TY - JOUR

T1 - The Lancet Commission to reduce the global burden of sudden cardiac death

T2 - a call for multidisciplinary action

AU - Marijon, Eloi

AU - Narayanan, Kumar

AU - Smith, Karen

AU - Barra, Sérgio

AU - Basso, Cristina

AU - Blom, Marieke T.

AU - Crotti, Lia

AU - D'Avila, Andre

AU - Deo, Rajat

AU - Dumas, Florence

AU - Dzudie, Anastase

AU - Farrugia, Audrey

AU - Greeley, Kaitlyn

AU - Hindricks, Gerhard

AU - Hua, Wei

AU - Ingles, Jodie

AU - Iwami, Taku

AU - Junttila, Juhani

AU - Koster, Rudolph W.

AU - De Waroux, Jean Benoît Le Polain

AU - Olasveengen, Theresa M.

AU - Ong, Marcus E. H.

AU - Papadakis, Michael

AU - Sasson, Comilla

AU - Shin, Sang Do

AU - Tse, Hung-Fat

AU - Tseng, Zian

AU - Van Der Werf, Christian

AU - Folke, Fredrik

AU - Albert, Christine M.

AU - Winkel, Bo Gregers

N1 - Publisher Copyright: © 2023 Elsevier Ltd

PY - 2023

Y1 - 2023

N2 - Despite major advancements in cardiovascular medicine, sudden cardiac death (SCD) continues to be an enormous medical and societal challenge, claiming millions of lives every year. Efforts to prevent SCD are hampered by imperfect risk prediction and inadequate solutions to specifically address arrhythmogenesis. Although resuscitation strategies have witnessed substantial evolution, there is a need to strengthen the organisation of community interventions and emergency medical systems across varied locations and health-care structures. With all the technological and medical advances of the 21st century, the fact that survival from sudden cardiac arrest (SCA) remains lower than 10% in most parts of the world is unacceptable. Recognising this urgent need, the Lancet Commission on SCD was constituted, bringing together 30 international experts in varied disciplines. Consistent progress in tackling SCD will require a completely revamped approach to SCD prevention, with wide-sweeping policy changes that will empower the development of both governmental and community-based programmes to maximise survival from SCA, and to comprehensively attend to survivors and decedents’ families after the event. International collaborative efforts that maximally leverage and connect the expertise of various research organisations will need to be prioritised to properly address identified gaps. The Commission places substantial emphasis on the need to develop a multidisciplinary strategy that encompasses all aspects of SCD prevention and treatment. The Commission provides a critical assessment of the current scientific efforts in the field, and puts forth key recommendations to challenge, activate, and intensify efforts by both the scientific and global community with new directions, research, and innovation to reduce the burden of SCD worldwide.

AB - Despite major advancements in cardiovascular medicine, sudden cardiac death (SCD) continues to be an enormous medical and societal challenge, claiming millions of lives every year. Efforts to prevent SCD are hampered by imperfect risk prediction and inadequate solutions to specifically address arrhythmogenesis. Although resuscitation strategies have witnessed substantial evolution, there is a need to strengthen the organisation of community interventions and emergency medical systems across varied locations and health-care structures. With all the technological and medical advances of the 21st century, the fact that survival from sudden cardiac arrest (SCA) remains lower than 10% in most parts of the world is unacceptable. Recognising this urgent need, the Lancet Commission on SCD was constituted, bringing together 30 international experts in varied disciplines. Consistent progress in tackling SCD will require a completely revamped approach to SCD prevention, with wide-sweeping policy changes that will empower the development of both governmental and community-based programmes to maximise survival from SCA, and to comprehensively attend to survivors and decedents’ families after the event. International collaborative efforts that maximally leverage and connect the expertise of various research organisations will need to be prioritised to properly address identified gaps. The Commission places substantial emphasis on the need to develop a multidisciplinary strategy that encompasses all aspects of SCD prevention and treatment. The Commission provides a critical assessment of the current scientific efforts in the field, and puts forth key recommendations to challenge, activate, and intensify efforts by both the scientific and global community with new directions, research, and innovation to reduce the burden of SCD worldwide.

U2 - 10.1016/S0140-6736(23)00875-9

DO - 10.1016/S0140-6736(23)00875-9

M3 - Review

C2 - 37647926

AN - SCOPUS:85170438951

VL - 402

SP - 883

EP - 936

JO - The Lancet

JF - The Lancet

SN - 0140-6736

IS - 10405

ER -