The Association between Genetic Variations of CHI3L1, Levels of the Encoded Glycoprotein YKL-40 and the Lipid Profile in a Danish Population

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The Association between Genetic Variations of CHI3L1, Levels of the Encoded Glycoprotein YKL-40 and the Lipid Profile in a Danish Population. / Thomsen, Stine Brinkløv; Rathcke, Camilla Noelle; Skaaby, Tea; Linneberg, Allan; Vestergaard, Henrik.

I: P L o S One, Bind 7, Nr. 10, 2012, s. e47094.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Thomsen, SB, Rathcke, CN, Skaaby, T, Linneberg, A & Vestergaard, H 2012, 'The Association between Genetic Variations of CHI3L1, Levels of the Encoded Glycoprotein YKL-40 and the Lipid Profile in a Danish Population', P L o S One, bind 7, nr. 10, s. e47094. https://doi.org/10.1371/journal.pone.0047094

APA

Thomsen, S. B., Rathcke, C. N., Skaaby, T., Linneberg, A., & Vestergaard, H. (2012). The Association between Genetic Variations of CHI3L1, Levels of the Encoded Glycoprotein YKL-40 and the Lipid Profile in a Danish Population. P L o S One, 7(10), e47094. https://doi.org/10.1371/journal.pone.0047094

Vancouver

Thomsen SB, Rathcke CN, Skaaby T, Linneberg A, Vestergaard H. The Association between Genetic Variations of CHI3L1, Levels of the Encoded Glycoprotein YKL-40 and the Lipid Profile in a Danish Population. P L o S One. 2012;7(10):e47094. https://doi.org/10.1371/journal.pone.0047094

Author

Thomsen, Stine Brinkløv ; Rathcke, Camilla Noelle ; Skaaby, Tea ; Linneberg, Allan ; Vestergaard, Henrik. / The Association between Genetic Variations of CHI3L1, Levels of the Encoded Glycoprotein YKL-40 and the Lipid Profile in a Danish Population. I: P L o S One. 2012 ; Bind 7, Nr. 10. s. e47094.

Bibtex

@article{b904a36c1a2e44f2aece40e168a1fdce,

title = "The Association between Genetic Variations of CHI3L1, Levels of the Encoded Glycoprotein YKL-40 and the Lipid Profile in a Danish Population",

abstract = "The inflammatory biomarker YKL-40 seems to play a role in atherosclerosis and is elevated in patients with obesity, cardiovascular disease and type 2 diabetes. Single nucleotide polymorphisms (SNPs) of the YKL-40 encoding gene, CHI3L1, are associated with inter-individual YKL-40 levels. One study has described an association between a promoter polymorphism of CHI3L1 and levels of low density lipoprotein. The objective of this study was to evaluate the influence of YKL-40 on lipid parameters by determining the association between polymorphisms of CHI3L1, serum YKL-40 and levels of the differentiated lipid profile in a Danish general population.",

author = "Thomsen, {Stine Brinkl{\o}v} and Rathcke, {Camilla Noelle} and Tea Skaaby and Allan Linneberg and Henrik Vestergaard",

year = "2012",

doi = "10.1371/journal.pone.0047094",

language = "English",

volume = "7",

pages = "e47094",

journal = "PLoS ONE",

issn = "1932-6203",

publisher = "Public Library of Science",

number = "10",

}

RIS

TY - JOUR

T1 - The Association between Genetic Variations of CHI3L1, Levels of the Encoded Glycoprotein YKL-40 and the Lipid Profile in a Danish Population

AU - Thomsen, Stine Brinkløv

AU - Rathcke, Camilla Noelle

AU - Skaaby, Tea

AU - Linneberg, Allan

AU - Vestergaard, Henrik

PY - 2012

Y1 - 2012

N2 - The inflammatory biomarker YKL-40 seems to play a role in atherosclerosis and is elevated in patients with obesity, cardiovascular disease and type 2 diabetes. Single nucleotide polymorphisms (SNPs) of the YKL-40 encoding gene, CHI3L1, are associated with inter-individual YKL-40 levels. One study has described an association between a promoter polymorphism of CHI3L1 and levels of low density lipoprotein. The objective of this study was to evaluate the influence of YKL-40 on lipid parameters by determining the association between polymorphisms of CHI3L1, serum YKL-40 and levels of the differentiated lipid profile in a Danish general population.

AB - The inflammatory biomarker YKL-40 seems to play a role in atherosclerosis and is elevated in patients with obesity, cardiovascular disease and type 2 diabetes. Single nucleotide polymorphisms (SNPs) of the YKL-40 encoding gene, CHI3L1, are associated with inter-individual YKL-40 levels. One study has described an association between a promoter polymorphism of CHI3L1 and levels of low density lipoprotein. The objective of this study was to evaluate the influence of YKL-40 on lipid parameters by determining the association between polymorphisms of CHI3L1, serum YKL-40 and levels of the differentiated lipid profile in a Danish general population.

U2 - 10.1371/journal.pone.0047094

DO - 10.1371/journal.pone.0047094

M3 - Journal article

C2 - 23071724

VL - 7

SP - e47094

JO - PLoS ONE

JF - PLoS ONE

SN - 1932-6203

IS - 10

ER -

ID: 48513255