N-acyliminium intermediates in solid-phase synthesis.
Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt
N-Acyliminium ions are powerful intermediates in synthetic organic chemistry. Examples of their use are numerous in solution-phase synthesis, but there are unmerited few reports on these highly reactive electrophiles in solid-phase synthesis. The present review covers the literature to date and illustrates the methods used to generate N-acyliminium intermediates on solid support and their further elaboration to a range of pharmacologically interesting peptidomimetics, heterocycles, and other small molecules.
Originalsprog | Engelsk |
---|---|
Tidsskrift | Biopolymers |
Vol/bind | 94 |
Udgave nummer | 2 |
Sider (fra-til) | 242-256 |
Antal sider | 15 |
ISSN | 0006-3525 |
DOI | |
Status | Udgivet - 2010 |
Eksternt udgivet | Ja |
ID: 321824844