TY - JOUR

T1 - Proteomic Applications in Antimicrobial Resistance and Clinical Microbiology Studies

AU - Khodadadi, Ehsaneh

AU - Zeinalzadeh, Elham

AU - Taghizadeh, Sepehr

AU - Mehramouz, Bahareh

AU - Kamounah, Fadhil S

AU - Khodadadi, Ehsan

AU - Ganbarov, Khudaverdi

AU - Yousefi, Bahman

AU - Bastami, Milad

AU - Kafil, Hossein Samadi

PY - 2020

Y1 - 2020

N2 - Sequences of the genomes of all-important bacterial pathogens of man, plants, and animals have been completed. Still, it is not enough to achieve complete information of all the mechanisms controlling the biological processes of an organism. Along with all advances in different proteomics technologies, proteomics has completed our knowledge of biological processes all around the world. Proteomics is a valuable technique to explain the complement of proteins in any organism. One of the fields that has been notably benefited from other systems approaches is bacterial pathogenesis. An emerging field is to use proteomics to examine the infectious agents in terms of, among many, the response the host and pathogen to the infection process, which leads to a deeper knowledge of the mechanisms of bacterial virulence. This trend also enables us to identify quantitative measurements for proteins extracted from microorganisms. The present review study is an attempt to summarize a variety of different proteomic techniques and advances. The significant applications in bacterial pathogenesis studies are also covered. Moreover, the areas where proteomics may lead the future studies are introduced.

AB - Sequences of the genomes of all-important bacterial pathogens of man, plants, and animals have been completed. Still, it is not enough to achieve complete information of all the mechanisms controlling the biological processes of an organism. Along with all advances in different proteomics technologies, proteomics has completed our knowledge of biological processes all around the world. Proteomics is a valuable technique to explain the complement of proteins in any organism. One of the fields that has been notably benefited from other systems approaches is bacterial pathogenesis. An emerging field is to use proteomics to examine the infectious agents in terms of, among many, the response the host and pathogen to the infection process, which leads to a deeper knowledge of the mechanisms of bacterial virulence. This trend also enables us to identify quantitative measurements for proteins extracted from microorganisms. The present review study is an attempt to summarize a variety of different proteomic techniques and advances. The significant applications in bacterial pathogenesis studies are also covered. Moreover, the areas where proteomics may lead the future studies are introduced.

U2 - 10.2147/IDR.S238446

DO - 10.2147/IDR.S238446

M3 - Review

C2 - 32606829

VL - 13

SP - 1785

EP - 1806

JO - Infection and Drug Resistance

JF - Infection and Drug Resistance

SN - 1178-6973

ER -