Stable isotope-labeled tracers for the investigation of fatty acid and triglyceride metabolism in humans in vivo

Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt

Standard

Stable isotope-labeled tracers for the investigation of fatty acid and triglyceride metabolism in humans in vivo. / Magkos, Faidon; Mittendorfer, Bettina.

I: Clinical Lipidology, Bind 4, Nr. 2, 2009, s. 215-230.

Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt

Harvard

Magkos, F & Mittendorfer, B 2009, 'Stable isotope-labeled tracers for the investigation of fatty acid and triglyceride metabolism in humans in vivo', Clinical Lipidology, bind 4, nr. 2, s. 215-230. https://doi.org/10.2217/clp.09.9

APA

Magkos, F., & Mittendorfer, B. (2009). Stable isotope-labeled tracers for the investigation of fatty acid and triglyceride metabolism in humans in vivo. Clinical Lipidology, 4(2), 215-230. https://doi.org/10.2217/clp.09.9

Vancouver

Magkos F, Mittendorfer B. Stable isotope-labeled tracers for the investigation of fatty acid and triglyceride metabolism in humans in vivo. Clinical Lipidology. 2009;4(2):215-230. https://doi.org/10.2217/clp.09.9

Author

Magkos, Faidon ; Mittendorfer, Bettina. / Stable isotope-labeled tracers for the investigation of fatty acid and triglyceride metabolism in humans in vivo. I: Clinical Lipidology. 2009 ; Bind 4, Nr. 2. s. 215-230.

Bibtex

@article{70fb90c0aec245ecb0a3a314074aa24d,
title = "Stable isotope-labeled tracers for the investigation of fatty acid and triglyceride metabolism in humans in vivo",
abstract = "Understanding lipid metabolism and its regulation requires information on the rates at which lipids are produced within the body, absorbed (dietary lipids) into the body, transported within the body, and utilized by various tissues. This article focuses on the use of stable isotope-labeled tracers for the quantitative evaluation of major pathways of fatty acid and triglyceride metabolism in humans in vivo. Adipose tissue lipolysis and free fatty acid appearance in plasma, fatty acid tissue uptake and oxidation, and hepatic very low-density lipoprotein triglyceride secretion are among the metabolic pathways that can be studied by using stable isotope labeled tracers, and will be discussed in detail. The methodology has been in use for many years and is constantly being refined. A variety of tracers and analytical approaches are available and can be used; knowing the advantages, assumptions, and limitations of each is essential for the planning of studies and the interpretation of data, which can provide unique insights into human lipid metabolism.",
author = "Faidon Magkos and Bettina Mittendorfer",
note = "(Ekstern)",
year = "2009",
doi = "10.2217/clp.09.9",
language = "English",
volume = "4",
pages = "215--230",
journal = "Clinical Lipidology",
issn = "1758-4299",
publisher = "Future Medicine Ltd.",
number = "2",

}

RIS

TY - JOUR

T1 - Stable isotope-labeled tracers for the investigation of fatty acid and triglyceride metabolism in humans in vivo

AU - Magkos, Faidon

AU - Mittendorfer, Bettina

N1 - (Ekstern)

PY - 2009

Y1 - 2009

N2 - Understanding lipid metabolism and its regulation requires information on the rates at which lipids are produced within the body, absorbed (dietary lipids) into the body, transported within the body, and utilized by various tissues. This article focuses on the use of stable isotope-labeled tracers for the quantitative evaluation of major pathways of fatty acid and triglyceride metabolism in humans in vivo. Adipose tissue lipolysis and free fatty acid appearance in plasma, fatty acid tissue uptake and oxidation, and hepatic very low-density lipoprotein triglyceride secretion are among the metabolic pathways that can be studied by using stable isotope labeled tracers, and will be discussed in detail. The methodology has been in use for many years and is constantly being refined. A variety of tracers and analytical approaches are available and can be used; knowing the advantages, assumptions, and limitations of each is essential for the planning of studies and the interpretation of data, which can provide unique insights into human lipid metabolism.

AB - Understanding lipid metabolism and its regulation requires information on the rates at which lipids are produced within the body, absorbed (dietary lipids) into the body, transported within the body, and utilized by various tissues. This article focuses on the use of stable isotope-labeled tracers for the quantitative evaluation of major pathways of fatty acid and triglyceride metabolism in humans in vivo. Adipose tissue lipolysis and free fatty acid appearance in plasma, fatty acid tissue uptake and oxidation, and hepatic very low-density lipoprotein triglyceride secretion are among the metabolic pathways that can be studied by using stable isotope labeled tracers, and will be discussed in detail. The methodology has been in use for many years and is constantly being refined. A variety of tracers and analytical approaches are available and can be used; knowing the advantages, assumptions, and limitations of each is essential for the planning of studies and the interpretation of data, which can provide unique insights into human lipid metabolism.

U2 - 10.2217/clp.09.9

DO - 10.2217/clp.09.9

M3 - Review

C2 - 20161007

VL - 4

SP - 215

EP - 230

JO - Clinical Lipidology

JF - Clinical Lipidology

SN - 1758-4299

IS - 2

ER -

ID: 290669458