Outstanding challenges for rotavirus vaccine introduction in low-income countries: a systematic review
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Standard
Outstanding challenges for rotavirus vaccine introduction in low-income countries : a systematic review. / Ustrup, Marte; Madsen, Lizell B; Bygbjerg, Ib C; Konradsen, Flemming.
I: Danish Medical Bulletin (Online), Bind 58, Nr. 10, 2011, s. A4323.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Harvard
APA
Vancouver
Author
Bibtex
}
RIS
TY - JOUR
T1 - Outstanding challenges for rotavirus vaccine introduction in low-income countries
T2 - a systematic review
AU - Ustrup, Marte
AU - Madsen, Lizell B
AU - Bygbjerg, Ib C
AU - Konradsen, Flemming
PY - 2011
Y1 - 2011
N2 - Rotavirus infections are the most common cause of severe diarrhoea in children worldwide. Two internationally licensed rotavirus vaccines have proven to be efficacious in middle and high-income countries and they could potentially be valuable tools for the prevention of rotavirus-associated diarrhoea in low-income countries where the disease burden is greatest. However, before the vaccines can be introduced into the national immunisation programmes in these countries, many challenges related to the financing of vaccine purchase, the cold chain capacity and vaccine efficacy must be overcome. There is also a need for political commitment to prevent rotavirus infections as well as a need for an overall strengthening of the health systems in low-income countries. If these challenges were met, rotavirus vaccination could substantially improve child health and survival from rotavirus-associated diarrhoea.
AB - Rotavirus infections are the most common cause of severe diarrhoea in children worldwide. Two internationally licensed rotavirus vaccines have proven to be efficacious in middle and high-income countries and they could potentially be valuable tools for the prevention of rotavirus-associated diarrhoea in low-income countries where the disease burden is greatest. However, before the vaccines can be introduced into the national immunisation programmes in these countries, many challenges related to the financing of vaccine purchase, the cold chain capacity and vaccine efficacy must be overcome. There is also a need for political commitment to prevent rotavirus infections as well as a need for an overall strengthening of the health systems in low-income countries. If these challenges were met, rotavirus vaccination could substantially improve child health and survival from rotavirus-associated diarrhoea.
M3 - Journal article
C2 - 21975154
VL - 58
SP - A4323
JO - Danish Medical Journal
JF - Danish Medical Journal
SN - 2245-1919
IS - 10
ER -
ID: 38504366