Redo Transcatheter Aortic Valve Implantation with the ALLEGRA Transcatheter Heart Valve

Redo Transcatheter Aortic Valve Implantation with the ALLEGRA Transcatheter Heart Valve: Insights from Bench Testing

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Standard

Redo Transcatheter Aortic Valve Implantation with the ALLEGRA Transcatheter Heart Valve : Insights from Bench Testing. / Akodad, Mariama; Kütting, Maximilian; Sellers, Stephanie; Kirsten, Alina; Marx, Philipp; Kim, Isabel; Cheung, Anson; Leipsic, Jonathon; Søndergaard, Lars; Toggweiler, Stefan; Wood, David A.; Webb, John G.; Sathananthan, Janarthanan.

I: Cardiovascular Engineering and Technology, Bind 13, Nr. 6, 2022, s. 930-938.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Akodad, M, Kütting, M, Sellers, S, Kirsten, A, Marx, P, Kim, I, Cheung, A, Leipsic, J, Søndergaard, L, Toggweiler, S, Wood, DA, Webb, JG & Sathananthan, J 2022, 'Redo Transcatheter Aortic Valve Implantation with the ALLEGRA Transcatheter Heart Valve: Insights from Bench Testing', Cardiovascular Engineering and Technology, bind 13, nr. 6, s. 930-938. https://doi.org/10.1007/s13239-022-00627-1

APA

Akodad, M., Kütting, M., Sellers, S., Kirsten, A., Marx, P., Kim, I., Cheung, A., Leipsic, J., Søndergaard, L., Toggweiler, S., Wood, D. A., Webb, J. G., & Sathananthan, J. (2022). Redo Transcatheter Aortic Valve Implantation with the ALLEGRA Transcatheter Heart Valve: Insights from Bench Testing. Cardiovascular Engineering and Technology, 13(6), 930-938. https://doi.org/10.1007/s13239-022-00627-1

Vancouver

Akodad M, Kütting M, Sellers S, Kirsten A, Marx P, Kim I o.a. Redo Transcatheter Aortic Valve Implantation with the ALLEGRA Transcatheter Heart Valve: Insights from Bench Testing. Cardiovascular Engineering and Technology. 2022;13(6):930-938. https://doi.org/10.1007/s13239-022-00627-1

Author

Akodad, Mariama ; Kütting, Maximilian ; Sellers, Stephanie ; Kirsten, Alina ; Marx, Philipp ; Kim, Isabel ; Cheung, Anson ; Leipsic, Jonathon ; Søndergaard, Lars ; Toggweiler, Stefan ; Wood, David A. ; Webb, John G. ; Sathananthan, Janarthanan. / Redo Transcatheter Aortic Valve Implantation with the ALLEGRA Transcatheter Heart Valve : Insights from Bench Testing. I: Cardiovascular Engineering and Technology. 2022 ; Bind 13, Nr. 6. s. 930-938.

Bibtex

@article{f395274a4be447b3bdeccf8f606c5c62,

title = "Redo Transcatheter Aortic Valve Implantation with the ALLEGRA Transcatheter Heart Valve: Insights from Bench Testing",

abstract = "Purpose: Failure of transcatheter heart valves (THV) may potentially be treated with repeat transcatheter aortic valve implantation (redo TAVI). We assessed hydrodynamic performance, stability and pinwheeling utilizing the ALLEGRA (New Valve Technology, Hechingen, Germany) THV, a CE approved and marketed THV in Europe, inside different THVs. Methods: Redo TAVI was simulated with the 27 mm ALLEGRA THV at three implantation depths (−4 mm, 0 mm and +4 mm) in seven different {\textquoteleft}failed{\textquoteright} THVs: 26 mm Evolut Pro, 25 mm Lotus, 25 mm JenaValve, 25 mm Portico, 23 mm Sapien 3, 27 mm ALLEGRA and M ACURATE neo. Hydrodynamic evaluation was performed according to International Standards Organization 5840-3:2021. Results: The ALLEGRA THV was stable with acceptable performance (gradient <20 mmHg, effective orifice area >2 cm2, and regurgitant fraction <20%) in all {\textquoteleft}failed{\textquoteright} THVs except the Evolut Pro at −4 mm implantation depth. In this configuration, the outflow of the ALLEGRA frame was constrained by the Evolut Pro THV and the ALLEGRA leaflets were unable to fully close. Pinwheeling was severe for the ALLEGRA in Evolut Pro. The neo-skirt was higher with taller frame THVs. Conclusion: The ALLEGRA THV had favorable hydrodynamic performance, stability and pinwheeling in all redo TAVI samples except the Evolut Pro at low implantation depth with compromised function. The choice of initial THV may have late implications on new THV choice and function.",

