Randomised trial of endoscopic endoprosthesis versus operative bypass in malignant obstructive jaundice.
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Randomised trial of endoscopic endoprosthesis versus operative bypass in malignant obstructive jaundice. / Andersen, J R; Sørensen, S M; Kruse, A; Rokkjaer, M; Matzen, Peter.
I: Gut, Bind 30, Nr. 8, 1989, s. 1132-1135.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning
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T1 - Randomised trial of endoscopic endoprosthesis versus operative bypass in malignant obstructive jaundice.
AU - Andersen, J R
AU - Sørensen, S M
AU - Kruse, A
AU - Rokkjaer, M
AU - Matzen, Peter
PY - 1989
Y1 - 1989
N2 - In patients with obstructive jaundice caused by malignant stricture of the extrahepatic bile duct we compared survival time, complication rates, hospitalisation requirements, and quality of life after palliation by endoscopic endoprosthesis or bypass surgery. During diagnostic endoscopic cholangiography 50 patients were randomised to the two treatment alternatives. All 25 patients randomised to endoprosthesis were treated by this procedure, whereas only 19 of 25 patients randomised to bypass surgery underwent operative biliary-digestive anastomosis. Life table analysis revealed no difference in survival between treatment groups or randomisation groups. No differences were found when other variables were compared. We conclude, that palliation of obstructive jaundice in malignant bile duct obstruction with endoscopically introduced endoprosthesis is as effective as operative bypass.
AB - In patients with obstructive jaundice caused by malignant stricture of the extrahepatic bile duct we compared survival time, complication rates, hospitalisation requirements, and quality of life after palliation by endoscopic endoprosthesis or bypass surgery. During diagnostic endoscopic cholangiography 50 patients were randomised to the two treatment alternatives. All 25 patients randomised to endoprosthesis were treated by this procedure, whereas only 19 of 25 patients randomised to bypass surgery underwent operative biliary-digestive anastomosis. Life table analysis revealed no difference in survival between treatment groups or randomisation groups. No differences were found when other variables were compared. We conclude, that palliation of obstructive jaundice in malignant bile duct obstruction with endoscopically introduced endoprosthesis is as effective as operative bypass.
M3 - Journal article
VL - 30
SP - 1132
EP - 1135
JO - Gut
JF - Gut
SN - 0017-5749
IS - 8
ER -
ID: 34189394