Maternal HY-restricting HLA class II alleles are associated with poor long-term outcome in recurrent pregnancy loss after a boy

Publikation: Bidrag til tidsskrift › Letter › Forskning › fagfællebedømt

Standard

Maternal HY-restricting HLA class II alleles are associated with poor long-term outcome in recurrent pregnancy loss after a boy. / Kolte, Astrid Marie; Steffensen, Rudi; Christiansen, Ole Bjarne; Nielsen, Henriette Svarre.

I: American Journal of Reproductive Immunology, Bind 76, Nr. 5, 11.2016, s. 400-405.

Publikation: Bidrag til tidsskrift › Letter › Forskning › fagfællebedømt

Harvard

Kolte, AM, Steffensen, R, Christiansen, OB & Nielsen, HS 2016, 'Maternal HY-restricting HLA class II alleles are associated with poor long-term outcome in recurrent pregnancy loss after a boy', American Journal of Reproductive Immunology, bind 76, nr. 5, s. 400-405. https://doi.org/10.1111/aji.12561

APA

Kolte, A. M., Steffensen, R., Christiansen, O. B., & Nielsen, H. S. (2016). Maternal HY-restricting HLA class II alleles are associated with poor long-term outcome in recurrent pregnancy loss after a boy. American Journal of Reproductive Immunology, 76(5), 400-405. https://doi.org/10.1111/aji.12561

Vancouver

Kolte AM, Steffensen R, Christiansen OB, Nielsen HS. Maternal HY-restricting HLA class II alleles are associated with poor long-term outcome in recurrent pregnancy loss after a boy. American Journal of Reproductive Immunology. 2016 nov.;76(5):400-405. https://doi.org/10.1111/aji.12561

Author

Kolte, Astrid Marie ; Steffensen, Rudi ; Christiansen, Ole Bjarne ; Nielsen, Henriette Svarre. / Maternal HY-restricting HLA class II alleles are associated with poor long-term outcome in recurrent pregnancy loss after a boy. I: American Journal of Reproductive Immunology. 2016 ; Bind 76, Nr. 5. s. 400-405.

Bibtex

@article{587c202a6dfa48ab98c569d3ac9f329c,
title = "Maternal HY-restricting HLA class II alleles are associated with poor long-term outcome in recurrent pregnancy loss after a boy",
abstract = "PROBLEM: Women with secondary recurrent pregnancy loss (RPL) after a boy have a reduced chance of live birth in the first pregnancy after referral if they carry HY-restricting HLA class II alleles, but long-term chance of live birth is unknown.METHODS OF STUDY: Live birth was compared for 540 women with unexplained secondary RPL according to firstborn's sex and maternal carriage of HLA-DRB3*03:01, HLA-DQB1*05:01/02, HLA-DRB1*15, and HLA-DRB1*07. The groups were compared by Cox proportional hazard ratios.RESULTS: For women with at firstborn boy, maternal carriage of HY-restricting HLA class II alleles decreased chance of live birth: 0 vs 1: hazard ratio 0.75 (95% CI 0.55-1.02); 0 vs 2: HR 0.62 (0.40-0.94). Carriage of HY-restricting HLA class II alleles decreased chance of live birth only if the firstborn was a boy: boy vs girl: HR 0.72 (95% CI 0.55-0.98).CONCLUSION: Maternal carriage of HY-restricting HLA class II alleles decreases long-term chance of live birth in women with RPL after a boy.",
keywords = "Journal Article",
author = "Kolte, {Astrid Marie} and Rudi Steffensen and Christiansen, {Ole Bjarne} and Nielsen, {Henriette Svarre}",
note = "{\textcopyright} 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.",
year = "2016",
month = nov,
doi = "10.1111/aji.12561",
language = "English",
volume = "76",
pages = "400--405",
journal = "Early pregnancy : biology and medicine : the official journal of the Society for the Investigation of Early Pregnancy",
issn = "1046-7408",
publisher = "Wiley-Blackwell",
number = "5",

}

RIS

TY - JOUR

T1 - Maternal HY-restricting HLA class II alleles are associated with poor long-term outcome in recurrent pregnancy loss after a boy

AU - Kolte, Astrid Marie

AU - Steffensen, Rudi

AU - Christiansen, Ole Bjarne

AU - Nielsen, Henriette Svarre

N1 - © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

PY - 2016/11

Y1 - 2016/11

N2 - PROBLEM: Women with secondary recurrent pregnancy loss (RPL) after a boy have a reduced chance of live birth in the first pregnancy after referral if they carry HY-restricting HLA class II alleles, but long-term chance of live birth is unknown.METHODS OF STUDY: Live birth was compared for 540 women with unexplained secondary RPL according to firstborn's sex and maternal carriage of HLA-DRB3*03:01, HLA-DQB1*05:01/02, HLA-DRB1*15, and HLA-DRB1*07. The groups were compared by Cox proportional hazard ratios.RESULTS: For women with at firstborn boy, maternal carriage of HY-restricting HLA class II alleles decreased chance of live birth: 0 vs 1: hazard ratio 0.75 (95% CI 0.55-1.02); 0 vs 2: HR 0.62 (0.40-0.94). Carriage of HY-restricting HLA class II alleles decreased chance of live birth only if the firstborn was a boy: boy vs girl: HR 0.72 (95% CI 0.55-0.98).CONCLUSION: Maternal carriage of HY-restricting HLA class II alleles decreases long-term chance of live birth in women with RPL after a boy.

AB - PROBLEM: Women with secondary recurrent pregnancy loss (RPL) after a boy have a reduced chance of live birth in the first pregnancy after referral if they carry HY-restricting HLA class II alleles, but long-term chance of live birth is unknown.METHODS OF STUDY: Live birth was compared for 540 women with unexplained secondary RPL according to firstborn's sex and maternal carriage of HLA-DRB3*03:01, HLA-DQB1*05:01/02, HLA-DRB1*15, and HLA-DRB1*07. The groups were compared by Cox proportional hazard ratios.RESULTS: For women with at firstborn boy, maternal carriage of HY-restricting HLA class II alleles decreased chance of live birth: 0 vs 1: hazard ratio 0.75 (95% CI 0.55-1.02); 0 vs 2: HR 0.62 (0.40-0.94). Carriage of HY-restricting HLA class II alleles decreased chance of live birth only if the firstborn was a boy: boy vs girl: HR 0.72 (95% CI 0.55-0.98).CONCLUSION: Maternal carriage of HY-restricting HLA class II alleles decreases long-term chance of live birth in women with RPL after a boy.

KW - Journal Article

U2 - 10.1111/aji.12561

DO - 10.1111/aji.12561

M3 - Letter

C2 - 27600856

VL - 76

SP - 400

EP - 405

JO - Early pregnancy : biology and medicine : the official journal of the Society for the Investigation of Early Pregnancy

JF - Early pregnancy : biology and medicine : the official journal of the Society for the Investigation of Early Pregnancy

SN - 1046-7408

IS - 5

ER -

ID: 179284938