The impact of dysfunctional breathing on the level of asthma control in difficult asthma

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The impact of dysfunctional breathing on the level of asthma control in difficult asthma. / Sedeh, Farnam Barati; Von Bülow, Anna; Backer, Vibeke; Bodtger, Uffe; Petersen, Ulrik Søes; Vest, Susanne; Hull, James H; Porsbjerg, Celeste.

I: Respiratory Medicine, Bind 163, 105894, 2020.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Sedeh, FB, Von Bülow, A, Backer, V, Bodtger, U, Petersen, US, Vest, S, Hull, JH & Porsbjerg, C 2020, 'The impact of dysfunctional breathing on the level of asthma control in difficult asthma', Respiratory Medicine, bind 163, 105894. https://doi.org/10.1016/j.rmed.2020.105894

APA

Sedeh, F. B., Von Bülow, A., Backer, V., Bodtger, U., Petersen, U. S., Vest, S., Hull, J. H., & Porsbjerg, C. (2020). The impact of dysfunctional breathing on the level of asthma control in difficult asthma. Respiratory Medicine, 163, [105894]. https://doi.org/10.1016/j.rmed.2020.105894

Vancouver

Sedeh FB, Von Bülow A, Backer V, Bodtger U, Petersen US, Vest S o.a. The impact of dysfunctional breathing on the level of asthma control in difficult asthma. Respiratory Medicine. 2020;163. 105894. https://doi.org/10.1016/j.rmed.2020.105894

Author

Sedeh, Farnam Barati ; Von Bülow, Anna ; Backer, Vibeke ; Bodtger, Uffe ; Petersen, Ulrik Søes ; Vest, Susanne ; Hull, James H ; Porsbjerg, Celeste. / The impact of dysfunctional breathing on the level of asthma control in difficult asthma. I: Respiratory Medicine. 2020 ; Bind 163.

Bibtex

@article{f8631f8654ed4bc9871783a422c214a9,

title = "The impact of dysfunctional breathing on the level of asthma control in difficult asthma",

abstract = "BACKGROUND: Difficult asthma is defined as asthma requiring high dose treatment. However, systematic assessment is required to differentiate severe asthma from difficult-to-treat asthma. Dysfunctional breathing (DB) is a common comorbidity in difficult asthma, which may contribute to symptoms, but how it affects commonly used measures of symptom control is unclear.METHODS: All adult asthma patients seen in four respiratory clinics over one year were screened prospectively, and patients with possible severe asthma according to ERS/ATS criteria ('Difficult asthma': high-dose inhaled corticosteroids/oral corticosteroids), underwent systematic assessment. Symptoms of DB were assessed utilizing a symptom based subjective tool, Nijmegen questionnaire (NQ), and objective signs of DB with the Breathing Pattern Assessment Tool (BPAT). Asthma control and quality of life were evaluated with the Asthma Control Questionnaire (ACQ) and the mini Asthma Quality of Life Questionnaire (AQLQ).RESULTS: A total of 117 patients were included. Among these, 29.9% (35/117) had DB according to the NQ. Patients with DB had a poorer asthma control (ACQ: Mean (SD) 2.86 ± 1.05 vs. 1.46 ± 0.93) and lower quality of life (AQLQ score: Mean (SD) 4.2 ± 1.04 vs. 5.49 ± 0.85) compared to patients without DB. Similarly, patients with objective signs of DB according to the BPAT score had worse asthma control: BPAT >4 vs < 4: (ACQ: Mean (SD) 3.15 ± 0.93 vs 2.03 ± 1.15).CONCLUSION: DB is common among patients with difficult asthma, and is associated with significantly poorer asthma control and lower quality of life. Assessment and treatment of DB is an important part of the management of difficult asthma.",

keywords = "Administration, Inhalation, Administration, Oral, Adrenal Cortex Hormones/administration & dosage, Adult, Aged, Aged, 80 and over, Asthma/diagnosis, Cross-Sectional Studies, Female, Humans, Male, Middle Aged, Prospective Studies, Quality of Life, Respiration, Severity of Illness Index, Young Adult",

author = "Sedeh, {Farnam Barati} and {Von B{\"u}low}, Anna and Vibeke Backer and Uffe Bodtger and Petersen, {Ulrik S{\o}es} and Susanne Vest and Hull, {James H} and Celeste Porsbjerg",

year = "2020",

doi = "10.1016/j.rmed.2020.105894",

language = "English",

volume = "163",

journal = "Respiratory Medicine",

issn = "0954-6111",

publisher = "Elsevier",

}

RIS

TY - JOUR

T1 - The impact of dysfunctional breathing on the level of asthma control in difficult asthma

