Normal sweat secretion despite impaired growth hormone-insulin-like growth factor-I axis in obese subjects

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Standard

Normal sweat secretion despite impaired growth hormone-insulin-like growth factor-I axis in obese subjects. / Rasmussen, M H; Juul, Anders; Main, Katharina M; Hilsted, Jannik; Rasmussen, Michael Højby.

I: International Journal of Endocrinology, Bind 2011, 2011, s. 493840.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Rasmussen, MH, Juul, A, Main, KM, Hilsted, J & Rasmussen, MH 2011, 'Normal sweat secretion despite impaired growth hormone-insulin-like growth factor-I axis in obese subjects', International Journal of Endocrinology, bind 2011, s. 493840. https://doi.org/ 10.1155/2011/493840, https://doi.org/10.1155/2011/493840

APA

Rasmussen, M. H., Juul, A., Main, K. M., Hilsted, J., & Rasmussen, M. H. (2011). Normal sweat secretion despite impaired growth hormone-insulin-like growth factor-I axis in obese subjects. International Journal of Endocrinology, 2011, 493840. https://doi.org/ 10.1155/2011/493840, https://doi.org/10.1155/2011/493840

Vancouver

Rasmussen MH, Juul A, Main KM, Hilsted J, Rasmussen MH. Normal sweat secretion despite impaired growth hormone-insulin-like growth factor-I axis in obese subjects. International Journal of Endocrinology. 2011;2011:493840. https://doi.org/ 10.1155/2011/493840, https://doi.org/10.1155/2011/493840

Author

Rasmussen, M H ; Juul, Anders ; Main, Katharina M ; Hilsted, Jannik ; Rasmussen, Michael Højby. / Normal sweat secretion despite impaired growth hormone-insulin-like growth factor-I axis in obese subjects. I: International Journal of Endocrinology. 2011 ; Bind 2011. s. 493840.

Bibtex

@article{13cd462d41a242f1b6d9d3bcd83e8357,
title = "Normal sweat secretion despite impaired growth hormone-insulin-like growth factor-I axis in obese subjects",
abstract = "Adults with GH deficiency are known to exhibit reduced sweating. Whether sweating capacity is impacted in obese subjects with impaired GH secretion have not previously been investigated. The main objective was to investigate sweat secretion rate and the GH-IGF-I axis in obese subjects before and after weight loss. Sixteen severely obese women (BMI, 40.6 ± 1.1 kg/m(2)) were investigated before and after a diet-induced weight loss. Sixteen age-matched nonobese women served as controls. The obese subjects presented the characteristic decreased GH release, hyperinsulinaemia, increased FFA levels, and impaired insulin sensitivity, which all were normalised after diet-induced weight loss of 30 ± 5 kg. Sweat secretion rates were similar comparing obese and nonobese subjects (78 ± 10 versus 82 ± 9 mg/30 minutes) and sweat secretion did not change after a diet-induced weight loss in obese subjects. We conclude that although obese subjects have markedly reduced GH release and impaired IGF-I levels, sweat secretion rate is found to be normal.",
author = "Rasmussen, {M H} and Anders Juul and Main, {Katharina M} and Jannik Hilsted and Rasmussen, {Michael H{\o}jby}",
year = "2011",
doi = "http://dx.doi.org/ 10.1155/2011/493840",
language = "English",
volume = "2011",
pages = "493840",
journal = "International Journal of Endocrinology",
issn = "1687-8337",
publisher = "Hindawi Publishing Corporation",

}

RIS

TY - JOUR

T1 - Normal sweat secretion despite impaired growth hormone-insulin-like growth factor-I axis in obese subjects

AU - Rasmussen, M H

AU - Juul, Anders

AU - Main, Katharina M

AU - Hilsted, Jannik

AU - Rasmussen, Michael Højby

PY - 2011

Y1 - 2011

N2 - Adults with GH deficiency are known to exhibit reduced sweating. Whether sweating capacity is impacted in obese subjects with impaired GH secretion have not previously been investigated. The main objective was to investigate sweat secretion rate and the GH-IGF-I axis in obese subjects before and after weight loss. Sixteen severely obese women (BMI, 40.6 ± 1.1 kg/m(2)) were investigated before and after a diet-induced weight loss. Sixteen age-matched nonobese women served as controls. The obese subjects presented the characteristic decreased GH release, hyperinsulinaemia, increased FFA levels, and impaired insulin sensitivity, which all were normalised after diet-induced weight loss of 30 ± 5 kg. Sweat secretion rates were similar comparing obese and nonobese subjects (78 ± 10 versus 82 ± 9 mg/30 minutes) and sweat secretion did not change after a diet-induced weight loss in obese subjects. We conclude that although obese subjects have markedly reduced GH release and impaired IGF-I levels, sweat secretion rate is found to be normal.

AB - Adults with GH deficiency are known to exhibit reduced sweating. Whether sweating capacity is impacted in obese subjects with impaired GH secretion have not previously been investigated. The main objective was to investigate sweat secretion rate and the GH-IGF-I axis in obese subjects before and after weight loss. Sixteen severely obese women (BMI, 40.6 ± 1.1 kg/m(2)) were investigated before and after a diet-induced weight loss. Sixteen age-matched nonobese women served as controls. The obese subjects presented the characteristic decreased GH release, hyperinsulinaemia, increased FFA levels, and impaired insulin sensitivity, which all were normalised after diet-induced weight loss of 30 ± 5 kg. Sweat secretion rates were similar comparing obese and nonobese subjects (78 ± 10 versus 82 ± 9 mg/30 minutes) and sweat secretion did not change after a diet-induced weight loss in obese subjects. We conclude that although obese subjects have markedly reduced GH release and impaired IGF-I levels, sweat secretion rate is found to be normal.

U2 - http://dx.doi.org/ 10.1155/2011/493840

DO - http://dx.doi.org/ 10.1155/2011/493840

M3 - Journal article

VL - 2011

SP - 493840

JO - International Journal of Endocrinology

JF - International Journal of Endocrinology

SN - 1687-8337

ER -

ID: 40167253