keywords = "ALLEGRA, Aortic stenosis, Bench, Experimental, Redo TAVI, TAVI",

author = "Mariama Akodad and Maximilian K{\"u}tting and Stephanie Sellers and Alina Kirsten and Philipp Marx and Isabel Kim and Anson Cheung and Jonathon Leipsic and Lars S{\o}ndergaard and Stefan Toggweiler and Wood, {David A.} and Webb, {John G.} and Janarthanan Sathananthan",

note = "Publisher Copyright: {\textcopyright} 2022, The Author(s) under exclusive licence to Biomedical Engineering Society.",

year = "2022",

doi = "10.1007/s13239-022-00627-1",

language = "English",

volume = "13",

pages = "930--938",

journal = "Cardiovascular Engineering and Technology",

issn = "1869-408X",

publisher = "Springer Publishing Company",

number = "6",

}

RIS

TY - JOUR

T1 - Redo Transcatheter Aortic Valve Implantation with the ALLEGRA Transcatheter Heart Valve

T2 - Insights from Bench Testing

AU - Akodad, Mariama

AU - Kütting, Maximilian

AU - Sellers, Stephanie

AU - Kirsten, Alina

AU - Marx, Philipp

AU - Kim, Isabel

AU - Cheung, Anson

AU - Leipsic, Jonathon

AU - Søndergaard, Lars

AU - Toggweiler, Stefan

AU - Wood, David A.

AU - Webb, John G.

AU - Sathananthan, Janarthanan

PY - 2022

Y1 - 2022

N2 - Purpose: Failure of transcatheter heart valves (THV) may potentially be treated with repeat transcatheter aortic valve implantation (redo TAVI). We assessed hydrodynamic performance, stability and pinwheeling utilizing the ALLEGRA (New Valve Technology, Hechingen, Germany) THV, a CE approved and marketed THV in Europe, inside different THVs. Methods: Redo TAVI was simulated with the 27 mm ALLEGRA THV at three implantation depths (−4 mm, 0 mm and +4 mm) in seven different ‘failed’ THVs: 26 mm Evolut Pro, 25 mm Lotus, 25 mm JenaValve, 25 mm Portico, 23 mm Sapien 3, 27 mm ALLEGRA and M ACURATE neo. Hydrodynamic evaluation was performed according to International Standards Organization 5840-3:2021. Results: The ALLEGRA THV was stable with acceptable performance (gradient <20 mmHg, effective orifice area >2 cm2, and regurgitant fraction <20%) in all ‘failed’ THVs except the Evolut Pro at −4 mm implantation depth. In this configuration, the outflow of the ALLEGRA frame was constrained by the Evolut Pro THV and the ALLEGRA leaflets were unable to fully close. Pinwheeling was severe for the ALLEGRA in Evolut Pro. The neo-skirt was higher with taller frame THVs. Conclusion: The ALLEGRA THV had favorable hydrodynamic performance, stability and pinwheeling in all redo TAVI samples except the Evolut Pro at low implantation depth with compromised function. The choice of initial THV may have late implications on new THV choice and function.

AB - Purpose: Failure of transcatheter heart valves (THV) may potentially be treated with repeat transcatheter aortic valve implantation (redo TAVI). We assessed hydrodynamic performance, stability and pinwheeling utilizing the ALLEGRA (New Valve Technology, Hechingen, Germany) THV, a CE approved and marketed THV in Europe, inside different THVs. Methods: Redo TAVI was simulated with the 27 mm ALLEGRA THV at three implantation depths (−4 mm, 0 mm and +4 mm) in seven different ‘failed’ THVs: 26 mm Evolut Pro, 25 mm Lotus, 25 mm JenaValve, 25 mm Portico, 23 mm Sapien 3, 27 mm ALLEGRA and M ACURATE neo. Hydrodynamic evaluation was performed according to International Standards Organization 5840-3:2021. Results: The ALLEGRA THV was stable with acceptable performance (gradient <20 mmHg, effective orifice area >2 cm2, and regurgitant fraction <20%) in all ‘failed’ THVs except the Evolut Pro at −4 mm implantation depth. In this configuration, the outflow of the ALLEGRA frame was constrained by the Evolut Pro THV and the ALLEGRA leaflets were unable to fully close. Pinwheeling was severe for the ALLEGRA in Evolut Pro. The neo-skirt was higher with taller frame THVs. Conclusion: The ALLEGRA THV had favorable hydrodynamic performance, stability and pinwheeling in all redo TAVI samples except the Evolut Pro at low implantation depth with compromised function. The choice of initial THV may have late implications on new THV choice and function.

KW - ALLEGRA

KW - Aortic stenosis

KW - Bench

KW - Experimental

KW - Redo TAVI

KW - TAVI

U2 - 10.1007/s13239-022-00627-1

DO - 10.1007/s13239-022-00627-1

M3 - Journal article

C2 - 35505271

AN - SCOPUS:85129311760

VL - 13

SP - 930

EP - 938

JO - Cardiovascular Engineering and Technology

JF - Cardiovascular Engineering and Technology

SN - 1869-408X

IS - 6

ER -

ID: 314280078