Laribacter hongkongensis: clinical presentation, epidemiology and treatment. A review of the literature and report of the first case in Denmark
Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt
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Laribacter hongkongensis : clinical presentation, epidemiology and treatment. A review of the literature and report of the first case in Denmark. / Engsbro, Anne Line; Nielsen, Karen Leth; Hornum, Mads; Andersen, Leif Percival.
I: Infectious Diseases, Bind 50, Nr. 6, 2018, s. 417-422.Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt
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TY - JOUR
T1 - Laribacter hongkongensis
T2 - clinical presentation, epidemiology and treatment. A review of the literature and report of the first case in Denmark
AU - Engsbro, Anne Line
AU - Nielsen, Karen Leth
AU - Hornum, Mads
AU - Andersen, Leif Percival
PY - 2018
Y1 - 2018
N2 - Background: Laribacter hongkongensis is an emerging pathogen related to gastroenteritis that can cause invasive and even fatal disease. The aim of this review is to describe the clinical presentation, epidemiology, treatment options and implications for the clinical microbiology laboratory. Methods: We searched Pubmed using the term Laribacter hongkongensis with limitations human and language English, and identified 35 publications with eight reports on human cases. Results: We describe our first case of prolonged, travel-related gastroenteritis where Laribacter hongkongensis was isolated as the sole pathogen. Our review suggests that L. hongkongensis causes non-bloody acute diarrhoea with potential for invasive disease, since three cases of bacteraemia and one case of dialysis related peritonitis have been described previously. L. hongkongensis has primarily been described in Asia, but reports from Europe, North America and Australia suggests a worldwide distribution. Broad culturing with subsequent identification by the MALDI-TOF is the current strategy for detection of L. hongkongensis. Phenotypic susceptibility testing is necessary to guide the treatment choice. Few resistance genes have been described in L. hongkongensis. Conclusion: L. hongkongensis should be considered a potential cause of acute and prolonged diarrhoea. Clinicians must be aware of the test methods in the local clinical microbiology laboratory, since L. hongkongensis is difficult to detect and easily overlooked.
AB - Background: Laribacter hongkongensis is an emerging pathogen related to gastroenteritis that can cause invasive and even fatal disease. The aim of this review is to describe the clinical presentation, epidemiology, treatment options and implications for the clinical microbiology laboratory. Methods: We searched Pubmed using the term Laribacter hongkongensis with limitations human and language English, and identified 35 publications with eight reports on human cases. Results: We describe our first case of prolonged, travel-related gastroenteritis where Laribacter hongkongensis was isolated as the sole pathogen. Our review suggests that L. hongkongensis causes non-bloody acute diarrhoea with potential for invasive disease, since three cases of bacteraemia and one case of dialysis related peritonitis have been described previously. L. hongkongensis has primarily been described in Asia, but reports from Europe, North America and Australia suggests a worldwide distribution. Broad culturing with subsequent identification by the MALDI-TOF is the current strategy for detection of L. hongkongensis. Phenotypic susceptibility testing is necessary to guide the treatment choice. Few resistance genes have been described in L. hongkongensis. Conclusion: L. hongkongensis should be considered a potential cause of acute and prolonged diarrhoea. Clinicians must be aware of the test methods in the local clinical microbiology laboratory, since L. hongkongensis is difficult to detect and easily overlooked.
KW - Diarrhea
KW - Kidney transplant
KW - Laribacter hongkongensis
KW - Susceptibility
KW - Weight loss
KW - Whole genome sequencing
U2 - 10.1080/23744235.2017.1419373
DO - 10.1080/23744235.2017.1419373
M3 - Review
C2 - 29272955
AN - SCOPUS:85038825590
VL - 50
SP - 417
EP - 422
JO - Infectious Diseases
JF - Infectious Diseases
SN - 2374-4235
IS - 6
ER -
ID: 188271065