TY - JOUR

T1 - Major dietary patterns in pregnancy and fetal growth

AU - Knudsen, V. K.

AU - Orozova-Bekkevold, I. M.

AU - Mikkelsen, T. B.

AU - Wolff, S.

AU - Olsen, S. F.

N1 - Funding Information: We thank Mr Kenn S Nielsen for the technical and data management support and the managerial team of the Danish National Birth Cohort, which consisted of: Jørn Olsen (Chair), Mads Melbye, Anne Marie Nybo Andersen, Sjurdur F Olsen, Thorkild IA Sørensen and Peter Aabye. Financial support for the Danish National Birth Cohort was obtained from the March of Dimes Birth Defects Foundation, the Danish National Research Foundation, the European Union (QLK1-2000-00083), the Pharmacy Foundation, the Egmont Foundation, the Augustinus Foundation and the Health Foundation.

PY - 2008

Y1 - 2008

N2 - Objectives: To investigate possible associations between maternal diet during pregnancy and fetal growth. Method: Factor analysis was used to explore dietary patterns among pregnant women. The association between maternal dietary patterns and fetal growth (in terms of small for gestational age, SGA) was investigated by logistic regression. Prospective cohort study, including information on 44612 women in Denmark. Results: Two major dietary patterns were defined: the first pattern was characterized by red and processed meat, high-fat dairy, and the second pattern was characterized by intake of vegetables, fruits, poultry and fish. Women were classified into three classes according to their diet: the first class had high intake of foods of the first dietary pattern, and was classified as 'the Western diet', the second class preferred foods of the second pattern and was classified as the 'Health Conscious'; and the third one had eaten foods of both patterns, and was classified as the 'Intermediate'. The odds ratio of having a small for gestational-age infant (with a birth weight below the 2.5th percentile for gestational age and gender) was 0.74 (95% CI 0.64-0.86) for women in the Health Conscious class compared with women in the Western Diet class. The analyses were adjusted for parity, maternal smoking, age, height, pre-pregnancy weight and father's height. Conclusions: Our results indicated that a diet in pregnancy, based on red and processed meat and high-fat diary, was associated with increased risk for SGA. Further studies are warranted to identify specific macro-, or micronutrients that may be underlying these associations.

AB - Objectives: To investigate possible associations between maternal diet during pregnancy and fetal growth. Method: Factor analysis was used to explore dietary patterns among pregnant women. The association between maternal dietary patterns and fetal growth (in terms of small for gestational age, SGA) was investigated by logistic regression. Prospective cohort study, including information on 44612 women in Denmark. Results: Two major dietary patterns were defined: the first pattern was characterized by red and processed meat, high-fat dairy, and the second pattern was characterized by intake of vegetables, fruits, poultry and fish. Women were classified into three classes according to their diet: the first class had high intake of foods of the first dietary pattern, and was classified as 'the Western diet', the second class preferred foods of the second pattern and was classified as the 'Health Conscious'; and the third one had eaten foods of both patterns, and was classified as the 'Intermediate'. The odds ratio of having a small for gestational-age infant (with a birth weight below the 2.5th percentile for gestational age and gender) was 0.74 (95% CI 0.64-0.86) for women in the Health Conscious class compared with women in the Western Diet class. The analyses were adjusted for parity, maternal smoking, age, height, pre-pregnancy weight and father's height. Conclusions: Our results indicated that a diet in pregnancy, based on red and processed meat and high-fat diary, was associated with increased risk for SGA. Further studies are warranted to identify specific macro-, or micronutrients that may be underlying these associations.

U2 - 10.1038/sj.ejcn.1602745

DO - 10.1038/sj.ejcn.1602745

M3 - Journal article

C2 - 17392696

AN - SCOPUS:47949083569

VL - 62

SP - 463

EP - 470

JO - European Journal of Clinical Nutrition

JF - European Journal of Clinical Nutrition

SN - 0954-3007

IS - 4

ER -