Neutrophil granules: a library of innate immunity proteins.

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Standard

Neutrophil granules: a library of innate immunity proteins. / Borregaard, Niels; Sørensen, Ole E; Theilgaard-Mönch, Kim.

I: Trends in Immunology, Bind 28, Nr. 8, 2007, s. 340-5.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Borregaard, N, Sørensen, OE & Theilgaard-Mönch, K 2007, 'Neutrophil granules: a library of innate immunity proteins.', Trends in Immunology, bind 28, nr. 8, s. 340-5. https://doi.org/10.1016/j.it.2007.06.002

APA

Borregaard, N., Sørensen, O. E., & Theilgaard-Mönch, K. (2007). Neutrophil granules: a library of innate immunity proteins. Trends in Immunology, 28(8), 340-5. https://doi.org/10.1016/j.it.2007.06.002

Vancouver

Borregaard N, Sørensen OE, Theilgaard-Mönch K. Neutrophil granules: a library of innate immunity proteins. Trends in Immunology. 2007;28(8):340-5. https://doi.org/10.1016/j.it.2007.06.002

Author

Borregaard, Niels ; Sørensen, Ole E ; Theilgaard-Mönch, Kim. / Neutrophil granules: a library of innate immunity proteins. I: Trends in Immunology. 2007 ; Bind 28, Nr. 8. s. 340-5.

Bibtex

@article{2de0b2f058ad11dd8d9f000ea68e967b,
title = "Neutrophil granules: a library of innate immunity proteins.",
abstract = "Gene expression profiling has revealed that circulating neutrophils rest between two major bursts of transcriptional and protein synthetic activities. The first occurs in the bone marrow. This equips the neutrophil with stocks of innate defense armory that are packaged into different granule subsets. The second burst occurs when the neutrophil exits circulation and migrates into tissues to find, capture and phagocytose microorganisms. This burst results in the synthesis and secretion of cytokines and chemokines that support resolution of inflammation and healing of damaged tissue. Gene expression profiling has revealed that neutrophils express a variety of innate immunity proteins, known previously only to be expressed in other cells. Likewise, it has become clear that some proteins previously thought to be specific to the neutrophil are expressed in epithelial cells during inflammation.",
author = "Niels Borregaard and S{\o}rensen, {Ole E} and Kim Theilgaard-M{\"o}nch",
note = "Keywords: Acute-Phase Proteins; Antimicrobial Cationic Peptides; Cytoplasmic Granules; Gene Expression Profiling; Humans; Immunity, Natural; Lipocalins; Neutrophils; Proto-Oncogene Proteins; Vesicle-Associated Membrane Protein 2",
year = "2007",
doi = "10.1016/j.it.2007.06.002",
language = "English",
volume = "28",
pages = "340--5",
journal = "Trends in Immunology",
issn = "1471-4906",
publisher = "Elsevier Ltd. * Trends Journals",
number = "8",

}

RIS

TY - JOUR

T1 - Neutrophil granules: a library of innate immunity proteins.

AU - Borregaard, Niels

AU - Sørensen, Ole E

AU - Theilgaard-Mönch, Kim

N1 - Keywords: Acute-Phase Proteins; Antimicrobial Cationic Peptides; Cytoplasmic Granules; Gene Expression Profiling; Humans; Immunity, Natural; Lipocalins; Neutrophils; Proto-Oncogene Proteins; Vesicle-Associated Membrane Protein 2

PY - 2007

Y1 - 2007

N2 - Gene expression profiling has revealed that circulating neutrophils rest between two major bursts of transcriptional and protein synthetic activities. The first occurs in the bone marrow. This equips the neutrophil with stocks of innate defense armory that are packaged into different granule subsets. The second burst occurs when the neutrophil exits circulation and migrates into tissues to find, capture and phagocytose microorganisms. This burst results in the synthesis and secretion of cytokines and chemokines that support resolution of inflammation and healing of damaged tissue. Gene expression profiling has revealed that neutrophils express a variety of innate immunity proteins, known previously only to be expressed in other cells. Likewise, it has become clear that some proteins previously thought to be specific to the neutrophil are expressed in epithelial cells during inflammation.

AB - Gene expression profiling has revealed that circulating neutrophils rest between two major bursts of transcriptional and protein synthetic activities. The first occurs in the bone marrow. This equips the neutrophil with stocks of innate defense armory that are packaged into different granule subsets. The second burst occurs when the neutrophil exits circulation and migrates into tissues to find, capture and phagocytose microorganisms. This burst results in the synthesis and secretion of cytokines and chemokines that support resolution of inflammation and healing of damaged tissue. Gene expression profiling has revealed that neutrophils express a variety of innate immunity proteins, known previously only to be expressed in other cells. Likewise, it has become clear that some proteins previously thought to be specific to the neutrophil are expressed in epithelial cells during inflammation.

U2 - 10.1016/j.it.2007.06.002

DO - 10.1016/j.it.2007.06.002

M3 - Journal article

C2 - 17627888

VL - 28

SP - 340

EP - 345

JO - Trends in Immunology

JF - Trends in Immunology

SN - 1471-4906

IS - 8

ER -

ID: 5142784