The epidermal growth factor precursor in the rat kidney seems to be processed by an aprotinin sensitive proteinase
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Epidermal growth factor (EGF) is synthesized as a membrane bound precursor in the rat kidney. The precursor seems to be processed by an aprotinin sensitive proteinase. Intravenous infusion of aprotinin reduces the urinary excretion of EGF by 85% and increases the amount of renal EGF. Kidney membranes incubated at 37 degrees C release EGF and this release is inhibited by aprotinin.
Originalsprog | Engelsk |
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Tidsskrift | Agents and actions. Supplements |
Vol/bind | 38 ( Pt 2) |
Sider (fra-til) | 183-90 |
Antal sider | 8 |
ISSN | 0379-0363 |
Status | Udgivet - 1992 |
ID: 47487685