AU - Sedeh, Farnam Barati

AU - Von Bülow, Anna

AU - Backer, Vibeke

AU - Bodtger, Uffe

AU - Petersen, Ulrik Søes

AU - Vest, Susanne

AU - Hull, James H

AU - Porsbjerg, Celeste

PY - 2020

Y1 - 2020

N2 - BACKGROUND: Difficult asthma is defined as asthma requiring high dose treatment. However, systematic assessment is required to differentiate severe asthma from difficult-to-treat asthma. Dysfunctional breathing (DB) is a common comorbidity in difficult asthma, which may contribute to symptoms, but how it affects commonly used measures of symptom control is unclear.METHODS: All adult asthma patients seen in four respiratory clinics over one year were screened prospectively, and patients with possible severe asthma according to ERS/ATS criteria ('Difficult asthma': high-dose inhaled corticosteroids/oral corticosteroids), underwent systematic assessment. Symptoms of DB were assessed utilizing a symptom based subjective tool, Nijmegen questionnaire (NQ), and objective signs of DB with the Breathing Pattern Assessment Tool (BPAT). Asthma control and quality of life were evaluated with the Asthma Control Questionnaire (ACQ) and the mini Asthma Quality of Life Questionnaire (AQLQ).RESULTS: A total of 117 patients were included. Among these, 29.9% (35/117) had DB according to the NQ. Patients with DB had a poorer asthma control (ACQ: Mean (SD) 2.86 ± 1.05 vs. 1.46 ± 0.93) and lower quality of life (AQLQ score: Mean (SD) 4.2 ± 1.04 vs. 5.49 ± 0.85) compared to patients without DB. Similarly, patients with objective signs of DB according to the BPAT score had worse asthma control: BPAT >4 vs < 4: (ACQ: Mean (SD) 3.15 ± 0.93 vs 2.03 ± 1.15).CONCLUSION: DB is common among patients with difficult asthma, and is associated with significantly poorer asthma control and lower quality of life. Assessment and treatment of DB is an important part of the management of difficult asthma.

AB - BACKGROUND: Difficult asthma is defined as asthma requiring high dose treatment. However, systematic assessment is required to differentiate severe asthma from difficult-to-treat asthma. Dysfunctional breathing (DB) is a common comorbidity in difficult asthma, which may contribute to symptoms, but how it affects commonly used measures of symptom control is unclear.METHODS: All adult asthma patients seen in four respiratory clinics over one year were screened prospectively, and patients with possible severe asthma according to ERS/ATS criteria ('Difficult asthma': high-dose inhaled corticosteroids/oral corticosteroids), underwent systematic assessment. Symptoms of DB were assessed utilizing a symptom based subjective tool, Nijmegen questionnaire (NQ), and objective signs of DB with the Breathing Pattern Assessment Tool (BPAT). Asthma control and quality of life were evaluated with the Asthma Control Questionnaire (ACQ) and the mini Asthma Quality of Life Questionnaire (AQLQ).RESULTS: A total of 117 patients were included. Among these, 29.9% (35/117) had DB according to the NQ. Patients with DB had a poorer asthma control (ACQ: Mean (SD) 2.86 ± 1.05 vs. 1.46 ± 0.93) and lower quality of life (AQLQ score: Mean (SD) 4.2 ± 1.04 vs. 5.49 ± 0.85) compared to patients without DB. Similarly, patients with objective signs of DB according to the BPAT score had worse asthma control: BPAT >4 vs < 4: (ACQ: Mean (SD) 3.15 ± 0.93 vs 2.03 ± 1.15).CONCLUSION: DB is common among patients with difficult asthma, and is associated with significantly poorer asthma control and lower quality of life. Assessment and treatment of DB is an important part of the management of difficult asthma.

KW - Administration, Inhalation

KW - Administration, Oral

KW - Adrenal Cortex Hormones/administration & dosage

KW - Adult

KW - Aged

KW - Aged, 80 and over

KW - Asthma/diagnosis

KW - Cross-Sectional Studies

KW - Female

KW - Humans

KW - Male

KW - Middle Aged

KW - Prospective Studies

KW - Quality of Life

KW - Respiration

KW - Severity of Illness Index

KW - Young Adult

U2 - 10.1016/j.rmed.2020.105894

DO - 10.1016/j.rmed.2020.105894

M3 - Journal article

C2 - 32056838

VL - 163

JO - Respiratory Medicine

JF - Respiratory Medicine

SN - 0954-6111

M1 - 105894

ER -

ID: 257029163