Sodium oxybate (Xyrem) treatment in severely sleep-deprived child with Epstein–Barr virus encephalitis with lesion of sleep-wake regulation system: a case report
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Sodium oxybate (Xyrem) treatment in severely sleep-deprived child with Epstein–Barr virus encephalitis with lesion of sleep-wake regulation system : a case report. / Børresen, Malene Landbo; Lundstrøm, Kaare Engell; Ifversen, Marianne; Jennum, Poul Jørgen.
I: Sleep Medicine, Bind 62, 10.2019, s. 29-31.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Sodium oxybate (Xyrem) treatment in severely sleep-deprived child with Epstein–Barr virus encephalitis with lesion of sleep-wake regulation system
T2 - a case report
AU - Børresen, Malene Landbo
AU - Lundstrøm, Kaare Engell
AU - Ifversen, Marianne
AU - Jennum, Poul Jørgen
PY - 2019/10
Y1 - 2019/10
N2 - We present the effect of exogenous sodium oxybate (GHB) in a severely tormented boy unable to sleep and unable to be anesthetized due to a lesion in the sleep initiation system involving the tracks between the ventrolateral preoptic nucleus and the reticular system. We bypassed the system by using sodium oxybate's effect on the cortical GHB and GABAB receptors involved in the initiation and maintenance of sleep.
AB - We present the effect of exogenous sodium oxybate (GHB) in a severely tormented boy unable to sleep and unable to be anesthetized due to a lesion in the sleep initiation system involving the tracks between the ventrolateral preoptic nucleus and the reticular system. We bypassed the system by using sodium oxybate's effect on the cortical GHB and GABAB receptors involved in the initiation and maintenance of sleep.
KW - Duncan's disease
KW - GABA
KW - Gamma-hydroxybutyrate
KW - GHB
KW - Hemophagocytic lymphohistiocytosis
KW - X-linked lymphoproliferative disease (XLP)
U2 - 10.1016/j.sleep.2019.03.020
DO - 10.1016/j.sleep.2019.03.020
M3 - Journal article
C2 - 31526967
AN - SCOPUS:85072214912
VL - 62
SP - 29
EP - 31
JO - Sleep Medicine
JF - Sleep Medicine
SN - 1389-9457
ER -
ID: 241998012