Patient-reported outcomes in adult survivors with single-ventricle physiology
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Patient-reported outcomes in adult survivors with single-ventricle physiology. / Overgaard, Dorthe; Schrader, Anne-Marie; Lisby, Karen H; King, Catriona; Christensen, Rie F; Jensen, Helena F; Idorn, Lars; Søndergaard, Lars; Moons, Philip.
I: Cardiology, Bind 120, Nr. 1, 2011, s. 36-42.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Patient-reported outcomes in adult survivors with single-ventricle physiology
AU - Overgaard, Dorthe
AU - Schrader, Anne-Marie
AU - Lisby, Karen H
AU - King, Catriona
AU - Christensen, Rie F
AU - Jensen, Helena F
AU - Idorn, Lars
AU - Søndergaard, Lars
AU - Moons, Philip
N1 - Copyright © 2011 S. Karger AG, Basel.
PY - 2011
Y1 - 2011
N2 - Objectives: Data on patient-reported outcomes (PROs) in patients with single-ventricle physiology (SVP) are scarce. We sought (1) to describe the perceived health status, quality of life, symptoms of anxiety and depression, and sense of coherence in adult survivors with SVP, (2) to compare PROs across functional classes, and (3) to compare PROs between patients and controls. Methods: A case-control study in two adult congenital heart programmes with 62 adult survivors with SVP were matched to 172 healthy controls. A wide range of PROs were measured using validated questionnaires. The treating physician classified patients according to the Ability Index. Results: Patients with SVP have a good functional status. Patients in Ability Index class I consistently reported the best scores, similar to those of healthy controls. Negative associations were found between functional class and outcomes of perceived health and quality of life. For patients in Ability Index class II and III, PROs were poorer. Conclusions: PROs in patients with SVP are generally good.
AB - Objectives: Data on patient-reported outcomes (PROs) in patients with single-ventricle physiology (SVP) are scarce. We sought (1) to describe the perceived health status, quality of life, symptoms of anxiety and depression, and sense of coherence in adult survivors with SVP, (2) to compare PROs across functional classes, and (3) to compare PROs between patients and controls. Methods: A case-control study in two adult congenital heart programmes with 62 adult survivors with SVP were matched to 172 healthy controls. A wide range of PROs were measured using validated questionnaires. The treating physician classified patients according to the Ability Index. Results: Patients with SVP have a good functional status. Patients in Ability Index class I consistently reported the best scores, similar to those of healthy controls. Negative associations were found between functional class and outcomes of perceived health and quality of life. For patients in Ability Index class II and III, PROs were poorer. Conclusions: PROs in patients with SVP are generally good.
U2 - 10.1159/000333112
DO - 10.1159/000333112
M3 - Journal article
C2 - 22094965
VL - 120
SP - 36
EP - 42
JO - Cardiologia
JF - Cardiologia
SN - 0008-6312
IS - 1
ER -
ID: 40225193