Referral Patterns for Patients with Nonalcoholic Fatty Liver Disease
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Referral Patterns for Patients with Nonalcoholic Fatty Liver Disease. / Rashu, Elias Badal; Werge, Mikkel Parsberg; Hetland, Liv Eline; Junker, Anders Ellekaer; Jensen, Majken Karoline; Gluud, Lise Lotte.
I: Journal of Clinical Medicine, Bind 10, Nr. 3, 404, 2021.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Referral Patterns for Patients with Nonalcoholic Fatty Liver Disease
AU - Rashu, Elias Badal
AU - Werge, Mikkel Parsberg
AU - Hetland, Liv Eline
AU - Junker, Anders Ellekaer
AU - Jensen, Majken Karoline
AU - Gluud, Lise Lotte
PY - 2021
Y1 - 2021
N2 - The incidence of nonalcoholic fatty liver disease (NAFLD) is rapidly increasing. This study evaluates the referral pattern of patients with NAFLD. A cohort study evaluating all patients with NAFLD referred to a single Gastroenterology Department from January 2017 to June 2020. Electronic patient referral letters were reviewed, and patients with NAFLD were diagnosed using standardized tests as part of a prospective cohort study. Predictors of nonalcoholic steatohepatitis (NASH) with significant (>= F2) fibrosis were evaluated in logistic regression analyses. In total, 323 (18.6%) of 1735 patients referred to the Gastro Unit during the study period were diagnosed with NAFLD. Patients were referred from general practitioners (62.5%) or other hospital departments (37.5%). Most referral letters included information suggesting a possible diagnosis of NAFLD (patient history, blood tests, or diagnostic imaging) or used the nonspecific general diagnosis suspected disease (Z.038). Out of 110 patients referred for a liver biopsy, 71 (22%) had NASH with significant fibrosis (F2 n = 39, F3 n = 19, F4 n = 13). Thirty-nine of these patients were referred from the primary sector. A logistic regression analysis (adjusted for age and gender) including all 323 patients showed that type 2 diabetes was the only significant independent predictor of NASH with fibrosis.
AB - The incidence of nonalcoholic fatty liver disease (NAFLD) is rapidly increasing. This study evaluates the referral pattern of patients with NAFLD. A cohort study evaluating all patients with NAFLD referred to a single Gastroenterology Department from January 2017 to June 2020. Electronic patient referral letters were reviewed, and patients with NAFLD were diagnosed using standardized tests as part of a prospective cohort study. Predictors of nonalcoholic steatohepatitis (NASH) with significant (>= F2) fibrosis were evaluated in logistic regression analyses. In total, 323 (18.6%) of 1735 patients referred to the Gastro Unit during the study period were diagnosed with NAFLD. Patients were referred from general practitioners (62.5%) or other hospital departments (37.5%). Most referral letters included information suggesting a possible diagnosis of NAFLD (patient history, blood tests, or diagnostic imaging) or used the nonspecific general diagnosis suspected disease (Z.038). Out of 110 patients referred for a liver biopsy, 71 (22%) had NASH with significant fibrosis (F2 n = 39, F3 n = 19, F4 n = 13). Thirty-nine of these patients were referred from the primary sector. A logistic regression analysis (adjusted for age and gender) including all 323 patients showed that type 2 diabetes was the only significant independent predictor of NASH with fibrosis.
KW - cohort study
KW - non-alcoholic steatohepatitis
KW - cirrhosis
KW - gastroenterology
KW - hepatology
KW - type 2 diabetes
KW - metabolic syndrome
U2 - 10.3390/jcm10030404
DO - 10.3390/jcm10030404
M3 - Journal article
C2 - 33494361
VL - 10
JO - Journal of Clinical Medicine
JF - Journal of Clinical Medicine
SN - 2077-0383
IS - 3
M1 - 404
ER -
ID: 257407140