Novel variant of CYP2D6*6 is undetected by a commonly used genotyping procedure

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Standard

Novel variant of CYP2D6*6 is undetected by a commonly used genotyping procedure. / Rasmussen, Henrik Berg; Werge, Thomas.

I: Pharmacological Reports, Bind 63, Nr. 5, 2011, s. 1264-6.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Rasmussen, HB & Werge, T 2011, 'Novel variant of CYP2D6*6 is undetected by a commonly used genotyping procedure', Pharmacological Reports, bind 63, nr. 5, s. 1264-6.

APA

Rasmussen, H. B., & Werge, T. (2011). Novel variant of CYP2D6*6 is undetected by a commonly used genotyping procedure. Pharmacological Reports, 63(5), 1264-6.

Vancouver

Rasmussen HB, Werge T. Novel variant of CYP2D6*6 is undetected by a commonly used genotyping procedure. Pharmacological Reports. 2011;63(5):1264-6.

Author

Rasmussen, Henrik Berg ; Werge, Thomas. / Novel variant of CYP2D6*6 is undetected by a commonly used genotyping procedure. I: Pharmacological Reports. 2011 ; Bind 63, Nr. 5. s. 1264-6.

Bibtex

@article{b5bba39ddd9c42228353eb2164310885,
title = "Novel variant of CYP2D6*6 is undetected by a commonly used genotyping procedure",
abstract = "We report the identification of a novel and defective variant of the gene encoding cytochrome P450 2D6 (CYP2D6). This novel variant is a subtype of CYP2D6*6 that was undetected by a commercially available 5' exonuclease-based assay. Because the novel variant was found in only one of 609 individuals, it represents a rare subtype of CYP2D6*6 that may be restricted to a single family or a subpopulation. A procedure for the identification of the novel CYP2D6*6 variant using restriction enzyme treatment of amplified fragments was developed.",
author = "Rasmussen, {Henrik Berg} and Thomas Werge",
year = "2011",
language = "English",
volume = "63",
pages = "1264--6",
journal = "Pharmacological Reports",
issn = "1734-1140",
publisher = "Elsevier Urban & Partner Sp. z o.o.",
number = "5",

}

RIS

TY - JOUR

T1 - Novel variant of CYP2D6*6 is undetected by a commonly used genotyping procedure

AU - Rasmussen, Henrik Berg

AU - Werge, Thomas

PY - 2011

Y1 - 2011

N2 - We report the identification of a novel and defective variant of the gene encoding cytochrome P450 2D6 (CYP2D6). This novel variant is a subtype of CYP2D6*6 that was undetected by a commercially available 5' exonuclease-based assay. Because the novel variant was found in only one of 609 individuals, it represents a rare subtype of CYP2D6*6 that may be restricted to a single family or a subpopulation. A procedure for the identification of the novel CYP2D6*6 variant using restriction enzyme treatment of amplified fragments was developed.

AB - We report the identification of a novel and defective variant of the gene encoding cytochrome P450 2D6 (CYP2D6). This novel variant is a subtype of CYP2D6*6 that was undetected by a commercially available 5' exonuclease-based assay. Because the novel variant was found in only one of 609 individuals, it represents a rare subtype of CYP2D6*6 that may be restricted to a single family or a subpopulation. A procedure for the identification of the novel CYP2D6*6 variant using restriction enzyme treatment of amplified fragments was developed.

M3 - Journal article

VL - 63

SP - 1264

EP - 1266

JO - Pharmacological Reports

JF - Pharmacological Reports

SN - 1734-1140

IS - 5

ER -

ID: 40205201