Lung function in Greenlandic and Danish children and adolescents
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Lung function in Greenlandic and Danish children and adolescents. / Krause, Tyra Grove; Pedersen, Bo V.; Thomsen, Simon Francis; Koch, Anders; Wohlfahrt, Jan; Backer, Vibeke; Melbye, Mads.
I: Respiratory Medicine, Bind 99, Nr. 3, 03.2005, s. 363-371.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Lung function in Greenlandic and Danish children and adolescents
AU - Krause, Tyra Grove
AU - Pedersen, Bo V.
AU - Thomsen, Simon Francis
AU - Koch, Anders
AU - Wohlfahrt, Jan
AU - Backer, Vibeke
AU - Melbye, Mads
PY - 2005/3
Y1 - 2005/3
N2 - Respiratory morbidity in Inuit children is high. However, little is know regarding lung function measures in this population. The forced expirat ory volumes in one second (FEV1) and forced vital capacity (FVC) in 888 Greenlandic Inuits (N = 888) and Danes (N = 477) aged 6-18 years were compared. Furthermore, associations between level of lung function and atopy and lifestyle factors were estimated in Greenlanders. The effect of height on FEV1 and FVC was significantly different in Greenlanders and Danes, this difference in lung function increased with increasing height, and could not be explained by differences in age weight and BMI. Thus, Greenlanders taller than 130 cm had up to 300-400 ml higher FEV1 and FVC compared with Danes of the same height. Among Greenlanders, those living in settlements had the highest levels of both FEV1 and FVC. Greenlanders had elevated levels of FEV1 and FVC compared with Danes. The Inuit having a shorter limb length in relation to trunk height may account for these differences. However, our finding that Greenlanders living in settlements had the highest lung function level also suggests a possible role of factors in the traditional Greenlandic lifestyle.
AB - Respiratory morbidity in Inuit children is high. However, little is know regarding lung function measures in this population. The forced expirat ory volumes in one second (FEV1) and forced vital capacity (FVC) in 888 Greenlandic Inuits (N = 888) and Danes (N = 477) aged 6-18 years were compared. Furthermore, associations between level of lung function and atopy and lifestyle factors were estimated in Greenlanders. The effect of height on FEV1 and FVC was significantly different in Greenlanders and Danes, this difference in lung function increased with increasing height, and could not be explained by differences in age weight and BMI. Thus, Greenlanders taller than 130 cm had up to 300-400 ml higher FEV1 and FVC compared with Danes of the same height. Among Greenlanders, those living in settlements had the highest levels of both FEV1 and FVC. Greenlanders had elevated levels of FEV1 and FVC compared with Danes. The Inuit having a shorter limb length in relation to trunk height may account for these differences. However, our finding that Greenlanders living in settlements had the highest lung function level also suggests a possible role of factors in the traditional Greenlandic lifestyle.
KW - Children
KW - Denmark
KW - Greenland
KW - Inuit
KW - Lung function
KW - Spirometry
UR - http://www.scopus.com/inward/record.url?scp=13944255926&partnerID=8YFLogxK
U2 - 10.1016/j.rmed.2004.07.016
DO - 10.1016/j.rmed.2004.07.016
M3 - Journal article
C2 - 15733513
AN - SCOPUS:13944255926
VL - 99
SP - 363
EP - 371
JO - Respiratory Medicine
JF - Respiratory Medicine
SN - 0954-6111
IS - 3
ER -
ID: 259458918