Protein kinase C {alpha} activity is important for contraction-induced FXYD1 phosphorylation in skeletal muscle
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Exercise induced phosphorylation of FXYD1 is a potential important regulator of Na(+), K(+) pump activity. It was investigated if skeletal muscle contractions induce phosphorylation of FXYD1 and if Protein Kinase C a (PKCa) activity is a prerequisite for this possible mechanism. In part 1, human muscle biopsies were obtained at rest, after 30 s of high intensity exercise (166±31% of VO(2max)) and after a subsequent 20 min of moderate intensity exercise (79±8% of VO(2max)). In general, FXYD1 phosphorylation was increased compared to rest both after 30 s (P
Originalsprog | Engelsk |
---|---|
Tidsskrift | American Journal of Physiology: Regulatory, Integrative and Comparative Physiology |
Vol/bind | 301 |
Udgave nummer | 6 |
Sider (fra-til) | R1808-R1814 |
Antal sider | 7 |
ISSN | 0363-6119 |
DOI | |
Status | Udgivet - 2011 |
Bibliografisk note
CURIS 2011 5200 118
ID: 35089836