Short- and Long-Term Outcomes After Multimodal Treatment of Pancreatic Duct Leakage in Patients With Chronic Pancreatitis

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Standard

Short- and Long-Term Outcomes After Multimodal Treatment of Pancreatic Duct Leakage in Patients With Chronic Pancreatitis. / Roug, Stine; Novovic, Srdan; Hansen, Erik Feldager; Hadi, Amer; Schmidt, Palle Nordblad; Jørgensen, Henrik Løvendahl; Karstensen, John Gàsdal.

I: Pancreas, Bind 51, Nr. 10, 2023, s. 1315-1319.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Roug, S, Novovic, S, Hansen, EF, Hadi, A, Schmidt, PN, Jørgensen, HL & Karstensen, JG 2023, 'Short- and Long-Term Outcomes After Multimodal Treatment of Pancreatic Duct Leakage in Patients With Chronic Pancreatitis', Pancreas, bind 51, nr. 10, s. 1315-1319. https://doi.org/10.1097/MPA.0000000000002196

APA

Roug, S., Novovic, S., Hansen, E. F., Hadi, A., Schmidt, P. N., Jørgensen, H. L., & Karstensen, J. G. (2023). Short- and Long-Term Outcomes After Multimodal Treatment of Pancreatic Duct Leakage in Patients With Chronic Pancreatitis. Pancreas, 51(10), 1315-1319. https://doi.org/10.1097/MPA.0000000000002196

Vancouver

Roug S, Novovic S, Hansen EF, Hadi A, Schmidt PN, Jørgensen HL o.a. Short- and Long-Term Outcomes After Multimodal Treatment of Pancreatic Duct Leakage in Patients With Chronic Pancreatitis. Pancreas. 2023;51(10):1315-1319. https://doi.org/10.1097/MPA.0000000000002196

Author

Roug, Stine ; Novovic, Srdan ; Hansen, Erik Feldager ; Hadi, Amer ; Schmidt, Palle Nordblad ; Jørgensen, Henrik Løvendahl ; Karstensen, John Gàsdal. / Short- and Long-Term Outcomes After Multimodal Treatment of Pancreatic Duct Leakage in Patients With Chronic Pancreatitis. I: Pancreas. 2023 ; Bind 51, Nr. 10. s. 1315-1319.

Bibtex

@article{efe73c5d57394d199a2fcd7354824c29,

title = "Short- and Long-Term Outcomes After Multimodal Treatment of Pancreatic Duct Leakage in Patients With Chronic Pancreatitis",

abstract = "OBJECTIVES: In patients with chronic pancreatitis, pancreatic duct leakage is associated with a prolonged disease course and serious complications. We aimed to assess the efficacy of this multimodal treatment of pancreatic duct leakage.METHODS: In a retrospective design, patients with chronic pancreatitis, an amylase content greater than 200 U/L in either ascites or pleural fluid and treated between 2011 and 2020, were evaluated. The primary end point was treatment success.RESULTS: Twenty-seven patients (22 males, median age 60, median American Society of Anesthesiologists score 3) were included.Endoscopic retrograde pancreatography was performed in 23 patients (85%) with transpapillary stenting of the main pancreatic duct in 22 patients (96%). Pancreatic sphincterotomy and dilation of the main pancreatic duct were done in 14 patients (61%) and 17 patients (74%), respectively. Twelve patients (44%) were treated with somatostatin analogs, parenteral nutrition, and were {"}nil by mouth{"} for a median of 11 days (range, 4-34 days). Six patients (22%) had extracorporeal shock wave lithotripsy due to pancreatic duct stones. One patient (4%) was referred for surgery. All 23 patients (100%) were treated with success after a median of 21 days (range, 5-80 days).CONCLUSIONS: Multimodal treatment of pancreatic duct leakage is effective, with minimal need for surgery.",

keywords = "Male, Humans, Middle Aged, Cholangiopancreatography, Endoscopic Retrograde, Retrospective Studies, Calculi/complications, Pancreatic Diseases/therapy, Pancreatitis, Chronic/complications, Pancreatic Ducts/surgery, Lithotripsy, Treatment Outcome, Combined Modality Therapy",

author = "Stine Roug and Srdan Novovic and Hansen, {Erik Feldager} and Amer Hadi and Schmidt, {Palle Nordblad} and J{\o}rgensen, {Henrik L{\o}vendahl} and Karstensen, {John G{\`a}sdal}",

year = "2023",

doi = "10.1097/MPA.0000000000002196",

language = "English",

volume = "51",

pages = "1315--1319",

journal = "Pancreas",

issn = "0885-3177",

publisher = "Lippincott Williams & Wilkins",

number = "10",

}

RIS

TY - JOUR

T1 - Short- and Long-Term Outcomes After Multimodal Treatment of Pancreatic Duct Leakage in Patients With Chronic Pancreatitis

