneberg, A

AU - Petersen, J

AU - Nielsen, N H

AU - Madsen, F

AU - Frølund, L

AU - Dirksen, A

AU - Jørgensen, T

PY - 2003/2

Y1 - 2003/2

N2 - BACKGROUND: Several studies in patient populations have reported a positive association between alcohol consumption and serum total IgE. Furthermore, we have previously reported a positive association between alcohol consumption and the prevalence of skin prick test (SPT positivity) to inhalant allergens in a population-based cross-sectional study.OBJECTIVE: To investigate the relationship of alcohol consumption to levels of serum total IgE and the development of IgE sensitization to inhalant allergens.METHODS: In 1990, self-reported consumption of alcohol, serum total IgE, SPT positivity and specific IgE positivity to inhalant allergens were assessed in 1112 subjects, aged 15-69 years, participating in a population-based cross-sectional study in Copenhagen, Denmark. In 1998, they were invited to a follow-up and 734 were re-examined (participation rate 69.0%). Adjustment for potential confounders was performed by using multivariable regression analyses.RESULTS: In non-atopic (specific IgE negative) subjects there was a positive association between alcohol consumption and the concentration of total IgE (P = 0.001). During the follow-up period, 45 and 33 subjects developed SPT positivity and specific IgE positivity, respectively. There was no significant association between alcohol consumption and the development of SPT positivity or specific IgE positivity. However, the risk of developing SPT positivity tended to increase with increasing consumption of alcohol (P = 0.055).CONCLUSIONS: This epidemiological study confirms that alcohol consumption has an influence on levels of serum total IgE. A significant association between alcohol consumption and the development of IgE sensitization was not established. However, there seems to be a lack epidemiological data on this issue.

AB - BACKGROUND: Several studies in patient populations have reported a positive association between alcohol consumption and serum total IgE. Furthermore, we have previously reported a positive association between alcohol consumption and the prevalence of skin prick test (SPT positivity) to inhalant allergens in a population-based cross-sectional study.OBJECTIVE: To investigate the relationship of alcohol consumption to levels of serum total IgE and the development of IgE sensitization to inhalant allergens.METHODS: In 1990, self-reported consumption of alcohol, serum total IgE, SPT positivity and specific IgE positivity to inhalant allergens were assessed in 1112 subjects, aged 15-69 years, participating in a population-based cross-sectional study in Copenhagen, Denmark. In 1998, they were invited to a follow-up and 734 were re-examined (participation rate 69.0%). Adjustment for potential confounders was performed by using multivariable regression analyses.RESULTS: In non-atopic (specific IgE negative) subjects there was a positive association between alcohol consumption and the concentration of total IgE (P = 0.001). During the follow-up period, 45 and 33 subjects developed SPT positivity and specific IgE positivity, respectively. There was no significant association between alcohol consumption and the development of SPT positivity or specific IgE positivity. However, the risk of developing SPT positivity tended to increase with increasing consumption of alcohol (P = 0.055).CONCLUSIONS: This epidemiological study confirms that alcohol consumption has an influence on levels of serum total IgE. A significant association between alcohol consumption and the development of IgE sensitization was not established. However, there seems to be a lack epidemiological data on this issue.

KW - Adolescent

KW - Adult

KW - Aged

KW - Alcohol Drinking

KW - Allergens

KW - Ethanol

KW - Follow-Up Studies

KW - Humans

KW - Hypersensitivity, Immediate

KW - Immunoglobulin E

KW - Linear Models

KW - Middle Aged

KW - Odds Ratio

KW - Skin Tests

KW - Journal Article

KW - Research Support, Non-U.S. Gov't

M3 - Journal article

C2 - 12580911

VL - 33

SP - 192

EP - 198

JO - Clinical Allergy

JF - Clinical Allergy

SN - 0954-7894

IS - 2

ER -

ID: 173163647