Kvalme og opkastning induceret af medicinsk kræftbehandling
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Kvalme og opkastning induceret af medicinsk kræftbehandling. / Petersen, Peter Clausager; Ruhlmann, Christina; Herrstedt, Jørn.
I: Ugeskrift for Laeger, Bind 181, V02190115, 2019.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Kvalme og opkastning induceret af medicinsk kræftbehandling
AU - Petersen, Peter Clausager
AU - Ruhlmann, Christina
AU - Herrstedt, Jørn
PY - 2019
Y1 - 2019
N2 - Nausea and vomiting are a persistent burden on cancer patients undergoing antineoplastic therapy, and adherence to guideline-specific prophylactic therapy is essential to minimise the risk. Nausea is more challenging to prevent than vomiting. This review summarises the choices of relevant drugs. Olanzapine is effective against nausea, but sedation can be a problem. There seems to be no major differences in effect or tolerability between different serotonin receptor antagonists and different neurokinin receptor antagonists. Consequently, the choice of drug should be based on price, risk of interactions and simple administration.
AB - Nausea and vomiting are a persistent burden on cancer patients undergoing antineoplastic therapy, and adherence to guideline-specific prophylactic therapy is essential to minimise the risk. Nausea is more challenging to prevent than vomiting. This review summarises the choices of relevant drugs. Olanzapine is effective against nausea, but sedation can be a problem. There seems to be no major differences in effect or tolerability between different serotonin receptor antagonists and different neurokinin receptor antagonists. Consequently, the choice of drug should be based on price, risk of interactions and simple administration.
KW - Antiemetics/therapeutic use
KW - Antineoplastic Agents/adverse effects
KW - Humans
KW - Nausea/chemically induced
KW - Neoplasms/drug therapy
KW - Vomiting/chemically induced
M3 - Tidsskriftartikel
C2 - 31267940
VL - 181
JO - Ugeskrift for Laeger
JF - Ugeskrift for Laeger
SN - 0041-5782
M1 - V02190115
ER -
ID: 240952287