On the methodology of drug trials in migraine with aura
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On the methodology of drug trials in migraine with aura. / Hauge, Anne Werner; Hougaard, Anders; Olesen, Jes.
I: Cephalalgia, Bind 30, Nr. 9, 01.09.2010, s. 1041-8.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - On the methodology of drug trials in migraine with aura
AU - Hauge, Anne Werner
AU - Hougaard, Anders
AU - Olesen, Jes
PY - 2010/9/1
Y1 - 2010/9/1
N2 - INTRODUCTION: Specific problems occur in clinical treatment trials for migraine with aura that differ from those encountered in treatment trials for migraine without aura. DISCUSSION: Based on our experience with four such trials, we point to a number of possible solutions and outline areas for future inquiry. We make recommendations about subject selection; the choice, definition and assessment of outcome measures; optimal treatments in relation to aura and headache; and we provide samples of study report forms used to record occurrence of aura and headache in this population.
AB - INTRODUCTION: Specific problems occur in clinical treatment trials for migraine with aura that differ from those encountered in treatment trials for migraine without aura. DISCUSSION: Based on our experience with four such trials, we point to a number of possible solutions and outline areas for future inquiry. We make recommendations about subject selection; the choice, definition and assessment of outcome measures; optimal treatments in relation to aura and headache; and we provide samples of study report forms used to record occurrence of aura and headache in this population.
U2 - http://dx.doi.org/10.1177/0333102409359091
DO - http://dx.doi.org/10.1177/0333102409359091
M3 - Journal article
VL - 30
SP - 1041
EP - 1048
JO - Cephalalgia
JF - Cephalalgia
SN - 0800-1952
IS - 9
ER -
ID: 34083600