Microvascular reconstruction in head and neck cancer - basis for the development of an enhanced recovery protocol
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Microvascular reconstruction in head and neck cancer - basis for the development of an enhanced recovery protocol. / Højvig, Jens H.; Pedersen, Nicolas J.; Charabi, Birgitte W.; Wessel, Irene; Jensen, Lisa T.; Nyberg, Jan; Mayman-Holler, Nana; Kehlet, Henrik; Bonde, Christian T.
I: JPRAS Open, Bind 26, 2020, s. 91-100.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Microvascular reconstruction in head and neck cancer - basis for the development of an enhanced recovery protocol
AU - Højvig, Jens H.
AU - Pedersen, Nicolas J.
AU - Charabi, Birgitte W.
AU - Wessel, Irene
AU - Jensen, Lisa T.
AU - Nyberg, Jan
AU - Mayman-Holler, Nana
AU - Kehlet, Henrik
AU - Bonde, Christian T.
PY - 2020
Y1 - 2020
N2 - Introduction: Microvascular reconstructions after head and neck cancer are among the most complicated procedures in plastic surgery. Postoperative complications are common, which often leads to prolonged hospital stay. Enhanced recovery after surgery (ERAS) is a peri- and postoperative care concept with the aim of achieving pain- and risk-free surgery. It has been previously established as superior to conventional care for a wide variety of procedures, including microsurgical procedures such as reconstructions of the breast. Several ERAS protocols for microvascular head and neck cancer reconstructions have been proposed, although most of these are based on extrapolated evidence from different surgical specialties. Results from the implementation of ERAS for these procedures are inconsistent. Methods: The current study investigates our clinical experience of head and neck cancer reconstruction for the period of 2014-2016 with the aim of establishing a list of functional discharge criteria. By combining these with the current published knowledge on the subject, we developed an ERAS protocol. Results: We performed 89 microvascular procedures in the study period, of which 58 were in the oral cavity/sinuses and 31 were laryngopharyngeal. Most cases were squamous cell carcinoma (89%). The average LOS was 20.3 days in both groups. Postoperative complications included infection (37%), 30-days re-operations (19%), and re-admissions (17%). Furthermore, we identified the following discharge criteria: adequate pain relief, ambulation, sufficient nutritional intake, normal infection-related blood parameter results and absence of fever, bowel function, and closure of tracheostomy. Conclusion: Based on our retrospective analysis and identified discharge criteria, we present an approach to develop an ERAS protocol for microvascular reconstruction after head and neck cancer.
AB - Introduction: Microvascular reconstructions after head and neck cancer are among the most complicated procedures in plastic surgery. Postoperative complications are common, which often leads to prolonged hospital stay. Enhanced recovery after surgery (ERAS) is a peri- and postoperative care concept with the aim of achieving pain- and risk-free surgery. It has been previously established as superior to conventional care for a wide variety of procedures, including microsurgical procedures such as reconstructions of the breast. Several ERAS protocols for microvascular head and neck cancer reconstructions have been proposed, although most of these are based on extrapolated evidence from different surgical specialties. Results from the implementation of ERAS for these procedures are inconsistent. Methods: The current study investigates our clinical experience of head and neck cancer reconstruction for the period of 2014-2016 with the aim of establishing a list of functional discharge criteria. By combining these with the current published knowledge on the subject, we developed an ERAS protocol. Results: We performed 89 microvascular procedures in the study period, of which 58 were in the oral cavity/sinuses and 31 were laryngopharyngeal. Most cases were squamous cell carcinoma (89%). The average LOS was 20.3 days in both groups. Postoperative complications included infection (37%), 30-days re-operations (19%), and re-admissions (17%). Furthermore, we identified the following discharge criteria: adequate pain relief, ambulation, sufficient nutritional intake, normal infection-related blood parameter results and absence of fever, bowel function, and closure of tracheostomy. Conclusion: Based on our retrospective analysis and identified discharge criteria, we present an approach to develop an ERAS protocol for microvascular reconstruction after head and neck cancer.
KW - enhanced recovery after surgery
KW - ERAS
KW - free flap surgery
KW - Head and neck
KW - head and neck cancer
KW - microvascular reconstruction
U2 - 10.1016/j.jpra.2020.09.008
DO - 10.1016/j.jpra.2020.09.008
M3 - Journal article
C2 - 33225037
AN - SCOPUS:85097418680
VL - 26
SP - 91
EP - 100
JO - J P R A S Open
JF - J P R A S Open
SN - 2352-5878
ER -
ID: 260601164