Patient education with or without manual therapy compared to a control group in patients with osteoarthritis of the hip. A proof-of-principle three-arm parallel group randomized clinical trial
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Patient education with or without manual therapy compared to a control group in patients with osteoarthritis of the hip. A proof-of-principle three-arm parallel group randomized clinical trial. / Poulsen, E; Hartvigsen, J; Christensen, H W; Roos, Ewa M.; Vach, W; Overgaard, Søren.
I: Osteoarthritis and Cartilage, Bind 21, Nr. 10, 10.2013, s. 1494-1503.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Patient education with or without manual therapy compared to a control group in patients with osteoarthritis of the hip. A proof-of-principle three-arm parallel group randomized clinical trial
AU - Poulsen, E
AU - Hartvigsen, J
AU - Christensen, H W
AU - Roos, Ewa M.
AU - Vach, W
AU - Overgaard, Søren
N1 - Copyright © 2013 Osteoarthritis Research Society International. Published by Elsevier Ltd. All rights reserved.
PY - 2013/10
Y1 - 2013/10
N2 - Objective: To investigate the effectiveness of a patient education (PE) program with or without the added effect of manual therapy (MT) compared to a minimal control intervention (MCI). Methods: In a single-center university hospital setting, a total of 118 patients with clinical and radiographic unilateral hip osteoarthritis (OA) from primary care were randomized into one of three groups: PE, PE plus MT or MCI. The PE was taught by a physiotherapist involving five sessions. The MT was delivered by a chiropractor involving 12 sessions and the MCI included a home stretching program. Primary outcome was self-reported pain severity on an 11-box numeric rating scale (NRS) immediately following a 6-week intervention period. Patients were followed for 1 year. Results: Primary analysis included 111 patients (94%). In the combined group (PE+MT), a clinically relevant reduction in pain severity compared to the MCI of 1.90 points (95% confidence interval (CI) 0.9-2.9) was achieved. Effect size (Cohen's d) for the PE+MT minus the MCI was 0.92 (95% CI 0.41-1.42). Number needed to treat for PE+MT was 3 (95% CI 2-7). No difference was found between the PE and MCI groups, with mean difference 0.0 (95% CI-1.0 to 1.0). At 12 months, not including patients receiving hip surgery the statistically significant difference favoring PE+MT was maintained. Conclusions: For primary care patients with OA of the hip, a combined intervention of MT and PE was more effective than a MCI. PE alone was not superior to the MCI. Trial registration: clinicaltrials.gov NCT01039337.
AB - Objective: To investigate the effectiveness of a patient education (PE) program with or without the added effect of manual therapy (MT) compared to a minimal control intervention (MCI). Methods: In a single-center university hospital setting, a total of 118 patients with clinical and radiographic unilateral hip osteoarthritis (OA) from primary care were randomized into one of three groups: PE, PE plus MT or MCI. The PE was taught by a physiotherapist involving five sessions. The MT was delivered by a chiropractor involving 12 sessions and the MCI included a home stretching program. Primary outcome was self-reported pain severity on an 11-box numeric rating scale (NRS) immediately following a 6-week intervention period. Patients were followed for 1 year. Results: Primary analysis included 111 patients (94%). In the combined group (PE+MT), a clinically relevant reduction in pain severity compared to the MCI of 1.90 points (95% confidence interval (CI) 0.9-2.9) was achieved. Effect size (Cohen's d) for the PE+MT minus the MCI was 0.92 (95% CI 0.41-1.42). Number needed to treat for PE+MT was 3 (95% CI 2-7). No difference was found between the PE and MCI groups, with mean difference 0.0 (95% CI-1.0 to 1.0). At 12 months, not including patients receiving hip surgery the statistically significant difference favoring PE+MT was maintained. Conclusions: For primary care patients with OA of the hip, a combined intervention of MT and PE was more effective than a MCI. PE alone was not superior to the MCI. Trial registration: clinicaltrials.gov NCT01039337.
U2 - 10.1016/j.joca.2013.06.009
DO - 10.1016/j.joca.2013.06.009
M3 - Journal article
C2 - 23792189
VL - 21
SP - 1494
EP - 1503
JO - Osteoarthritis and Cartilage
JF - Osteoarthritis and Cartilage
SN - 1063-4584
IS - 10
ER -
ID: 252063226