Phylogenetic analysis of F-bZIP transcription factors indicates conservation of the zinc deficiency response across land plants
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Dokumenter
- Phylogenetic analysis of F-bZIP transcription factors indicates conservation of the zinc deficiency response across land plants
Forlagets udgivne version, 8,42 MB, PDF-dokument
Basic leucine zipper (bZIP) transcription factors control important developmental and physiological processes in plants. In Arabidopsis thaliana, the three gene F-bZIP subfamily has been associated with zinc deficiency and salt stress response. Benefiting from the present abundance of plant genomic data, we performed an evolutionary and structural characterization of plant F-bZIPs. We observed divergence during seed plant evolution, into two groups and inferred different selective pressures for each. Group 1 contains AtbZIP19 and AtbZIP23 and appears more conserved, whereas Group 2, containing AtbZIP24, is more prone to gene loss and expansion events. Transcriptomic and experimental data reinforced AtbZIP19/23 as pivotal regulators of the zinc deficiency response, mostly via the activation of genes from the ZIP metal transporter family, and revealed that they are the main regulatory switch of AtZIP4. A survey of AtZIP4 orthologs promoters across different plant taxa revealed an enrichment of the Zinc Deficiency Response Element (ZDRE) to which both AtbZIP19/23 bind. Overall, our results indicate that while the AtbZIP24 function in the regulation of the salt stress response may be the result of neo-functionalization, the AtbZIP19/23 function in the regulation of the zinc deficiency response may be conserved in land plants (Embryophytes).
Originalsprog | Engelsk |
---|---|
Artikelnummer | 3806 |
Tidsskrift | Scientific Reports |
Vol/bind | 7 |
Udgave nummer | 1 |
Antal sider | 14 |
ISSN | 2045-2322 |
DOI | |
Status | Udgivet - 2017 |
Antal downloads er baseret på statistik fra Google Scholar og www.ku.dk
ID: 179884734