Management of Patients with Oral Candidiasis
Publikation: Bidrag til bog/antologi/rapport › Bidrag til bog/antologi › Forskning › fagfællebedømt
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Management of Patients with Oral Candidiasis. / Kragelund, Camilla; Reibel, Jesper; Pedersen, Anne Marie Lynge.
Oral Infections and General Health : From Molecule to Chairside. red. / Anne Marie Lynge Pedersen. 1. udg. Heidelberg : Springer, 2016. s. 137-144.Publikation: Bidrag til bog/antologi/rapport › Bidrag til bog/antologi › Forskning › fagfællebedømt
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TY - CHAP
T1 - Management of Patients with Oral Candidiasis
AU - Kragelund, Camilla
AU - Reibel, Jesper
AU - Pedersen, Anne Marie Lynge
PY - 2016/1
Y1 - 2016/1
N2 - Oral candidal infections are medically treated with antifungal agents. In the fungal cell membrane, steroid ergosterol is the target of the antifungals on the market, but similarity with the human cell membrane may cause host toxicity and unintended reactions. Management of oral candidiasis depends on several factors, some are host-sensitive parameters, systemic diseases and drug exposure, and others are infection-sensitive parameters, duration of the infection and the virulence of the infecting Candida species. Treatment failure might be associated with acquired or native azole resistance in particular in patients with recurrent oral candidiasis. This risk can be reduced if different types of antifungal drugs are used over time or are combined. This chapter focuses on antifungal treatment of the medically compromised patient with oral candidiasis by highlighting the advantages and disadvantages of different antifungals.
AB - Oral candidal infections are medically treated with antifungal agents. In the fungal cell membrane, steroid ergosterol is the target of the antifungals on the market, but similarity with the human cell membrane may cause host toxicity and unintended reactions. Management of oral candidiasis depends on several factors, some are host-sensitive parameters, systemic diseases and drug exposure, and others are infection-sensitive parameters, duration of the infection and the virulence of the infecting Candida species. Treatment failure might be associated with acquired or native azole resistance in particular in patients with recurrent oral candidiasis. This risk can be reduced if different types of antifungal drugs are used over time or are combined. This chapter focuses on antifungal treatment of the medically compromised patient with oral candidiasis by highlighting the advantages and disadvantages of different antifungals.
U2 - 10.1007/978-3-319-25091-5_13
DO - 10.1007/978-3-319-25091-5_13
M3 - Book chapter
SN - 978-3-319-25089-2
SP - 137
EP - 144
BT - Oral Infections and General Health
A2 - Pedersen, Anne Marie Lynge
PB - Springer
CY - Heidelberg
ER -
ID: 162686602