Risici ved brug af selektive serotoningenoptagelseshæmmere til gravide
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Risici ved brug af selektive serotoningenoptagelseshæmmere til gravide. / Martens, Terje; Damkier, Per; Videbech, Poul.
I: Ugeskrift for Laeger, Bind 181, Nr. 49, V06190338, 2019.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Risici ved brug af selektive serotoningenoptagelseshæmmere til gravide
AU - Martens, Terje
AU - Damkier, Per
AU - Videbech, Poul
PY - 2019
Y1 - 2019
N2 - Depression in pregnancy is common and may have serious consequences for the mother and foetus when untreated. In this review, we discuss selective serotonin reuptake inhibitor (SSRI) intake in pregnancy, which has been associated with increased risk of several unwanted events. However, the evidence indicating a causal relationship between the intake of SSRI in pregnancy and most investigated outcomes is of very low certainty. Confounding by indication likely accounts for most of the observed correlations. If, for any outcomes, an increased risk exists, the number needed to harm is high, and the clinical significance is unclear.
AB - Depression in pregnancy is common and may have serious consequences for the mother and foetus when untreated. In this review, we discuss selective serotonin reuptake inhibitor (SSRI) intake in pregnancy, which has been associated with increased risk of several unwanted events. However, the evidence indicating a causal relationship between the intake of SSRI in pregnancy and most investigated outcomes is of very low certainty. Confounding by indication likely accounts for most of the observed correlations. If, for any outcomes, an increased risk exists, the number needed to harm is high, and the clinical significance is unclear.
M3 - Tidsskriftartikel
C2 - 31791474
VL - 181
JO - Ugeskrift for Laeger
JF - Ugeskrift for Laeger
SN - 0041-5782
IS - 49
M1 - V06190338
ER -
ID: 238526051