AU - Roug, Stine

AU - Novovic, Srdan

AU - Hansen, Erik Feldager

AU - Hadi, Amer

AU - Schmidt, Palle Nordblad

AU - Jørgensen, Henrik Løvendahl

AU - Karstensen, John Gàsdal

PY - 2023

Y1 - 2023

N2 - OBJECTIVES: In patients with chronic pancreatitis, pancreatic duct leakage is associated with a prolonged disease course and serious complications. We aimed to assess the efficacy of this multimodal treatment of pancreatic duct leakage.METHODS: In a retrospective design, patients with chronic pancreatitis, an amylase content greater than 200 U/L in either ascites or pleural fluid and treated between 2011 and 2020, were evaluated. The primary end point was treatment success.RESULTS: Twenty-seven patients (22 males, median age 60, median American Society of Anesthesiologists score 3) were included.Endoscopic retrograde pancreatography was performed in 23 patients (85%) with transpapillary stenting of the main pancreatic duct in 22 patients (96%). Pancreatic sphincterotomy and dilation of the main pancreatic duct were done in 14 patients (61%) and 17 patients (74%), respectively. Twelve patients (44%) were treated with somatostatin analogs, parenteral nutrition, and were "nil by mouth" for a median of 11 days (range, 4-34 days). Six patients (22%) had extracorporeal shock wave lithotripsy due to pancreatic duct stones. One patient (4%) was referred for surgery. All 23 patients (100%) were treated with success after a median of 21 days (range, 5-80 days).CONCLUSIONS: Multimodal treatment of pancreatic duct leakage is effective, with minimal need for surgery.

AB - OBJECTIVES: In patients with chronic pancreatitis, pancreatic duct leakage is associated with a prolonged disease course and serious complications. We aimed to assess the efficacy of this multimodal treatment of pancreatic duct leakage.METHODS: In a retrospective design, patients with chronic pancreatitis, an amylase content greater than 200 U/L in either ascites or pleural fluid and treated between 2011 and 2020, were evaluated. The primary end point was treatment success.RESULTS: Twenty-seven patients (22 males, median age 60, median American Society of Anesthesiologists score 3) were included.Endoscopic retrograde pancreatography was performed in 23 patients (85%) with transpapillary stenting of the main pancreatic duct in 22 patients (96%). Pancreatic sphincterotomy and dilation of the main pancreatic duct were done in 14 patients (61%) and 17 patients (74%), respectively. Twelve patients (44%) were treated with somatostatin analogs, parenteral nutrition, and were "nil by mouth" for a median of 11 days (range, 4-34 days). Six patients (22%) had extracorporeal shock wave lithotripsy due to pancreatic duct stones. One patient (4%) was referred for surgery. All 23 patients (100%) were treated with success after a median of 21 days (range, 5-80 days).CONCLUSIONS: Multimodal treatment of pancreatic duct leakage is effective, with minimal need for surgery.

KW - Male

KW - Humans

KW - Middle Aged

KW - Cholangiopancreatography, Endoscopic Retrograde

KW - Retrospective Studies

KW - Calculi/complications

KW - Pancreatic Diseases/therapy

KW - Pancreatitis, Chronic/complications

KW - Pancreatic Ducts/surgery

KW - Lithotripsy

KW - Treatment Outcome

KW - Combined Modality Therapy

U2 - 10.1097/MPA.0000000000002196

DO - 10.1097/MPA.0000000000002196

M3 - Journal article

C2 - 37099772

VL - 51

SP - 1315

EP - 1319

JO - Pancreas

JF - Pancreas

SN - 0885-3177

IS - 10

ER -

ID: 393849843