Photoacoustic tomography for assessment and quantification of cutaneous and metastatic malignant melanoma - A systematic review
Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt
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Photoacoustic tomography for assessment and quantification of cutaneous and metastatic malignant melanoma - A systematic review. / von Knorring, Terese; Mogensen, Mette.
I: Photodiagnosis and Photodynamic Therapy, Bind 33, 102095, 2021.Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt
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TY - JOUR
T1 - Photoacoustic tomography for assessment and quantification of cutaneous and metastatic malignant melanoma - A systematic review
AU - von Knorring, Terese
AU - Mogensen, Mette
N1 - Publisher Copyright: © 2020 Elsevier B.V.
PY - 2021
Y1 - 2021
N2 - Background: Photoacoustic tomography (PAT) is an emerging noninvasive imaging technique combining high sensitivity optical absorption contrast, such as melanin, with high-resolution ultrasound for deep tissue imaging. The ability of PAT to provide real-time images of skin structures at depth has been studied for diagnosis of primary and metastatic malignant melanoma (MM). Objective: To provide an overview of the rapidly expanding clinical use of PAT for determination of melanoma thickness and architecture, visualization of metastases in lymph nodes and detection of circulating melanoma cells. Methods: Medline, PubMed, EMBASE, Web of Science, Google Scholar, and Cochrane Library were searched for papers using PAT to assess cutaneous malignant melanoma and melanoma metastases in humans or human specimens. Results: The research resulted in 14 articles which met the search criteria. Conclusions: Results from current studies suggest that PAT is a promising tool for assessing both primary and metastatic malignant melanoma in the clinic. The potential of PAT to noninvasively visualize tumour boundaries, as well as assist in the evaluation of metastatic status, could facilitate more effective treatment, resulting in better clearance and reducing the need for additional biopsies. However, larger and methodologically sound studies are warranted.
AB - Background: Photoacoustic tomography (PAT) is an emerging noninvasive imaging technique combining high sensitivity optical absorption contrast, such as melanin, with high-resolution ultrasound for deep tissue imaging. The ability of PAT to provide real-time images of skin structures at depth has been studied for diagnosis of primary and metastatic malignant melanoma (MM). Objective: To provide an overview of the rapidly expanding clinical use of PAT for determination of melanoma thickness and architecture, visualization of metastases in lymph nodes and detection of circulating melanoma cells. Methods: Medline, PubMed, EMBASE, Web of Science, Google Scholar, and Cochrane Library were searched for papers using PAT to assess cutaneous malignant melanoma and melanoma metastases in humans or human specimens. Results: The research resulted in 14 articles which met the search criteria. Conclusions: Results from current studies suggest that PAT is a promising tool for assessing both primary and metastatic malignant melanoma in the clinic. The potential of PAT to noninvasively visualize tumour boundaries, as well as assist in the evaluation of metastatic status, could facilitate more effective treatment, resulting in better clearance and reducing the need for additional biopsies. However, larger and methodologically sound studies are warranted.
KW - Diagnostic imaging
KW - Malignant melanoma
KW - Multispectral optoacoustic tomography
KW - Photoacoustic imaging
KW - Raster scanning optoacoustic mesoscopy
KW - Skin cancer
U2 - 10.1016/j.pdpdt.2020.102095
DO - 10.1016/j.pdpdt.2020.102095
M3 - Review
C2 - 33188938
AN - SCOPUS:85097434805
VL - 33
JO - Photodiagnosis and Photodynamic Therapy
JF - Photodiagnosis and Photodynamic Therapy
SN - 1572-1000
M1 - 102095
ER -
ID: 303046459