Kinetics and dose calculations of ampicillin and gentamicin given as continuous intravenous infusion during parenteral nutrition in 88 newborn infants.

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Standard

Kinetics and dose calculations of ampicillin and gentamicin given as continuous intravenous infusion during parenteral nutrition in 88 newborn infants. / Colding, H; Møller, S; Bentzon, M W.

I: Developmental Pharmacology and Therapeutics, Bind 6, Nr. 6, 1983, s. 365-73.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Colding, H, Møller, S & Bentzon, MW 1983, 'Kinetics and dose calculations of ampicillin and gentamicin given as continuous intravenous infusion during parenteral nutrition in 88 newborn infants.', Developmental Pharmacology and Therapeutics, bind 6, nr. 6, s. 365-73.

APA

Colding, H., Møller, S., & Bentzon, M. W. (1983). Kinetics and dose calculations of ampicillin and gentamicin given as continuous intravenous infusion during parenteral nutrition in 88 newborn infants. Developmental Pharmacology and Therapeutics, 6(6), 365-73.

Vancouver

Colding H, Møller S, Bentzon MW. Kinetics and dose calculations of ampicillin and gentamicin given as continuous intravenous infusion during parenteral nutrition in 88 newborn infants. Developmental Pharmacology and Therapeutics. 1983;6(6):365-73.

Author

Colding, H ; Møller, S ; Bentzon, M W. / Kinetics and dose calculations of ampicillin and gentamicin given as continuous intravenous infusion during parenteral nutrition in 88 newborn infants. I: Developmental Pharmacology and Therapeutics. 1983 ; Bind 6, Nr. 6. s. 365-73.

Bibtex

@article{fe3a1cf0b55211ddb04f000ea68e967b,

title = "Kinetics and dose calculations of ampicillin and gentamicin given as continuous intravenous infusion during parenteral nutrition in 88 newborn infants.",

abstract = "Ampicillin and gentamicin were administered continuously intravenously to 88 newborn infants using individually calculated dosages. For infants with a mean value of plasma clearance of the antibiotics, it was calculated that the serum ampicillin and gentamicin concentrations would be between 35-55 and 3-5 micrograms/ml, respectively, using the dosages for intermittent treatment. These dosages are therefore recommended as fixed dosages for continuous intravenous infusion initiated by a bolus dosage. Serum gentamicin concentration should be assayed about three half-lives after start of infusion and the dosage adjusted for values outside 3-5 micrograms/ml.",

author = "H Colding and S M{\o}ller and Bentzon, {M W}",

note = "Keywords: Ampicillin; Female; Gentamicins; Half-Life; Humans; Infant, Newborn; Infusions, Parenteral; Kinetics; Male; Parenteral Nutrition",

year = "1983",

language = "English",

volume = "6",

pages = "365--73",

journal = "Developmental Pharmacology and Therapeutics",

issn = "0379-8305",

publisher = "S. Karger AG",

number = "6",

}

RIS

TY - JOUR

T1 - Kinetics and dose calculations of ampicillin and gentamicin given as continuous intravenous infusion during parenteral nutrition in 88 newborn infants.

AU - Colding, H

AU - Møller, S

AU - Bentzon, M W

N1 - Keywords: Ampicillin; Female; Gentamicins; Half-Life; Humans; Infant, Newborn; Infusions, Parenteral; Kinetics; Male; Parenteral Nutrition

PY - 1983

Y1 - 1983

N2 - Ampicillin and gentamicin were administered continuously intravenously to 88 newborn infants using individually calculated dosages. For infants with a mean value of plasma clearance of the antibiotics, it was calculated that the serum ampicillin and gentamicin concentrations would be between 35-55 and 3-5 micrograms/ml, respectively, using the dosages for intermittent treatment. These dosages are therefore recommended as fixed dosages for continuous intravenous infusion initiated by a bolus dosage. Serum gentamicin concentration should be assayed about three half-lives after start of infusion and the dosage adjusted for values outside 3-5 micrograms/ml.

AB - Ampicillin and gentamicin were administered continuously intravenously to 88 newborn infants using individually calculated dosages. For infants with a mean value of plasma clearance of the antibiotics, it was calculated that the serum ampicillin and gentamicin concentrations would be between 35-55 and 3-5 micrograms/ml, respectively, using the dosages for intermittent treatment. These dosages are therefore recommended as fixed dosages for continuous intravenous infusion initiated by a bolus dosage. Serum gentamicin concentration should be assayed about three half-lives after start of infusion and the dosage adjusted for values outside 3-5 micrograms/ml.

M3 - Journal article

C2 - 6416802

VL - 6

SP - 365

EP - 373

JO - Developmental Pharmacology and Therapeutics

JF - Developmental Pharmacology and Therapeutics

SN - 0379-8305

IS - 6

ER -

ID: 8670182