Overcoming Treatment Toxicity through Sequential Therapy
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Overcoming Treatment Toxicity through Sequential Therapy. / Benada, Jan; Ejlertsen, Bent; Sørensen, Claus Storgaard.
I: Cancer Cell, Bind 35, Nr. 6, 2019, s. 821-822.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning
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TY - JOUR
T1 - Overcoming Treatment Toxicity through Sequential Therapy
AU - Benada, Jan
AU - Ejlertsen, Bent
AU - Sørensen, Claus Storgaard
N1 - Copyright © 2019 Elsevier Inc. All rights reserved.
PY - 2019
Y1 - 2019
N2 - Combined inhibitions of PARP and DNA damage checkpoint have the potential for high anti-cancer efficacy, but concurrent inhibitions have been hampered by intolerable side effects. In this issue of Cancer Cell, Fang and colleagues (Fang et al., 2019) propose that sequential inhibitions of PARP and DNA damage checkpoint considerably widen the therapeutic window.
AB - Combined inhibitions of PARP and DNA damage checkpoint have the potential for high anti-cancer efficacy, but concurrent inhibitions have been hampered by intolerable side effects. In this issue of Cancer Cell, Fang and colleagues (Fang et al., 2019) propose that sequential inhibitions of PARP and DNA damage checkpoint considerably widen the therapeutic window.
U2 - 10.1016/j.ccell.2019.05.006
DO - 10.1016/j.ccell.2019.05.006
M3 - Journal article
C2 - 31185206
VL - 35
SP - 821
EP - 822
JO - Cancer Cell
JF - Cancer Cell
SN - 1535-6108
IS - 6
ER -
ID: 225384566