Systemisk toksicitet ved lokalanalgetika
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Systemisk toksicitet ved lokalanalgetika. / Johansson, Karl Sebastian; Høgberg, Lotte Christine Groth; Christensen, Mikkel Bring; Petersen, Tonny Studsgaard; Dalhoff, Kim; Bøgevig, Søren.
I: Ugeskrift for Laeger, Bind 182, Nr. 51, V11190656, 2020.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Systemisk toksicitet ved lokalanalgetika
AU - Johansson, Karl Sebastian
AU - Høgberg, Lotte Christine Groth
AU - Christensen, Mikkel Bring
AU - Petersen, Tonny Studsgaard
AU - Dalhoff, Kim
AU - Bøgevig, Søren
PY - 2020
Y1 - 2020
N2 - Local anaesthetic systemic toxicity (LAST) gives rise to symptoms from the central nervous and cardiovascular systems. Knowledge about symptoms and risk factors is crucial in preventing LAST. Treatment of severe symptoms should often include vasopressors and sodium bicarbonate. In cardiac arrest the guidelines for advance life support including high-quality cardiopulmonary resuscitation (CPR) should be followed - emphasising prolonged CPR and extracorporeal life support (ECLS) in case of LAST. The conclusion of this review is that intravenous lipid emulsion should only be considered, when other interventions fail, and ECLS is unavailable.
AB - Local anaesthetic systemic toxicity (LAST) gives rise to symptoms from the central nervous and cardiovascular systems. Knowledge about symptoms and risk factors is crucial in preventing LAST. Treatment of severe symptoms should often include vasopressors and sodium bicarbonate. In cardiac arrest the guidelines for advance life support including high-quality cardiopulmonary resuscitation (CPR) should be followed - emphasising prolonged CPR and extracorporeal life support (ECLS) in case of LAST. The conclusion of this review is that intravenous lipid emulsion should only be considered, when other interventions fail, and ECLS is unavailable.
M3 - Tidsskriftartikel
C2 - 33317687
VL - 182
JO - Ugeskrift for Laeger
JF - Ugeskrift for Laeger
SN - 0041-5782
IS - 51
M1 - V11190656
ER -
ID: 269691157