Terapeutisk stofmåling af β-laktamantibiotika
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Standard
Terapeutisk stofmåling af β-laktamantibiotika. / Tanha, Nima; Bathum, Lise; Munk, Jens Kristian; Frimodt-Møller, Niels; Andersen, Christian Østergaard; Benfield, Thomas.
I: Ugeskrift for Laeger, Bind 182, Nr. 39, V01200066, 2020.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Harvard
APA
Vancouver
Author
Bibtex
}
RIS
TY - JOUR
T1 - Terapeutisk stofmåling af β-laktamantibiotika
AU - Tanha, Nima
AU - Bathum, Lise
AU - Munk, Jens Kristian
AU - Frimodt-Møller, Niels
AU - Andersen, Christian Østergaard
AU - Benfield, Thomas
PY - 2020
Y1 - 2020
N2 - Traditional β-lactam antibiotic dosing does not consider physiological changes in medical conditions such as sepsis. Optimal antibiotic exposure could be achieved by therapeutic drug monitoring (TDM). This review gives a brief summary. Current studies are sparse, but suggestive of a potential beneficial role of TDM to patients with reduced renal function, obese patients and the critically ill. TDM can potentially reduce adverse effects and optimise antibiotic exposure. However, standardised TDM methods are lacking and randomised clinical studies are warranted in order to prove clinical benefit.
AB - Traditional β-lactam antibiotic dosing does not consider physiological changes in medical conditions such as sepsis. Optimal antibiotic exposure could be achieved by therapeutic drug monitoring (TDM). This review gives a brief summary. Current studies are sparse, but suggestive of a potential beneficial role of TDM to patients with reduced renal function, obese patients and the critically ill. TDM can potentially reduce adverse effects and optimise antibiotic exposure. However, standardised TDM methods are lacking and randomised clinical studies are warranted in order to prove clinical benefit.
M3 - Tidsskriftartikel
C2 - 33000734
VL - 182
JO - Ugeskrift for Laeger
JF - Ugeskrift for Laeger
SN - 0041-5782
IS - 39
M1 - V01200066
ER -
ID: 269795230