Reduceret cerebralt stofskifte korrelerer med MRI-forandringer og kognitiv dysfunktion hos patienter med dissemineret sklerose
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Reduceret cerebralt stofskifte korrelerer med MRI-forandringer og kognitiv dysfunktion hos patienter med dissemineret sklerose. / Blinkenberg, M; Rune, K; Jensen, C V; Ravnborg, M H; Kyllingsbæk, Søren; Holm, S; Paulson, O B; Sørensen, P S.
I: Ugeskrift for Laeger, Bind 163, Nr. 27, 02.07.2001, s. 3788-92.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Reduceret cerebralt stofskifte korrelerer med MRI-forandringer og kognitiv dysfunktion hos patienter med dissemineret sklerose
AU - Blinkenberg, M
AU - Rune, K
AU - Jensen, C V
AU - Ravnborg, M H
AU - Kyllingsbæk, Søren
AU - Holm, S
AU - Paulson, O B
AU - Sørensen, P S
N1 - Reduced metabolism in cerebral cortex correlates with MRI changes and cognitive dysfunction in patients with disseminated sclerosis
PY - 2001/7/2
Y1 - 2001/7/2
N2 - Magnetic resonance imaging (MRI) lesion load is widely used in the clinical evaluation of patients with multiple sclerosis (MS), but little is known about the associated changes in cortical activation. For this purpose, we studied the association between the corticocerebral metabolic rate of glucose (CMRglc) and the MRI T2-weighted total lesion area (TLA). In addition, we investigated the correlation between cognitive and neurological disability and CMRglc.
AB - Magnetic resonance imaging (MRI) lesion load is widely used in the clinical evaluation of patients with multiple sclerosis (MS), but little is known about the associated changes in cortical activation. For this purpose, we studied the association between the corticocerebral metabolic rate of glucose (CMRglc) and the MRI T2-weighted total lesion area (TLA). In addition, we investigated the correlation between cognitive and neurological disability and CMRglc.
KW - Adult
KW - Aged
KW - Cerebral Cortex
KW - Cognition Disorders
KW - Deoxyglucose
KW - Evoked Potentials, Motor
KW - Female
KW - Glucose
KW - Humans
KW - Magnetic Resonance Imaging
KW - Male
KW - Middle Aged
KW - Multiple Sclerosis
KW - Neuropsychological Tests
KW - Tomography, Emission-Computed
M3 - Tidsskriftartikel
C2 - 11466987
VL - 163
SP - 3788
EP - 3792
JO - Ugeskrift for Laeger
JF - Ugeskrift for Laeger
SN - 0041-5782
IS - 27
ER -
ID: 32640193