Risk-reducing mastectomy and salpingo-oophorectomy in unaffected BRCA mutation carriers: uptake and timing

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Standard

Risk-reducing mastectomy and salpingo-oophorectomy in unaffected BRCA mutation carriers: uptake and timing. / Skytte, A-B; Gerdes, Anne-Marie Axø; Andersen, M K; Sunde, L; Brøndum-Nielsen, K; Waldstrøm, M; Kølvraa, S; Crüger, D; Skytte, A-B; Gerdes, A-M; Andersen, M K; Sunde, L; Brøndum-Nielsen, K; Waldstrøm, M; Kølvraa, Steen; Crüger, D.

I: Clinical Genetics, Bind 77, Nr. 4, 01.04.2010, s. 342-9.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Skytte, A-B, Gerdes, A-MA, Andersen, MK, Sunde, L, Brøndum-Nielsen, K, Waldstrøm, M, Kølvraa, S, Crüger, D, Skytte, A-B, Gerdes, A-M, Andersen, MK, Sunde, L, Brøndum-Nielsen, K, Waldstrøm, M, Kølvraa, S & Crüger, D 2010, 'Risk-reducing mastectomy and salpingo-oophorectomy in unaffected BRCA mutation carriers: uptake and timing', Clinical Genetics, bind 77, nr. 4, s. 342-9. https://doi.org/10.1111/j.1399-0004.2009.01329.x, https://doi.org/10.1111/j.1399-0004.2009.01329.x

APA

Skytte, A-B., Gerdes, A-M. A., Andersen, M. K., Sunde, L., Brøndum-Nielsen, K., Waldstrøm, M., Kølvraa, S., Crüger, D., Skytte, A-B., Gerdes, A-M., Andersen, M. K., Sunde, L., Brøndum-Nielsen, K., Waldstrøm, M., Kølvraa, S., & Crüger, D. (2010). Risk-reducing mastectomy and salpingo-oophorectomy in unaffected BRCA mutation carriers: uptake and timing. Clinical Genetics, 77(4), 342-9. https://doi.org/10.1111/j.1399-0004.2009.01329.x, https://doi.org/10.1111/j.1399-0004.2009.01329.x

Vancouver

Skytte A-B, Gerdes A-MA, Andersen MK, Sunde L, Brøndum-Nielsen K, Waldstrøm M o.a. Risk-reducing mastectomy and salpingo-oophorectomy in unaffected BRCA mutation carriers: uptake and timing. Clinical Genetics. 2010 apr. 1;77(4):342-9. https://doi.org/10.1111/j.1399-0004.2009.01329.x, https://doi.org/10.1111/j.1399-0004.2009.01329.x

Author

Skytte, A-B ; Gerdes, Anne-Marie Axø ; Andersen, M K ; Sunde, L ; Brøndum-Nielsen, K ; Waldstrøm, M ; Kølvraa, S ; Crüger, D ; Skytte, A-B ; Gerdes, A-M ; Andersen, M K ; Sunde, L ; Brøndum-Nielsen, K ; Waldstrøm, M ; Kølvraa, Steen ; Crüger, D. / Risk-reducing mastectomy and salpingo-oophorectomy in unaffected BRCA mutation carriers: uptake and timing. I: Clinical Genetics. 2010 ; Bind 77, Nr. 4. s. 342-9.

Bibtex

@article{3c08737094c111df928f000ea68e967b,
title = "Risk-reducing mastectomy and salpingo-oophorectomy in unaffected BRCA mutation carriers: uptake and timing",
abstract = "Once female carriers of a BRCA mutation are identified they have to make decisions on risk management. The aim of this study is to outline the uptake of risk-reducing surgery in the Danish population of BRCA mutation positive women and to search for factors affecting this decision. We analysed data from 306 healthy BRCA carriers with no personal history of ovarian or breast cancer. We found a 10-year uptake of 75% for risk-reducing salpingo-oophorectomy and 50% for risk-reducing mastectomy by time to event analysis. Age and childbirth influenced this decision. The uptake rate has not changed significantly over the last decade. Risk-reducing surgeries are widely acceptable among Danish BRCA mutation positive women and the uptake of prophylactic mastectomy is higher than in most other countries.",
author = "A-B Skytte and Gerdes, {Anne-Marie Ax{\o}} and Andersen, {M K} and L Sunde and K Br{\o}ndum-Nielsen and M Waldstr{\o}m and S K{\o}lvraa and D Cr{\"u}ger and A-B Skytte and A-M Gerdes and Andersen, {M K} and L Sunde and K Br{\o}ndum-Nielsen and M Waldstr{\o}m and Steen K{\o}lvraa and D Cr{\"u}ger",
year = "2010",
month = apr,
day = "1",
doi = "10.1111/j.1399-0004.2009.01329.x",
language = "English",
volume = "77",
pages = "342--9",
journal = "Clinical Genetics",
issn = "0009-9163",
publisher = "Wiley-Blackwell",
number = "4",

}

RIS

TY - JOUR

T1 - Risk-reducing mastectomy and salpingo-oophorectomy in unaffected BRCA mutation carriers: uptake and timing

AU - Skytte, A-B

AU - Gerdes, Anne-Marie Axø

AU - Andersen, M K

AU - Sunde, L

AU - Brøndum-Nielsen, K

AU - Waldstrøm, M

AU - Kølvraa, S

AU - Crüger, D

AU - Skytte, A-B

AU - Gerdes, A-M

AU - Andersen, M K

AU - Sunde, L

AU - Brøndum-Nielsen, K

AU - Waldstrøm, M

AU - Kølvraa, Steen

AU - Crüger, D

PY - 2010/4/1

Y1 - 2010/4/1

N2 - Once female carriers of a BRCA mutation are identified they have to make decisions on risk management. The aim of this study is to outline the uptake of risk-reducing surgery in the Danish population of BRCA mutation positive women and to search for factors affecting this decision. We analysed data from 306 healthy BRCA carriers with no personal history of ovarian or breast cancer. We found a 10-year uptake of 75% for risk-reducing salpingo-oophorectomy and 50% for risk-reducing mastectomy by time to event analysis. Age and childbirth influenced this decision. The uptake rate has not changed significantly over the last decade. Risk-reducing surgeries are widely acceptable among Danish BRCA mutation positive women and the uptake of prophylactic mastectomy is higher than in most other countries.

AB - Once female carriers of a BRCA mutation are identified they have to make decisions on risk management. The aim of this study is to outline the uptake of risk-reducing surgery in the Danish population of BRCA mutation positive women and to search for factors affecting this decision. We analysed data from 306 healthy BRCA carriers with no personal history of ovarian or breast cancer. We found a 10-year uptake of 75% for risk-reducing salpingo-oophorectomy and 50% for risk-reducing mastectomy by time to event analysis. Age and childbirth influenced this decision. The uptake rate has not changed significantly over the last decade. Risk-reducing surgeries are widely acceptable among Danish BRCA mutation positive women and the uptake of prophylactic mastectomy is higher than in most other countries.

U2 - 10.1111/j.1399-0004.2009.01329.x

DO - 10.1111/j.1399-0004.2009.01329.x

M3 - Journal article

C2 - 20059483

VL - 77

SP - 342

EP - 349

JO - Clinical Genetics

JF - Clinical Genetics

SN - 0009-9163

IS - 4

ER -

ID: 20947437